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Differential diagnosis value of magnetic resonance diffusion-weighted imaging for suspicious breast cancer
FENG Hao  ZHONG Jianquan  WU Hengping  LIU Yujian  HUANG Yantao  TANG Ling  HUANG Wenjia 

Cite this article as: Feng H, Zhang JQ, Wu HP, et al. Differential diagnosis value of magnetic resonance diffusion-weighted imaging for suspicious breast cancer. Chin J Magn Reson Imaging, 2020, 11(5): 364-366. DOI:10.12015/issn.1674-8034.2020.05.009.


[Abstract] Objective: To investigate the value of ADC, eADC and rADC in breast magnetic resonance diffusion-weighted imaging (DWI), combined with MRI plain scan for the diagnosis and differential value of suspected breast cancer.Materials and Methods: Forty-one patients underwent DWI imaging and were enrolled in the BI-RADS grade IV, and confirmed by surgery and pathology. The ADC value, eADC value and rADC value were measured in the lesion area of interest. The t test was used to compare the two groups. The difference between the good and the malignant was statistically significant at P<0.05. At the same time, according to the size of the ADC value, the distribution of benign and malignant statistics was performed, and the surgical pathological results were used as the gold standard for statistical analysis.Results: In the pairwise comparison, the ADC and rADC values of malignant lesions were lower than those of benign lesions, and the eADC value was higher than that of benign lesions, and the difference was statistically significant (P<0.05);The pathological diagnosis was the gold standard, and the critical value of benign and malignant breast lesions was identified by 1.440×10-3 mm2/s. The sensitivity was 85.7%, the specificity was 55.0%, and the accuracy was 70.7%. The ADC value <1.440×10-3 mm2/s in DWI was used as the criterion for malignancy, Kappa=0.712, which was in good agreement with pathological diagnosis.Conclusions: DWI techniques (ADC values, eADC values, and rADC values) are reliable indicators for identifying differential breast cancer by magnetic resonance imaging; combined with MRI plain scan is more important for the differential diagnosis of benign and malignant BI-RADS classification and grade Ⅳ lesions, and has guiding significance for clinical treatment.
[Keywords] breast neoplasms；magnetic resonance imaging；diagnosis, differential

FENG Hao Department of Radiology, First People's Hospital of Zigong, Sichuan Province, Zigong 643000, China

ZHONG Jianquan* Department of Radiology, First People's Hospital of Zigong, Sichuan Province, Zigong 643000, China

WU Hengping Department of Radiology, First People's Hospital of Zigong, Sichuan Province, Zigong 643000, China

LIU Yujian Department of Radiology, First People's Hospital of Zigong, Sichuan Province, Zigong 643000, China

HUANG Yantao Department of Radiology, First People's Hospital of Zigong, Sichuan Province, Zigong 643000, China

TANG Ling Department of Radiology, First People's Hospital of Zigong, Sichuan Province, Zigong 643000, China

HUANG Wenjia Department of Radiology, First People's Hospital of Zigong, Sichuan Province, Zigong 643000, China

*Corresponding to: Zhong JQ, E-mail: zgyxjys@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  Zigong Health System Research Project No. 2012-7901
Received  2019-01-13
Accepted  2020-03-30
DOI: 10.12015/issn.1674-8034.2020.05.009
Cite this article as: Feng H, Zhang JQ, Wu HP, et al. Differential diagnosis value of magnetic resonance diffusion-weighted imaging for suspicious breast cancer. Chin J Magn Reson Imaging, 2020, 11(5): 364-366. DOI:10.12015/issn.1674-8034.2020.05.009.

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