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• Clinical Article •
Cardiac magnetic resonance imaging in obstructive sleep apnea-hypopnea syndrome patients
YUAN Yue  BAO Haihua 

Cite this article as: Yuan Y, Bao HH. Cardiac magnetic resonance imaging in obstructive sleep apnea-hypopnea syndrome patients. Chin J Magn Reson Imaging, 2020, 11(4): 286-290. DOI:10.12015/issn.1674-8034.2020.04.009.


[Abstract] Objective: To investigate the changes of left ventricular function and myocardium in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), and carry out quantitative analysis of myocardial tissue by cardiac magnetic resonance imaging.Materials and Methods: Twenty-four male patients, aged 40—60 years old, and 25 normal adult male healthy volunteers, aged 40—60 years old, who met the 2011 revised OSAHS diagnostic criteria and were diagnosed as OSAHS after polysomnography (PSG) monitoring were selected. Perform the following sequence scans: Multi-temporal cine sequence based on gradient echo, modified look-locker inversion recovery (MOLLI) sequence contrast agent T1 mapping before injection, T2 mapping based on steady-state free-precession (SSFP), T1 scout sequence and MOLLI sequence contrast agent T1 mapping after injection. Left ventricular functional parameters [left ventricular ejection fraction (LVEF), left ventricular end diastolic volume (LVEDV), end systolic volume (LVESV), stroke volume (LVSV), cardiac output (LVCO), cardiac index (LVCI), left ventricular myocardial mass (LVM)], left ventricular myocardial T1 value, T2 value and ECV value were obtained.Results: (1) Cardiac function related parameters: LVEF, LVEDV, LVSV in OSAHS group were lower than those in normal, LVESV and LVM were higher than that in normal, and the difference was statistically significant (P<0.05); there was no significant difference in ESV, SV and CO between OSAHS and normal (P>0.05). (2) Histological parameters: T2 value of middle segment, apex segment and mean of left ventricular myocardium in OSAHS were higher than those in normal, the difference was statistically significant (P<0.05); the mean pre-contrast T1 and ECV values of left ventricle myocardium in OSAHS were higher than those in normal, but the difference was not statistically significant (P>0.05).Conclusions: (1) Cardiac magnetic resonance imaging technology can effectively evaluate the cardiac structure, function and the early changes of myocardium of OSAHS patients, which has an important clinical application value; (2) Left ventricular systolic and diastolic functions of OSAHS were both reduced differently degrees and myocardial quality was increased; (3) Acute inflammatory changes of different degrees in left ventricular myocardium of OSAHS occur.
[Keywords] obstructive sleep apnea-hypopnea syndrome；cardiac magnetic resonance；cardiac function；myocardial damage；magnetic resonance imaging

YUAN Yue Affiliated Hospital of Qinghai University, Xining 800001, China

BAO Haihua* Affiliated Hospital of Qinghai University, Xining 800001, China

*Correspondence to: Bao HH, E-mail: Baohelen2@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Science and Technology Program of Qinghai Science and Technology Department No. 2017-SF-158
Received  2019-10-29
Accepted  2019-12-31
DOI: 10.12015/issn.1674-8034.2020.04.009
Cite this article as: Yuan Y, Bao HH. Cardiac magnetic resonance imaging in obstructive sleep apnea-hypopnea syndrome patients. Chin J Magn Reson Imaging, 2020, 11(4): 286-290. DOI:10.12015/issn.1674-8034.2020.04.009.

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