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Advances in imaging studies of senile depression
LI Xiaoling  YAO Chunli  WANG Feng  CAO Danna  ZHANG Kunyu  LIU Xiaohui  CAI Lina  JIANG Xiaoxu  NIE Shouping 

Cite this article as: Li XL, Yao CL, Wang F, et al. Advances in imaging studies of senile depression. Chin J Magn Reson Imaging, 2020, 11(3): 228-231. DOI:10.12015/issn.1674-8034.2020.03.015.


[Abstract] Late-life depression (LLD), as a heterogeneous syndrome, is a common clinical psychiatric disorder. At present, the pathophysiological mechanism of senile depression is not clear, and many previous studies often emphasize that its occurrence is related to vascular damage, nerve inflammation and other changes. With the development of imaging technology, more and more neuroimaging studies have shown that the pathogenesis of senile depression is closely related to changes in brain structure, brain function and brain metabolism. As a non-invasive examination method, imaging technology is becoming more and more mature. Compared with the widely used clinical diagnosis methods, it can provide more visual evidence and reduce the error caused by subjective factors. Now, imaging has been widely used in the study of neurobiological mechanism of senile depression, which provides new ideas and treatment methods for the diagnosis, treatment and prognosis evaluation of senile depression. This article will review the study of imaging in senile depression.
[Keywords] geriatric depression；imaging；brain structure；brain function；cerebral metabolic

LI Xiaoling Department of CT and Magnetic Resonance, First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin 150040, China

YAO Chunli Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

WANG Feng Department of CT and Magnetic Resonance, First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin 150040, China; Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

CAO Danna* Department of CT and Magnetic Resonance, First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin 150040, China; Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

ZHANG Kunyu Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

LIU Xiaohui Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

CAI Lina Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

JIANG Xiaoxu Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

NIE Shouping Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

*Corresponding to: Cao DN, E-mail: hljanna@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  National Natural Science Foundation of China No. 81973930, 81373714 Heilongjiang Province Natural Science Foundation Surface Project No. H2016081 Harbin Science and Technology Innovation Outstanding Academic Leaders Fund No. 2016RAXYJ096 Ministry of Education "Chunhui Plan" No. Z2009-1-15030 Harbin Science and Technology Innovation Talent Special Fund Project No. 2017RAQXJ180 Research Fund Project of Heilongjiang University of Traditional Chinese Medicine No. 201704 Innovative Research Project for Graduate Students of Heilongjiang University of Traditional Chinese Medicine No. 2019yjscx024
Received  2019-11-18
Accepted  2020-02-12
DOI: 10.12015/issn.1674-8034.2020.03.015
Cite this article as: Li XL, Yao CL, Wang F, et al. Advances in imaging studies of senile depression. Chin J Magn Reson Imaging, 2020, 11(3): 228-231. DOI:10.12015/issn.1674-8034.2020.03.015.

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