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• Clinical Article •
Cardiovascular magnetic resonance feature tracking in the quantitative assessment of early left atrial dysfunction in hypertensive patients
CHEN Xiuyu  LI Lu  SONG Yanyan  YIN Gang  ZHAO Shihua 

Cite this article as: Chen XY, Li L, Song YY, et al. Cardiovascular magnetic resonance feature tracking in the quantitative assessment of early left atrial dysfunction in hypertensive patients. Chin J Magn Reson Imaging, 2020, 11(4): 281-285. DOI:10.12015/issn.1674-8034.2020.04.008.


[Abstract] Objective: To evaluate the early left atrial (LA) dysfunction in hypertensive patients by using cardiovascular magnetic resonance feature tracking (CMR-FT).Materials and Methods: Thirty patients diagnosed with hypertension in our hospital from January 2012 to December 2013 were consecutively recruited and all patients underwent CMR examinations. Patients with LA enlargement, left ventricular ejection fraction (LVEF) <50% and other cardiovascular diseases were excluded. Thirty age- and sex-matched healthy subjects were included as controls. LA strain analysis was performed both on the two- and four-chamber cine images. LA reservoir, conduit and contractile functional parameters including ejection fraction (EF), strain and strain rate were collected respectively. All the clinical and CMR parameters were compared between the two groups.Results: The mean age was 45.93±10.38 yrs, 66.6%(20/30) were males. In hypertensive patients, body surface area, body mass index and resting systolic/diastolic blood pressure were all significantly higher than those of the controls. Similar results were observed in terms of LVEF [(64.08±7.99)% vs (59.89±4.59)%, P=0.018] and LV mass [(61.14±10.59) g/m2 vs (37.93±10.45) g/m2, P<0.001]. Regarding the LA parameters, there were no significant differences in terms of the LA maximum volume, pre-atrial contractile LA volume and minimum volume index between the two groups. In hypertensive patients, the LA EF and strain in both reservoir and conduit phases were significantly impaired, while no statistical differences were observed in LA contractile parameters.Conclusions: CMR-FT technique could be used to detect LA dysfunction before LA enlargement in hypertensive patients. In those patients, the LA reservoir and conduit function were impaired while the contractile function was preserved.
[Keywords] magnetic resonance imaging；hypertension；left atrial function；dysfunction

CHEN Xiuyu Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

LI Lu Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

SONG Yanyan Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

YIN Gang Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

ZHAO Shihua* Department of Magnetic Resonance Imaging, Fuwai Hospital, Beijing 100037, China

*Correspondence to: Zhao SH, E-mail: cjr.zhaoshihua@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Youth Foundation of China No. 81701659 International Cooperation and Exchange Program of National Natural Science Foundation of China No. 81620108015
Received  2019-12-10
Accepted  2020-03-02
DOI: 10.12015/issn.1674-8034.2020.04.008
Cite this article as: Chen XY, Li L, Song YY, et al. Cardiovascular magnetic resonance feature tracking in the quantitative assessment of early left atrial dysfunction in hypertensive patients. Chin J Magn Reson Imaging, 2020, 11(4): 281-285. DOI:10.12015/issn.1674-8034.2020.04.008.

[1]
Williams B, Mancia G, Spiering W, et al. 2018 ESC/ESH guidelines for the management of arterial hypertension. Eur Heart J, 2018, 39(33): 3021-3104.
[2]
Levy D, Garrison RJ, Savage DD, et al. Prognostic value of left ventricular diastolic dysfunction in a general population. J Am Heart Assoc, 2014, 3(3): e000789.
[3]
Kuznetsova T, Thijs L, Knez J, et al. Prognostic implications of echocardiographically determined left ventricular mass in the framingham heart study. N Engl J Med, 1990, 322(22): 1561-1566.
[4]
Moller JE, Hillis GS, Oh JK, et al. Left atrial volume: a powerful predictor of survival after acute myocardial infarction. Circulation, 2003, 107(17): 2207-2212.
[5]
Tsang TS, Barnes ME, Gersh BJ, et al. Left atrial volume as a morphophysiologic expression of left ventricular diastolic dysfunction and relation to cardiovascular risk burden. Am J Cardiol, 2002, 90(12): 1284-1289.
[6]
Miyoshi H, Oishi Y, Mizuguchi Y, et al. Early predictors of alterations in left atrial structure and function related to left ventricular dysfunction in asymptomatic patients with hypertension. J Am Soc Hypertens, 2013, 7(3): 206-215.
[7]
Yang L, Qiu Q, Fang SH. Evaluation of left atrial function in hypertensive patients with and without left ventricular hypertrophy using velocity vector imaging. Int J Cardiovasc Imaging, 2014, 30(8): 1465-1471.
[8]
Kowallick JT, Morton G, Lamata P, et al. Quantification of atrial dynamics using cardiovascular magnetic resonance: inter-study reproducibility. J Cardiovasc Magn Reson, 2015, 17: 36.
[9]
Obokata M, Nagata Y, Wu VC, et al. Direct comparison of cardiac magnetic resonance feature tracking and 2D/3D echocardiography speckle tracking for evaluation of global left ventricular strain. Eur Heart J Cardiovasc Imaging, 2016, 17(5): 525-532.
[10]
Olivotto I, Maron MS, Autore C, et al. Assessment and significance of left ventricular mass by cardiovascular magnetic resonance in hypertrophic cardiomyopathy. J Am Coll Cardiol, 2008, 52(7): 559-566.
[11]
Peng J, Zhao X, Zhao L, et al. Normal values of myocardial deformation assessed by cardiovascular magnetic resonance feature tracking in a healthy Chinese population: A multicenter study. Front Physiol, 2018, 9: 1181.
[12]
Soullier C, Niamkey JT, Ricci JE, et al. Hypertensive patients with left ventricular hypertrophy have global left atrial dysfunction and impaired atrio-ventricular coupling. J Hypertens, 2016, 34(8): 1615-1620.
[13]
Badran HM, Faheem N, Elnoamany MF, et al. Characterization of left atrial mechanics in hypertrophic cardiomyopathy and essential hypertension using vector velocity imaging. Echocardiography, 2015, 32(10): 1527-1538.
[14]
Xu TY, Sun JP, Lee AP, et al. Left atrial function as assessed by speckle-tracking echocardiography in hypertension. Medicine (Baltimore), 2015, 94(6): e526.
[15]
Kokubu N, Yuda S, Tsuchihashi K, et al. Noninvasive assessment of left atrial function by strain rate imaging in patients with hypertension: a possible beneficial effect of renin-angiotensin system inhibition on left atrial function. Hypertens Res, 2007, 30(1): 13-21.
[16]
Kuruvilla S, Janardhanan R, Antkowiak P, et al. Increased extracellular volume and altered mechanics are associated with LVH in hypertensive heart disease, not hypertension alone. JACC Cardiovasc Imaging, 2015, 8(2): 172-180.
[17]
Imai M, Ambale Venkatesh B, Samiei S, et al. Multi-ethnic study of atherosclerosis: association between left atrial function using tissue tracking from cine MR imaging and myocardial fibrosis. Radiology, 2014, 273(3): 703-713.

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