Share：
Share this content in WeChat
X
[Chinese][PDF]90581
• Clinical Article •
The research value of quantitative study of parotid gland fat infiltration in early Sjogren's syndrome patients by using 3.0 T MR IDEAL-IQ sequence
WANG Haitian  ZHAO Xiankun  Wang Guohua  FANG Ming  ZHAO Hongfei 

Cite this article as: Wang HT, Zhao XK, Wang GH, et al. The research value of quantitative study of parotid gland fat infiltration in early Sjogren's syndrome patients by using 3.0 T MR IDEAL-IQ sequence. Chin J Magn Reson Imaging, 2020, 11(1): 25-28. DOI:10.12015/issn.1674-8034.2020.01.006.


[Abstract] Objective: To quantitatively measure the fat fraction (FF) of parotid gland in patients with early Sjogren's syndrome and healthy volunteers by using 3.0 T MR IDEAL-IQ sequence, and to evaluate the infiltration of parotid gland fat, so as to provide a new diagnostic basis for the clinic.Materials and Methods: From January 2019 to July 2019, 31 female patients with early Sjogren's syndrome and 30 healthy female volunteers admitted to Qingdao municipal hospital were enrolled in the routine parotid MRI sequence scanning and the IDEAL-IQ sequence axial scanning. The GE ADW 4.6 workstation processing software was used to quantitatively measure the FF value of the parotid gland, and statistical analysis was performed on the FF values of the bilateral parotid glands in the early Sjogren's syndrome patients and healthy volunteers.Results: There was no significant difference in age and BMI between the two groups (P>0.05). There were no differences on FF values in the left and right parotid gland in patients with early Sjogren's syndrome andhealthy volunteers (P>0.05). The mean FF value of parotid gland in patients with early Sjogren's syndrome was significantly higher than that in the normal group (48.84±11.26 vs 32.15±6.58, P<0.01). The mean FF 37.62 was taken as the optimal value for early Sjogren's syndrome diagnosis (AUC=0.92, sensitivity 0.88, specificity 0.81).Conclusions: The IDEAL-IQ sequence and FF value of parotid gland play a certain role in the diagnosis of early Sjogren's syndrome, which can provide valuable information for the diagnosis of early Sjogren's syndrome.
[Keywords] Sjogren's syndrome；parotid gland；fatty infiltration；magnetic resonance imaging

WANG Haitian Department of Radiology, Qingdao Municipal Hospital Affiliated to Qingdao University, Qingdao 266000, China; Shandong First Medical University & Shandong Academy of Medical Sciences, Taian 271000, China

ZHAO Xiankun Medical Devices Section, Qingdao Municipal Hospital Affiliated to Qingdao University, Qingdao 266000, China

Wang Guohua* Department of Radiology, Qingdao Municipal Hospital Affiliated to Qingdao University, Qingdao 266000, China

FANG Ming Department of Radiology, Qingdao Municipal Hospital Affiliated to Qingdao University, Qingdao 266000, China

ZHAO Hongfei Department of Radiology, Qingdao Municipal Hospital Affiliated to Qingdao University, Qingdao 266000, China

*Correspondence to: Wang GH, E-mail: wangguohua89@163.com

Conflicts of interest   None.

Received  2019-08-31
Accepted  2019-11-21
DOI: 10.12015/issn.1674-8034.2020.01.006
Cite this article as: Wang HT, Zhao XK, Wang GH, et al. The research value of quantitative study of parotid gland fat infiltration in early Sjogren's syndrome patients by using 3.0 T MR IDEAL-IQ sequence. Chin J Magn Reson Imaging, 2020, 11(1): 25-28. DOI:10.12015/issn.1674-8034.2020.01.006.

[1]
Fox RI. Sjogren's syndrome. Lancet. 2005, 366(9482): 321-331.
[2]
丁长伟，刘东武，薛红霞，等．干燥综合征的腮腺CT表现．中国临床医学影像杂志, 2015, 26(5): 317-320.
[3]
Shiboski CH, Shiboski SC, Seror R, et al. 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for primary Sjogren's syndrome: a consensus and data-driven methodology involving three international patient cohorts. Ann Rheum Dis, 2017, 76(1): 9-16.
[4]
Regier M, Ries T, Arndt C, et al. Sjogren's syndrome of the parotid gland: value of diffusion-weighted echo-planar MRI for diagnosis at an early stage based on MR sialography grading in comparison with healthy volunteers. Rofo, 2009, 181(3): 242-248.
[5]
陈志晔，李金锋，马林．干燥综合征患者腮腺扩散加权成像研究．中国医学影像学杂志, 2013, 21(3): 181-183.
[6]
Jonsson R, Vogelsang P, Volchenkov R, et al. The complexity of Sjogren's syndrome: novel aspects on pathogenesis. Immunol Lett, 2011, 141(1): 1-9.
[7]
Shiboski SC, Shiboski CH, Criswell L, et al. American College of Rheumatology classification criteria for Sjogren's syndrome: a data-driven, expert consensus approach in the Sjogren's international collaborative clinical alliance cohort. Arthritis Care Res (Hoboken), 2012, 64(4): 475-487.
[8]
Mahne A, El-Haddad G, Alavi A, et al. Assessment of age-related morphological and functional changes of selected structures of the head and neck by computed tomography, magnetic resonance imaging, and positron emission tomography. Semin Nucl Med, 2007, 37(2): 88-102.
[9]
Morimoto Y, Habu M, Tomoyose T, et al. Dynamic magnetic resonance sialography as a new diagnostic technique for patients with Sjogren's syndrome. Oral Dis, 2006, 12(4): 408-414.
[10]
Yokosawa M, Tsuboi H, Nasu K, et al. Usefulness of MR imaging of the parotid glands in patients with secondary Sjogren's syndrome associated with rheumatoid arthritis. Mod Rheumatol, 2015, 25(3): 415-420.
[11]
Chang HC, Juan CJ, Chiu HC, et al. Parotid fat contents in healthy subjects evaluated with iterative decomposition with echo asymmetry and least squares fat-water separation. Radiology, 2013, 267(3): 918-923.
[12]
胡磊，查云飞，林苑，等. IDEAL-IQ定量评价兔糖尿病模型椎体骨髓脂肪含量的可行性研究．磁共振成像, 2015, 6(12): 941-946.
[13]
Zhou N, Chu C, Dou X, et al. Early evaluation of radiation-induced parotid damage in patients with nasopharyngeal carcinoma by T2 mapping and mDIXON Quant imaging: initial findings. Radiat Oncol, 2018, 13(1): 22.
[14]
Chikui T, Yamashita Y, Kise Y, et al. Estimation of proton density fat fraction of the salivary gland. Br J Radiol, 2018, 91(1085): 20170671.
[15]
Su GY, Wang CB, Hu H, et al. Effect of laterality, gender, age and body mass index on the fat fraction of salivary glands in healthy volunteers: assessed using iterative decomposition of water and fat with echo asymmetry and least-squares estimation method. Dentomaxillofac Radiol, 2019, 48(3): 20180263.
[16]
Chang HC, Juan CJ, Chiu HC，等. MRI评价性别、年龄及体质量指数对正常腮腺腺体的脂肪含量和ADC值的影响．国际医学放射学杂志, 2014, 37(6): 593-594.

PREV Predictive value of temporal muscle thickness measurements on cranial magnetic resonance images in the prognosis of patients with primary glioblastoma
NEXT The accuracy of non enhanced MRA in evaluating the relationship between central lung cancer and pulmonary hilar and mediastinal vessels
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn