Share：
Share this content in WeChat
X
[Chinese][PDF]98075
• Clinical Article •
The comparation of magnetic resonance spectroscopy using different sequence parameters in the prognosis of acute cerebral infarction
SHANG Wenwen  JIANG Liang  XUE Hailin  XUE Lian 

Cite this article as: Shang WW, Jiang L, Xue HL, et al. The comparation of magnetic resonance spectroscopy using different sequence parameters in the prognosis of acute cerebral infarction. Chin J Magn Reson Imaging, 2020, 11(2): 104-108. DOI:10.12015/issn.1674-8034.2020.02.006.


[Abstract] Objective: To investigate the clinical application value of magnetic resonance spectroscopy (MRS) in the treatment of acute cerebral infarction by using PRESS sequence-long echo time and STEAM sequence-short echo time scan.Materials and Methods: 27 patients with acute cerebral infarction were scanned by regular magnetic resonance and magnetic resonance spectroscopy using both PRESS sequence-long echo time and STEAM sequence-short echo time. Then the changes of metabolites on the infarct side and its correlation with mRS after three months were analyzed statistically and the results of two different MRS scan ways were compared.Results: (1) The contentions of NAA, Cho, Cr and the ratios of NAA/Cr, Cho/Cr in the infraction region were detected changes by two different MRS scanning techniques, but there was no significant difference between the two scan results. Lac was detected in some patients using PRESS sequence-long echo time scan, while Lac and short T2 substances such as mI and Glx were detected in the STEAM sequence-short echo time scan. (2) There were significantly negatively correlation between the ratios of rNAA, NAA/Cr and mRS scale after 3 months by using PRESS sequence-long echo time and STEAM sequence-short echo time scan. (3) The receiver operating characteristic curve showed that the sensitivity of rNAA, rCr and NAA/Cr in the infraction region to predict the prognosis of patients with acute cerebral infarction were 88.9%, 66.7%, 77.8% and specificity were 80%, 80%, 60% by using STEAM sequence-short echo time scan; while the sensitivity of 57.1%, 28.6%, 57.1%, and specificity of 75%, 87.5%, 87.5% by using PRESS sequence-long echo time scan.Conclusions: There have good consistency between PRESS sequence-long echo and STEAM sequence-short echo scan, which can detect changes of metabolites to reflect pathological changes in infarct areas. However, STEAM sequence-short echo scan can detect more species of metabolite abnormalities, and is superior to PRESS long echo in predicting prognosis of acute cerebral infarction.
[Keywords] stroke；point resolved spectroscopy；stimulated echo acquisition mode；short echo time；long echo time；magnetic resonance spectroscopy

SHANG Wenwen School of Radiology, Jiangsu Vocational College of Medicine, Yancheng 224000, China

JIANG Liang Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

XUE Hailin Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

XUE Lian* Department of Radiology, Clifford Hospital, Guangzhou University of Chinese Medicine, Guangzhou 511495, China

*Correspondence to: Xue L, E-mail: xuelian-1982@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of High Level Backbone Major Construction Project of Higher Vocational Education in Jiangsu Province No. 2017JSGG163 Medical Science and Technology Development Project of Yancheng in 2016 No. YK2016052
Received  2019-07-25
Accepted  2019-10-18
DOI: 10.12015/issn.1674-8034.2020.02.006
Cite this article as: Shang WW, Jiang L, Xue HL, et al. The comparation of magnetic resonance spectroscopy using different sequence parameters in the prognosis of acute cerebral infarction. Chin J Magn Reson Imaging, 2020, 11(2): 104-108. DOI:10.12015/issn.1674-8034.2020.02.006.

[1]
Arnberg F, Lundberg J, Soderman M, et al. Image-guided method in the rat for inducing cortical or striatal infarction and for conteolling cerebral blood flow under MRI. Stroke, 2013, 43(9): 2437-2443.
[2]
Guo YL, Li SJ, Zhang ZP, et al. Parameters of diffusional kurtosis imaging for the diagnosis of acute cerebral infarction in different brain regions. Exp Ther Med, 2016, 12(2): 933-938.
[3]
Jiang Y, Zhou Y, Wang B, et al. Clinical research of scalp acupuncture combined with rehabilitation training treating patients with cerebral infarction in recovery period based on 1H-MRS. Rehabilit Med, 2016, 26(1): 10.
[4]
Carmelo P, Armando P. New techniques of 1H spectroscopy on the liver: Reworking of NMR sequences. Radiography, 2014, 1(7): 124-130.
[5]
Liu C, Dong Z, Xu L, et al. MR image features predicting hemorrhagic transformation in acute cerebral infarction: a multimodal study. Neuroradiology, 2015, 57(11): 1145-1152.
[6]
尚文文，殷信道，薛海林，等. MR波谱成像在超急性脑梗死溶栓治疗中的应用研究．磁共振成像, 2016, 7(5): 359-364.
[7]
Janik R, Lam T, Stanisz AM, et al. Magnetic resonance spectroscopy reveals oral Lactobacillus promotion of increases in brain GABA, N-acetyl aspartate and glutamate. Neuroimage, 2015, 125: 988.
[8]
Henneberger C, PaPouin T, Oliet SH, et al. Long-term potentiation depends on release of D-serine from astrocytes. Nature, 2010, 463(7278): 232-236.
[9]
黄明明，曹笑婉，沈桂权，等．应用3.0 T 1H-MRS技术纵向评估血管性认知障碍大鼠脑内代谢物改变．磁共振成像, 2017, 8(9): 691-696.
[10]
Krishna A, Li An, Erica C, et al. Multivoxel MR spectroscopy in acute ischemic stroke comparison to the stroke protocol MRI. Stroke, 2012, 43(11): 2962-2967.
[11]
程流泉，蔡幼铨，高元桂，等．脑质子磁共振波谱检查PRESS和STEAM序列的对比．解放军医学杂志, 2000, 25(5): 349-352.
[12]
Kuo YT, Li CW, Chen CY, et al. In vivo proton magnetic resonance spectroscopy of large focal hepatic lesions and metabolite change of hepatocellular carcinoma before and after transcatheter arterial chemoembolization using3.0 T MR scanner 2004. J Magn Reson Imaging, 2004, 19(5): 859-604.
[13]
颜荣华，肖恩华．兔肝VX2瘤活体二维多体素1H-MRS成像STEAM和PRESS序列的比较.临床放射学杂志, 2008, 27(2): 273-277.
[14]
陈璇，李咏梅，欧阳羽，等．不同回波时间氢质子磁共振波谱多体素技术检出多发性硬化病灶和看似正常脑白质区．中国医学影像技术, 2011, 27(1): 32-36.
[15]
张冰，朱斌，郑凯尔，等．脑梗死1H-MRS不同序列的对比研究．放射学实践, 2002, 17(6): 461-463.
[16]
Mullins PG, Chen H, Xu J, et al. Comparative reliability of proton spectroscopy techniques designed to improve detection of J-coupled metabolites. Magn Reson Med, 2008, 60(4): 964-969.

PREV Effect of acupuncture on corticospinal tract remodeling in patients with stroke hemiplegia based on structural MRI
NEXT Application of HR-MRI in middle cerebral atherosclerotic plaque and characteristic analysis of lenticulostriate artery
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn