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• Clinical Article •
Resting-state functional MRI to assess the brain function before and after the operation of children with cerebral palsy
AIJIEERGULI• MAIHESUMU  SONG Juan  XIE Chao  WANG Yunling 

Cite this article as: AIJIEERGULI•MAIHESUMU, Song J, Xie C, et al. Resting-state functional MRI to assess the brain function before and after the operation of children with cerebral palsy. Chin J Magn Reson Imaging, 2020, 11(4): 259-263. DOI:10.12015/issn.1674-8034.2020.04.004.


[Abstract] Objective: To investigate the effect of cervical perivascular sympathectomy on brain function in children with cerebral palsy by using resting-state functional MRI (rs-fMRI).Materials and Methods: Twenty-one children with hemiplegic cerebral palsy underwent routine MRI and rs-fMRI scanning before and after operation. Data processing assistant for rs-fMRI (DPARSF) software package was used to process. Paired sample t-test was performed to compare the differences of amplitude of low-frequency fluctuation (ALFF) and regional homogeneity (ReHo) values before and after the operation.Results: Compared with pre-operation, increased ALFF and (or) ReHo was found in the multiple brain regions of the affected side, in the normal side, the ALFF increased in cerebellum anterior lobe (P<0.05). Decreased ALFF and (or) ReHo was found in multiple brain regions of the normal side, in the affected side, ALFF and ReHo decreased in superior frontal gyrus.Conclusions: The results of rs-fMRI show that cervical perivascular symphathectomy improve the spontaneous low-frequency oscillation activity of neurons in related areas, and strengthen the functional connection of relevant brain regions.
[Keywords] amplitude of low-frequency fluctuation；regional homogeneity；functional magnetic resonance imaging；cerebral palsy

AIJIEERGULI• MAIHESUMU Department of Radiology, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

SONG Juan Department of Radiology, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

XIE Chao Department of Radiology, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

WANG Yunling* Department of Radiology, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

*Correspondence to: Wang YL, E-mail:1079806994@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No.81660202
Received  2019-10-06
Accepted  2019-11-29
DOI: 10.12015/issn.1674-8034.2020.04.004
Cite this article as: AIJIEERGULI•MAIHESUMU, Song J, Xie C, et al. Resting-state functional MRI to assess the brain function before and after the operation of children with cerebral palsy. Chin J Magn Reson Imaging, 2020, 11(4): 259-263. DOI:10.12015/issn.1674-8034.2020.04.004.

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