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Multimodal MRI findings and misdiagnosis analysis of adult medulloblastoma
OU Yanghong  BAI Yuping  HAN Na  LIU Guangyao  ZHANG Jing 

Cite this article as: Ou YH, Bai YP, Han N, et al. Multimodal MRI findings and misdiagnosis analysis of adult medulloblastoma. Chin J Magn Reson Imaging, 2020, 11(5): 360-363. DOI:10.12015/issn.1674-8034.2020.05.008.


[Abstract] Objective: To discuss multimodal MRI findings of adult medulloblastoma, the understanding of the tumor is deeped and the level of preoperative diagnosis is improved.Materials and Methods: Retrospective analysis of clinical datas and multimodal MRI images of 16 adults medulloblastomas confirmed by pathology.Results: One case was multiple, 1 case was located in the cerebellopontine angle area, 1 case was located in the right frontal and parietal lobes, 7 cases were located in the cerebellar hemisphere, and 6 cases were located in the vermis-four ventricle. One case had bleeding, 8 cases had small blood vessel permeation signs. Tumors have cystic changes. Solid components of tumors showed equal or slightly lower signals on T1WI, T2WI and FLAIR sequences showed equal or slightly higher signals. diffusion weighted imaging (DWI) showed high signal and average ADC value was 0.589×10-3 mm2/s. Five cases were moderately enhanced, 4 cases were significantly enhanced, 1 case showed obvious ring enhancement and 5 cases were patchy or flake-like mildly enhanced. In 7 cases with MR spectroscopy (MRS), the Cho peak was significantly increased, the NAA peak was significantly decreased, and the Cho/NAA value (≥4.8) was significantly increased. Three cases had the diffusion tensor imaging (DTI) examinations. The peritumoral white matter fibers were pushed and some fibers were broken.Conclusions: Multimodal MRI findings in adult medulloblastoma have certain characteristics and are helpful for accurate diagnosis before surgery.
[Keywords] medulloblastoma；brain neoplasms；magnetic resonance imaging；magnetic resonance spectroscopy

OU Yanghong Department of Nuclear Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou 730000, China

BAI Yuping Department of Nuclear Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou 730000, China

HAN Na Department of Nuclear Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou 730000, China

LIU Guangyao Department of Nuclear Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou 730000, China

ZHANG Jing* Department of Nuclear Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou 730000, China

*Corresponding to: Zhang J, E-mail: lztong2001 @163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by the Gansu Youth Science and Technology Fund No. 1606RJYA267 the Scientific Research Project of Colleges and Universities in Gansu Province No. 2018A-124
Received  2019-09-26
Accepted  2020-03-28
DOI: 10.12015/issn.1674-8034.2020.05.008
Cite this article as: Ou YH, Bai YP, Han N, et al. Multimodal MRI findings and misdiagnosis analysis of adult medulloblastoma. Chin J Magn Reson Imaging, 2020, 11(5): 360-363. DOI:10.12015/issn.1674-8034.2020.05.008.

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