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• Clinical Article •
Differential diagnosis of breast medullary carcinoma and fibroadenoma by MRI
LI Yancui  ZHANG Ling  LIANG Wen  WANG Haili  PENG Ruchen 

Cite this article as: Li YC, Zhang L, Liang W, et al. Differential diagnosis of breast medullary carcinoma and fibroadenoma by MRI. Chin J Magn Reson Imaging, 2020, 11(2): 124-128. DOI:10.12015/issn.1674-8034.2020.02.010.


[Abstract] Objective: To explore the value of MRI in the diagnosis of breast medullary and fibroadenoma.Materials and Methods: Data of 9 cases of breast medullary cancer and 15 cases of fibroadenoma confirmed by pathology were retrospectively analyzed and compared. Evaluation the differential diagnostic performance of the ADCmean and the first order features of radiomics based on apparent diffusion coefficient (ADC) maps reconstructed in conventional diffusion-weighted images (DWI) of the cases.Results: The age of patients in medullary carcinoma group was older than that of fibroadenoma group (t=2.446, P=0.022). The maximum diameter of lesions in medullary carcinoma group was larger than that in fibroadenoma group (t=2.254, P=0.033). There were differences in lesion morphology, enhancement characteristics, necrosis and cystic degeneration, signal intensity of plain T2WI lesions, signal intensity of DWI lesions and time-signal intensity curve (TIC) types between the two groups. There are statistically difference in ADCmean between the two groups. Through first order features analysis based on ADC map, Correlation, Energy, Homogeneity, Mean, Standard_Deviation, Entropy, Variance, Kurtosis, IDM demonstrated significant difference between breast medullary carcinoma and breast fibro-adenoma group differences.Conclusions: MRI features of lesions are helpful in differentiating medullary breast cancer from fibroadenoma. ADCmean and some first-order features of lesions have high value in the differential diagnosis.
[Keywords] magnetic resonance imaging；medullary breast carcinoma；breast fibroadenoma；first-order statistics

LI Yancui Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing 101149, China

ZHANG Ling Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing 101149, China

LIANG Wen Department of Ultrasonography, Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing 101149, China

WANG Haili Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing 101149, China

PENG Ruchen* Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, Beijing 101149, China

*Correspondence to: Peng RC, E-mail: 13501271260@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Beijing Tongzhou Science and Technology Plan Project No.KJ2019CX012-08
Received  2019-09-06
Accepted  2019-11-29
DOI: 10.12015/issn.1674-8034.2020.02.010
Cite this article as: Li YC, Zhang L, Liang W, et al. Differential diagnosis of breast medullary carcinoma and fibroadenoma by MRI. Chin J Magn Reson Imaging, 2020, 11(2): 124-128. DOI:10.12015/issn.1674-8034.2020.02.010.

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