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• Clinical Article •
The value of collateral vessels on magnetic resonance angiography in the prognosis of stroke patients after mechanical thrombectomy associated with clinical outcomes
CHEN Guanghao  QIU Jianbo  ZHENG Shaoqing  YIN Xindao  PENG Mingyang  MA Yuehu 

Cite this article as: Chen GH, Qiu JB, Zheng SQ, et al. The value of collateral vessels on magnetic resonance angiography in the prognosis of stroke patients after mechanical thrombectomy associated with clinical outcomes. Chin J Magn Reson Imaging, 2020, 11(4): 270-274. DOI:10.12015/issn.1674-8034.2020.04.006.


[Abstract] Objective: To evaluate the association between the collateral vessels on magnetic resonance angiography (MRA) and clinical outcome in acute stroke patients after mechanical thrombectomy.Materials and Methods: In this prospective study, acute stroke patients who received mechanical thrombectomy therapy were evaluated. All patients underwent head MRI plain scan and MRA examination before therapy and after therapy. Functional outcome at 3 months was assessed by using the modified Rankin Scale (mRS). mRS 0—2 is good functional outcome group and 3—6 is poor functional outcome group. Statistical methods were used to analyze the sylvian fissure and the leptomeningeal convexity differences between two groups.Results: Of 55 patients, cases with insufficient collateral circulation at the sylvian fissure (52) and leptomeningeal convexity (45) showed that the NIHSS score at arrival (10.06±4.65 vs 14.25±4.91; P=0.006) and preoperative infarct volume (13.61±10.99 vs 59.80±92.74; P=0.006) were significantly lower in mRS score of 0—2 than that in mRS score of 3-6. Multivariate testing revealed age and collateral status at the leptomeningeal convexity were independent of the clinical outcome at 3 months after stroke (OR=1.094, 95%CI=1.025—1.168, P=0.007; OR=9.542, 95%CI=1.812—50.245, P=0.008 respectively). The change of infarct volume in the group with mRS score of 0-2 (preoperative vs postoperative: 14.15±10.73 vs 21.39±17.41) was smaller than that with mRS score of 3- 6 (preoperative vs postoperative: 16.88±16.64 vs 57.27±56.67). While multivariate logistic models showed that postoperative infarct volume was non-significant in predicting the clinical outcome after stroke (OR=1.094, 95%CI=1.025—1.168; P=0.154).Conclusions: MRA can be used to evaluate the functional outcome in patients with stroke, especially the extent of collateral circulation at the leptomeningeal convexity may be useful for predicting the functional recovery. While the relationship between postoperative infarct volume and clinical outcome still requires for further study.
[Keywords] stroke；collateral vessels；mechanical thrombectomy；magnetic resonance angiography；magnetic resonance imaging

CHEN Guanghao Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

QIU Jianbo Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

ZHENG Shaoqing Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

YIN Xindao Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

PENG Mingyang Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

MA Yuehu* Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

*Correspondence to: Ma YH, E-mail: mayuehu1976@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Jiangsu Science and Technology Development Project No. BE2017614
Received  2019-11-22
Accepted  2019-12-31
DOI: 10.12015/issn.1674-8034.2020.04.006
Cite this article as: Chen GH, Qiu JB, Zheng SQ, et al. The value of collateral vessels on magnetic resonance angiography in the prognosis of stroke patients after mechanical thrombectomy associated with clinical outcomes. Chin J Magn Reson Imaging, 2020, 11(4): 270-274. DOI:10.12015/issn.1674-8034.2020.04.006.

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