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• Clinical Article •
Cardiovascular magnetic resonance feature tracking in the quantitative assessment of early left atrial dysfunction in hypertensive patients
CHEN Xiuyu  LI Lu  SONG Yanyan  YIN Gang  ZHAO Shihua 

Cite this article as: Chen XY, Li L, Song YY, et al. Cardiovascular magnetic resonance feature tracking in the quantitative assessment of early left atrial dysfunction in hypertensive patients. Chin J Magn Reson Imaging, 2020, 11(4): 281-285. DOI:10.12015/issn.1674-8034.2020.04.008.


[Abstract] Objective: To evaluate the early left atrial (LA) dysfunction in hypertensive patients by using cardiovascular magnetic resonance feature tracking (CMR-FT).Materials and Methods: Thirty patients diagnosed with hypertension in our hospital from January 2012 to December 2013 were consecutively recruited and all patients underwent CMR examinations. Patients with LA enlargement, left ventricular ejection fraction (LVEF) <50% and other cardiovascular diseases were excluded. Thirty age- and sex-matched healthy subjects were included as controls. LA strain analysis was performed both on the two- and four-chamber cine images. LA reservoir, conduit and contractile functional parameters including ejection fraction (EF), strain and strain rate were collected respectively. All the clinical and CMR parameters were compared between the two groups.Results: The mean age was 45.93±10.38 yrs, 66.6%(20/30) were males. In hypertensive patients, body surface area, body mass index and resting systolic/diastolic blood pressure were all significantly higher than those of the controls. Similar results were observed in terms of LVEF [(64.08±7.99)% vs (59.89±4.59)%, P=0.018] and LV mass [(61.14±10.59) g/m2 vs (37.93±10.45) g/m2, P<0.001]. Regarding the LA parameters, there were no significant differences in terms of the LA maximum volume, pre-atrial contractile LA volume and minimum volume index between the two groups. In hypertensive patients, the LA EF and strain in both reservoir and conduit phases were significantly impaired, while no statistical differences were observed in LA contractile parameters.Conclusions: CMR-FT technique could be used to detect LA dysfunction before LA enlargement in hypertensive patients. In those patients, the LA reservoir and conduit function were impaired while the contractile function was preserved.
[Keywords] magnetic resonance imaging；hypertension；left atrial function；dysfunction

CHEN Xiuyu Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

LI Lu Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

SONG Yanyan Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

YIN Gang Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

ZHAO Shihua* Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

*Correspondence to: Zhao SH, E-mail: cjr.zhaoshihua@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Youth Foundation of China No. 81701659 International Cooperation and Exchange Program of National Natural Science Foundation of China No. 81620108015
Received  2019-12-10
Accepted  2020-03-02
DOI: 10.12015/issn.1674-8034.2020.04.008
Cite this article as: Chen XY, Li L, Song YY, et al. Cardiovascular magnetic resonance feature tracking in the quantitative assessment of early left atrial dysfunction in hypertensive patients. Chin J Magn Reson Imaging, 2020, 11(4): 281-285. DOI:10.12015/issn.1674-8034.2020.04.008.

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