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• Clinical Article •
Study of the default mode network in delayed encephalopathy after acute carbon monoxide poisoning using independent component analysis
WU Kaifu  HE Laichang  TAN Yongming 

Cite this article as: Wu KF, He LC, Tan YM. Study of the default mode network in delayed encephalopathy after acute carbon monoxide poisoning using independent component analysis. Chin J Magn Reson Imaging, 2020, 11(3): 190-194. DOI:10.12015/issn.1674-8034.2020.03.006.


[Abstract] Objective: To explore the characteristic of brain function damage in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) by using the technique of resting-state functional magnetic resonance imaging technology.Materials and Methods: Twenty-two DEACMP patients and 22 age-, gender- and education-matched healthy controls were studied with resting-state fMRI scan. Independent component analysis (ICA) was employed for the data analysis. One-sample t-test was performed to make the mask of networks components. And then two-sample t-test was performed to explore the difference between DEACMP patients and healthy controls in functional networks. The 24-item Hamilton Rating Scale for depression (HAMD-24), Hamilton Anxiety Rating Scale (HAMA) and Mini-mental State Examination (MMSE) were performed to assess the clinical symptoms.Results: The resting-state mask of default mode network (DMN) was obtained by data analysis in groups. It was found that the DMN functional connectivity in DEACMP patients was higher than that of healthy controls in frontal sup medial, precuneus and angular left.Conclusions: Patients with DEACMP has DMN abnormalities, mainly presenting increased functional connections. Certain cognitive function compensation might occur in those patients.
[Keywords] carbon monoxide poisoning；delayed encephalopathy；magnetic resonance imaging

WU Kaifu Department of Radiology, the First Affiliated Hospital of Nanchang University, Jiangxi Province, Nanchang 330006, China

HE Laichang Department of Radiology, the First Affiliated Hospital of Nanchang University, Jiangxi Province, Nanchang 330006, China

TAN Yongming* Department of Radiology, the First Affiliated Hospital of Nanchang University, Jiangxi Province, Nanchang 330006, China

*Correspondence to: Tan YM, E-mail: 627871378@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by the National Natural Science Found No. 81460329 Natural Science Foundation of Jiangxi Province No. 20192ACBL20039, 20181BAB205063
Received  2019-09-26
Accepted  2019-11-22
DOI: 10.12015/issn.1674-8034.2020.03.006
Cite this article as: Wu KF, He LC, Tan YM. Study of the default mode network in delayed encephalopathy after acute carbon monoxide poisoning using independent component analysis. Chin J Magn Reson Imaging, 2020, 11(3): 190-194. DOI:10.12015/issn.1674-8034.2020.03.006.

[1]
Xiang W, Xue H, Wang B, et al. Combined application of dexamethasone and hyperbaric oxygen therapy yields better efficacy for patients with delayed encephalopathy after acute carbon monoxide poisoning. Drug Des Devel Ther, 2017, 11: 513-519.
[2]
Yoshiike T, Nishida M, Yagishita K, et al. Altered sleep spindle in delayed encephalopathy after acute carbon monoxide poisoning. J Clin Sleep Med, 2016, 12(6): 913-915.
[3]
汪涛．急性一氧化碳中毒迟发性脑病的临床分析．中国现代药物应用, 2019, 13(12): 19-21.
[4]
Ernst A, Zibrak J D. Carbon monoxide poisoning. Critical Care Clin, 2012, 28(4): 537-548.
[5]
武小娟，李旭，刘红新，等．急性一氧化碳中毒发生迟发性脑病的相关因素．预防医学, 2017, 29(1): 86-87.
[6]
David S, Lahar M. The syndrome of delayed post-hypoxic leukoencephalopathy. Neurorehabilitation, 2010, 26(1): 65-72.
[7]
Frederik B, Sven H, Rombouts SA. Resting-state functional MR imaging: a new window to the brain. Radiology, 2014, 272(1): 29-49.
[8]
史振威．独立成分分析的若干算法及其应用研究．大连理工大学, 2005.
[9]
Beckmann CF, Marilena DL, Devlin JT, et al. Investigations into restingstate connectivity using independent component analysis. Philos Trans R Soc Lond B Biol Sci, 2005, 360(1457): 1001-1013.
[10]
Rosazza C, Minati L, Ghielmetti F, et al. Functional connectivity during resting-state functional MR imaging: study of the correspondence between independent component analysis and region-of-interest-based methods. AJNR Am J Neuroradiol, 2012, 33(1): 180-187.
[11]
葛均波，徐永健．内科学. 8版．北京：人民卫生出版社, 2013: 906-909.
[12]
Calhoun VD, Adali T, Pearlson GD, et al. A method for making group inferences from functional MRI data using independent component analysis. Human Brain Mapping, 2010, 14(3): 140.
[13]
Friston KJ. Functional and effective connectivity in neuroimaging: a synthesis. Human Brain Mapping, 1994, 2(1-2): 56-78.
[14]
张佩瑶，徐琴，王君，等．缺血性卒中后抑郁患者静息状态下默认网络功能连接的研究．磁共振成像, 2017, 8(6): 401-407.
[15]
Raichle ME, Macleod AM, Snyder AZ, et al. A default mode of brain function. Proc Natl Acad Sci U S A, 2001, 98(2): 676-682.
[16]
Mazoyer B, Zago L, Mellet E, et al. Cortical networks for working memory and executive functions sustain the conscious resting state in man. Brain Res Bull, 2001, 54(3): 287-298.
[17]
Nathan RS, Grady CL. Patterns of brain activity supporting autobiographical memory, prospection, and theory of mind, and their relationship to the default mode network. J Cogn Neurosci, 2010, 22(6): 1112-1123.
[18]
Mohammad D, Foster BL, Sharmin N, et al. Differential electrophysiological response during rest, self-referential, and non-self-referential tasks in human posteromedial cortex. Proc Natl Acad Sci U S A, 2011, 108(7): 3023-3028.
[19]
Ouchi Y, Kikuchi M. A review of the default mode network in aging and dementia based on molecular imaging. Rev Neurosci, 2012, 23(3): 263-268.
[20]
Morcom AM, Fletcher PC. Does the brain have a baseline? Why we should be resisting a rest. Neuroimage, 2007, 37(4): 1073-1082.
[21]
Greicius MD, Kaustubh S, Vinod M, et al. Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex, 2009,19(1): 72-78.
[22]
Hutchison RM, Leung LS, Mirsattari SM, et al. Resting-state networks in the macaque at 7 T. Neuroimage, 2011, 56(3): 1546-1555.
[23]
Dimitrova A, Kolb FP, Elles HG, et al. Cerebellar activation during leg withdrawal reflex conditioning: an fMRI study. Clin Neurophysiol, 2004, 115(4): 849-857.
[24]
Eun-Jung P, Young-Gi M, Gi-Woon K, et al. Pathophysiology of brain injuries in acute carbon monoxide poisoning: a novel hypothesis. Med Hypotheses, 2014, 83(2): 186-189.
[25]
Pang L, Bian M, Zang XX, et al. Neuroprotective effects of erythropoietin in patients with carbon monoxide poisoning. J Biochem Mol Toxicol, 2013, 27(5): 266-271.
[26]
Yanagiha K, Ishii K, Tamaoka A. Acetylcholinesterase inhibitor treatment alleviated cognitive impairment caused by delayed encephalopathy due to carbon monoxide poisoning: two case reports and a review of the literature. Medicine, 2017, 96(8): e6125.
[27]
Amodio D, Frith C. Meeting of minds: the medial frontal cortex and social cognition. Nat Rev Neuroscie, 2006, 7(4): 268-277.
[28]
Snyder HR. Major depressive disorder is associated with broad impairments on neuropsychological measures of executive function: a meta-analysis and review. Psychological Bulletin, 2013, 139(1): 81-132.
[29]
Yang YL, Raine A. Prefrontal structural and functional brain imaging findings in antisocial, violent, and psychopathic individuals: a meta-analysis. Psychiatry Res, 2009, 174(2): 81-88.
[30]
Cavanna AE, Trimble MR. The precuneus: a review of its functional anatomy and behavioural correlates. Brain, 2006, 129(3): 564-583.
[31]
Dardo T, Gene-Jack W, Volkow ND. Energetic cost of brain functional connectivity. Proc Natl Acad Sci U S A, 2013, 110(33): 13642-13647.
[32]
Binder JR, Desai RH, Graves WW, et al. Where is the semantic system? A critical review and meta-analysis of 120 functional neuroimaging studies. Cereb Cortex, 2009, 19(12): 2767-2796.
[33]
Oitzl MS, Champagne DL, Van DVR, et al. Brain development under stress: hypotheses of glucocorticoid actions revisited. Neurosci Biobehav Rev, 2010, 34(6): 853-866.

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