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The clinical application of magnetic resonance DWI-ADC values in diagnosis of sarcopenia on perimenopausal women
LI Shujin  WU Xiaobing  XIE Ying  LI Xiaoqin  LI Ruirong  YAN Yousong  ZHANG Shaowei 

Cite this article as: Li SJ, Wu XB, Xie Y, et al. The clinical application of magnetic resonance DWI-ADC values in diagnosis of sarcopenia on perimenopausal women. Chin J Magn Reson Imaging, 2020, 11(5): 367-369. DOI:10.12015/issn.1674-8034.2020.05.010.


[Abstract] Objective: To evaluate the diagnostic value of Magnetic resonance DWI-ADC values in diagnosis of sarcopenia on perimenopausal women.Materials and Methods: Women aged 21—30 and 41—60 who accepted MRI in Changˊan Hospital of Dongguan City from Mar 2017 to Nov 2019 was recruited and their data were collected. According of age the included subjects were divided into three groups, namely I group of 21—30 years old, Ⅱ group of 41—50 and Ⅲ group of 51—60. DWI images from the upper margin of the thoracic 12 vertebra to the lower margin of the lumbar 4 vertebra were captured with DWI sequences at Siemens Essenza 1.5 T system. The average ADC values of paravertebral muscles at the level of the lumbar 3 vertebra on the automatically generated ADC maps were measured. SPSS 21.0 was used to perform all analyses. The means of average ADC values were described as (±s). Paired-sample t test was used to compare difference between the means of average ADC values of psoas and erector spinae. Single factor analysis of variance (ANOVA) was used to compare differences on the means of average ADC values of paravertebral muscles among three groups. The difference was statistically significant with P<0.05.Results: Three hundred and sixty-one subjects were included. The means of average ADC values of psoas and erector spinae were respectively 1.279±0.133 and 1.119±0.109, and there was a significant difference between the two groups (t=25.52, P=0.000). The means of average ADC values of paravertebral muscles from I group (n=105), Ⅱ group (n=143) and Ⅲ group (n=113) were respectively 1.220±0.091,1.208±0.084 and 1.159±0.122, and there were significant differences among the three groups (F=11.46, P=0.000). Through further pairwise comparison significant differences were found between I group and Ⅱ group (P<0.01), Ⅱ group and Ⅲ group (P<0.01). Based on 1.038 (-2SD) of average ADC values of paravertebral muscles from I group as diagnostic thresholds of sarcopenia, a total of 23 from Ⅱ group and Ⅲ group were below 1.038. Twenty-two cases among them were confirmed sarcopenia by follow-up.Conclusions: The method of quantifiable DWI-ADC values can reduce the error caused by individual differences in diagnosing sarcopenia and is of great value for qualitative diagnosis of sarcopenia.
[Keywords] sarcopenia；perimenopause；magnetic resonance imaging

LI Shujin* Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

WU Xiaobing Department of Epidemic Prevention, Community Health Services Centre of Chang'an, Guangdong Province, Dongguan 523880, China

XIE Ying Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

LI Xiaoqin Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

LI Ruirong Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

YAN Yousong Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

ZHANG Shaowei Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

*Corresponding to: Li SJ, E-mail: 510615201@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Dongguan Social Science Development (generally) Project No. 2018507150221293
Received  2019-11-07
Accepted  2020-03-28
DOI: 10.12015/issn.1674-8034.2020.05.010
Cite this article as: Li SJ, Wu XB, Xie Y, et al. The clinical application of magnetic resonance DWI-ADC values in diagnosis of sarcopenia on perimenopausal women. Chin J Magn Reson Imaging, 2020, 11(5): 367-369. DOI:10.12015/issn.1674-8034.2020.05.010.

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