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• Clinical Article •
A research of the default mode network in patients with chronic neck and shoulder pain of cervical spondylotic radiculopathy
CHEN Yi  YU Chengxin  LI Bo  JI Tingting 

Cite this article as: Chen Y, Yu CX, Li B, et al. A research of the default mode network in patients with chronic neck and shoulder pain of cervical spondylotic radiculopathy. Chin J Magn Reson Imaging, 2020, 11(3): 211-215. DOI:10.12015/issn.1674-8034.2020.03.010.


[Abstract] Objective: To explore the changes of DMN functional connections in cervical spondylotic radiculopathy (CSR) patients with chronic neck and shoulder pain by independent component analysis (ICA).Materials and Methods: Twenty-nine subjects were scanned with conventional magnetic resonance, high resolution 3D-T1 structural imaging and resting state functional magnetic resonance (rs-fMRI) using 3.0 T MR. VAS was performed at the end of the scan. ICA was used to separate and extract the DMN. The changes of the DMN functional connections between the two groups were compared and analyzed. Pearson correlation analysis was made between the functional connections strength of different brain regions and VAS score.Results: Compared with the normal group, the functional connections of thalamus, hippocampus, basal nucleus, left middle temporal gyrus and anterior cuneiform lobe decreased, and the functional connections of right superior temporal gyrus increased in patients. There was a negative correlation between hippocampal functional connections and VAS score (r=-0.546, P=0.043).Conclusions: The changes of functional connections of DMN in patients with chronic pain of CSR may be related to the changes of cognitive pain processing, emotional processing and memory function in patients with chronic pain of CSR.
[Keywords] cervical spondylotic radiculopathy；default mode network；independent component analysis；functional connection

CHEN Yi The First College of Clinical Medical Science, China Three Gorges University, Hubei Provincei, Yichang 443000, China

YU Chengxin* The First College of Clinical Medical Science, China Three Gorges University, Hubei Provincei, Yichang 443000, China

LI Bo The First College of Clinical Medical Science, China Three Gorges University, Hubei Provincei, Yichang 443000, China

JI Tingting The First College of Clinical Medical Science, China Three Gorges University, Hubei Provincei, Yichang 443000, China

*Correspondence to: Yu CX, E-mail: ycyucx@163.com

Conflicts of interest   None.

Received  2019-10-14
Accepted  2019-11-21
DOI: 10.12015/issn.1674-8034.2020.03.010
Cite this article as: Chen Y, Yu CX, Li B, et al. A research of the default mode network in patients with chronic neck and shoulder pain of cervical spondylotic radiculopathy. Chin J Magn Reson Imaging, 2020, 11(3): 211-215. DOI:10.12015/issn.1674-8034.2020.03.010.

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