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Advances in the effects of preeclampsia on brain structure and function
WU Muxi  SHEN Guiquan  GAO Bo 

Cite this article as: Wu MX, Shen GQ, Gao B. Advances in the effects of preeclampsia on brain structure and function. Chin J Magn Reson Imaging, 2019, 10(12): 924-927. DOI:10.12015/issn.1674-8034.2019.12.011.


[Abstract] Preeclampsia (PE) is a pregnancy-specific syndrome affecting multiple organs including the brain. Although the symptoms of PE will gradually subside after termination of pregnancy or delivery, the history of preeclampsia (HPE) will become a risk factor for hypertension and cardiovascular disease (CVD) in women's later life, so PE may be associated with cognitive impairment. Studies have shown that long-term pathological changes may occur in the brain of women with HPE, such as persistent white matter lesions (WML), and PE may be a risk marker for early cerebrovascular damage. The long-term effects of PE are mainly cognitive impairment, such as memory loss, inattention and slow response. In addition, some changes in brain structure and function in elderly women with HPE were found to be similar to those in some neurological diseases, such as Alzheimer's disease (AD). This article aims to explore the possible long-term effects of PE on brain structure and function. The author reviews the neuroimaging research progress of preeclampsia.
[Keywords] pre-eclampsia；white matter；gray matter；white matter lesions；cognitive dysfunction；magnetic resonance imaging

WU Muxi Department of Radiology, the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China

SHEN Guiquan * Department of Radiology, the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China

GAO Bo Department of Radiology, the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China

*Corresponding to: Shen GQ, E-mail:gzshenguiquan@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 81871333
Received  2019-05-25
DOI: 10.12015/issn.1674-8034.2019.12.011
Cite this article as: Wu MX, Shen GQ, Gao B. Advances in the effects of preeclampsia on brain structure and function. Chin J Magn Reson Imaging, 2019, 10(12): 924-927. DOI:10.12015/issn.1674-8034.2019.12.011.

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