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• MRI in Acupuncture Study •
Effect of acupuncture on corticospinal tract remodeling in patients with stroke hemiplegia based on structural MRI
LI Jing  LIU Yongkang  LI Li  ZHOU Maodong  HOU Siyuan  LIU Shaowei  ZHU Xin 

Cite this article as: Li J, Liu YK, Li L, et al. Effect of acupuncture on corticospinal tract remodeling in patients with stroke hemiplegia based on structural MRI. Chin J Magn Reson Imaging, 2020, 11(2): 99-103. DOI:10.12015/issn.1674-8034.2020.02.005.


[Abstract] Objective: To investigate the effect of acupuncture combined with basic treatment on the remodeling of damaged corticospinal tract in hemiplegic patients with ischemic stroke by diffusion tensor imaging.Materials and Methods: 36 patients with ischemic stroke who met the criteria were randomly divided into control group and acupuncture group with 18 cases each group. The control group was treated with neurology-based Chinese and western medicine, and the acupuncture group was treated with acupuncture simultaneously. The mean value of fractional anisotropy (FA) of the entire segment of corticospinal tract and the FA value per 100 nodes of corticospinal tract in the two groups before and after treatment were compared.Results: (1) After treatment (at the end of 3 months), the mean value of FA with the affected corticospinal tract in the two groups was significantly higher than that before treatment (P<0.05); (2) Although the mean FA values of the entire CST in the acupuncture group and the control group was not significantly difference (P>0.05), the FA of every 100 nodes with the affected corticospinal tract in the acupuncture group and the control group were further compared after treatment, it was found that the two segments along the tract profiles had significant differences (P<0.05, FDR corrected) between two groups, which mainly distributed in the middle segment (50—60th point) and the top segment (90—100th point).Conclusions: Acupuncture can effectively promote the structural remodeling of corticospinal tract in patients with ischemic stroke, and provide objective imaging evidence for clinical application of acupuncture to improve hemiplegia.
[Keywords] acupuncture；stroke；diffusion tensor imaging；corticospinal tract；structural remodeling；magnetic resonance imaging

LI Jing Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China

LIU Yongkang Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China

LI Li Department of Neurology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China

ZHOU Maodong Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China

HOU Siyuan Department of Acupuncture and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China

LIU Shaowei Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China

ZHU Xin* Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China

*Correspondence to: Zhu X, E-mail: 66zhuxin@163.com

Conflicts of interest   None.

Received  2019-12-03
Accepted  2020-01-08
DOI: 10.12015/issn.1674-8034.2020.02.005
Cite this article as: Li J, Liu YK, Li L, et al. Effect of acupuncture on corticospinal tract remodeling in patients with stroke hemiplegia based on structural MRI. Chin J Magn Reson Imaging, 2020, 11(2): 99-103. DOI:10.12015/issn.1674-8034.2020.02.005.

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