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The clinical application of magnetic resonance DWI-ADC values in diagnosis of sarcopenia on perimenopausal women
LI Shujin  WU Xiaobing  XIE Ying  LI Xiaoqin  LI Ruirong  YAN Yousong  ZHANG Shaowei 

Cite this article as: Li SJ, Wu XB, Xie Y, et al. The clinical application of magnetic resonance DWI-ADC values in diagnosis of sarcopenia on perimenopausal women. Chin J Magn Reson Imaging, 2020, 11(5): 367-369. DOI:10.12015/issn.1674-8034.2020.05.010.


[Abstract] Objective: To evaluate the diagnostic value of Magnetic resonance DWI-ADC values in diagnosis of sarcopenia on perimenopausal women.Materials and Methods: Women aged 21—30 and 41—60 who accepted MRI in Changˊan Hospital of Dongguan City from Mar 2017 to Nov 2019 was recruited and their data were collected. According of age the included subjects were divided into three groups, namely I group of 21—30 years old, Ⅱ group of 41—50 and Ⅲ group of 51—60. DWI images from the upper margin of the thoracic 12 vertebra to the lower margin of the lumbar 4 vertebra were captured with DWI sequences at Siemens Essenza 1.5 T system. The average ADC values of paravertebral muscles at the level of the lumbar 3 vertebra on the automatically generated ADC maps were measured. SPSS 21.0 was used to perform all analyses. The means of average ADC values were described as (±s). Paired-sample t test was used to compare difference between the means of average ADC values of psoas and erector spinae. Single factor analysis of variance (ANOVA) was used to compare differences on the means of average ADC values of paravertebral muscles among three groups. The difference was statistically significant with P<0.05.Results: Three hundred and sixty-one subjects were included. The means of average ADC values of psoas and erector spinae were respectively 1.279±0.133 and 1.119±0.109, and there was a significant difference between the two groups (t=25.52, P=0.000). The means of average ADC values of paravertebral muscles from I group (n=105), Ⅱ group (n=143) and Ⅲ group (n=113) were respectively 1.220±0.091,1.208±0.084 and 1.159±0.122, and there were significant differences among the three groups (F=11.46, P=0.000). Through further pairwise comparison significant differences were found between I group and Ⅱ group (P<0.01), Ⅱ group and Ⅲ group (P<0.01). Based on 1.038 (-2SD) of average ADC values of paravertebral muscles from I group as diagnostic thresholds of sarcopenia, a total of 23 from Ⅱ group and Ⅲ group were below 1.038. Twenty-two cases among them were confirmed sarcopenia by follow-up.Conclusions: The method of quantifiable DWI-ADC values can reduce the error caused by individual differences in diagnosing sarcopenia and is of great value for qualitative diagnosis of sarcopenia.
[Keywords] sarcopenia；perimenopause；magnetic resonance imaging

LI Shujin* Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

WU Xiaobing Department of Epidemic Prevention, Community Health Services Centre of Chang'an, Guangdong Province, Dongguan 523880, China

XIE Ying Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

LI Xiaoqin Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

LI Ruirong Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

YAN Yousong Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

ZHANG Shaowei Department of Image Diagnoses, Chang'an Hospital of Dongguan City, Guangdong Province, Dongguan 523843, China

*Corresponding to: Li SJ, E-mail: 510615201@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Dongguan Social Science Development (generally) Project No. 2018507150221293
Received  2019-11-07
Accepted  2020-03-28
DOI: 10.12015/issn.1674-8034.2020.05.010
Cite this article as: Li SJ, Wu XB, Xie Y, et al. The clinical application of magnetic resonance DWI-ADC values in diagnosis of sarcopenia on perimenopausal women. Chin J Magn Reson Imaging, 2020, 11(5): 367-369. DOI:10.12015/issn.1674-8034.2020.05.010.

[1]
Wen X, Wang M, Jiang CM, et al. Are current definitions of sarcopenia applicable for older Chinese adults. J Nutr Health Aging, 2011, 15(13): 847-851.
[2]
Haehling SV, Morley JE, Anker SD. From muscle wasting tosarcopenia and myopenia:update 2012. J Cachexia Sarcopenia Muscle, 2012, 3 (4): 213-217.
[3]
杨尚．上海市杨浦区社区妇女围绝经期综合症的影响因素．苏州：苏州大学, 2015.
[4]
Takahashi K, Takahashi HE, Nakadaira H, et al, Differentchangesof quantity dueto aging inthepsoas major andquadriceps femoris musclesin women. Muscul Skeleton NeuronalInteract, 2006, 6(2): 201-205.
[5]
常建英，黄蓓，蒋铁建,等．绝经后女性肌少症．中国骨质疏松杂志, 2019, 25(9): 1345-1350.
[6]
Bagnall KM, Ford DM, Mefadden KD, et al. The histo-chemical composition of human vertebral muscle. Spine, 1984, 9(5): 470.
[7]
程群，郑丽丽，章振林．肌少症流行病学及发病机制．中华骨质疏松和骨矿盐疾病杂志, 2016, 9(3): 228-235.
[8]
李传夫，李家明．腰大肌损伤性腰腿痛解剖学分析．中国骨伤, 2003, 16(3): 155-156.
[9]
Talbot J, Maves L. Skeletal muscle fiber type: using insights from muscle developmental biology to dissect targets for susceptibility and resistance to muscle disease. Wiley Interdiscip Rev Dev Biol, 2016, 5(4): 518-534.
[10]
Lexell J, Taylor CC, Sjostrom M. What is the cause of aging atrophy. J Neurol Sci, 1988, 84(2-3): 275-294.
[11]
Aloia JF. Mcgowan DM, Vaswani AN, et al. Relationship of menopause to skeletal and muscle mass. Am J Clin Nutr, 1991, 53(6): 1378-1383.
[12]
Rolland YM, Perry HR, Patrick P, et al. Loss of appendicular rmuscle mass and loss of muscle strength in young postmenopausal women. J Gerontol, 2007, 62 (3): 330-335.
[13]
Jubrias SA, Odderson IR, Esselman PC, et al. Decline in isokinetic force with age: muscle cross-sectional area and specific force. Pflugers Arch, 1997, 434(3): 246-253.
[14]
Maltais ML, Desroches J, Dionne IJ. Changes in muscle mass and strength after menopause. J Musculoskelet NeuronalInteract, 2009, 9(4): 186-197.
[15]
于宝海，吴文娟. 2018欧洲肌少症共识解读．河北医科大学学报, 2019, 40(4): 373-379.

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