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• Review •
Value of the central vein sign in multiple sclerosis
Minawaer• Yimiti  Mayinuer• Maimaiti 

Cite this article as: Minawaer•Yimiti, Mayinuer•Maimaiti. Value of the central vein sign in multiple sclerosis. Chin J Magn Reson Imaging, 2020, 11(3): 232-234. DOI:10.12015/issn.1674-8034.2020.03.016.


[Abstract] The diagnosis of multiple sclerosis (MS) is often difficult, timely and correct diagnosis plays an important role in the early treatment and prognosis of the disease.In multiple sclerosis, magnetic resonance imaging (MRI) is a sensitive tool for detecting white matter lesions, but its diagnostic specificity is still suboptimal; ambiguous cases are frequent in clinical practice. Detection of perivenular lesions in the brain (the "central vein sign, CVS" ) improves the pathological specificity of MS diagnosis, and the discovery of central vein sign is expected to be a marker for the diagnosis of MS. Recent studies have demonstrated that the CVS may have the ability to accurately differentiateMSfrom its mimics. This review will systematically analyze the characteristics of CVS of MRI and its role in the diagnosis and differentiation of MS to provide important clues for the clinical diagnosis of MS.
[Keywords] central vein sign；magnetic resonance imaging；multiple sclerosis

Minawaer• Yimiti Xinjiang Medical University, Urumqi 830001, China

Mayinuer• Maimaiti* Xinjiang People's Hospital, Neurology department, Urumqi 830001, China

*Corresponding to: Mayinuer•Maimaiti, E-mail: maiynur2@163.com

Conflicts of interest   None.

Received  2019-09-12
Accepted  2020-02-12
DOI: 10.12015/issn.1674-8034.2020.03.016
Cite this article as: Minawaer•Yimiti, Mayinuer•Maimaiti. Value of the central vein sign in multiple sclerosis. Chin J Magn Reson Imaging, 2020, 11(3): 232-234. DOI:10.12015/issn.1674-8034.2020.03.016.

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