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• Clinical Article •
Study on diffusion tensor imaging before and after minimally invasive surgery for lumbar disc herniation
HAN Menglong  HE Zhongyun  FANG Xiangjun  TIAN Qiang  HE Weihong  CHEN Xueming 

Cite this article as: Han ML, He ZY, Fang XJ, et al. Study on diffusion tensor imaging before and after minimally invasive surgery for lumbar disc herniation. Chin J Magn Reson Imaging, 2020, 11(6): 422-426. DOI:10.12015/issn.1674-8034.2020.06.005.


[Abstract] Objective: To estimate the application value of diffusion tensor imaging (DTI) technology on detecting the preoperative and postoperative microstructural changes of compressed nerve roots in patients with lumbar disc herniation. And to investigate the DTI obtained data correlation with clinical symptoms.Materials and Methods: 50 patients with unilateral nerve root compression of lumbar disc herniation confirmed by clinical diagnosis and surgery were selected for this study. All patients underwent conventional magnetic resonance imaging sequence, diffusion tensor imaging (DTI) scan, oswestry disability index (ODI) score judgement, and visual analogue scale (VAS) score judgement before surgery and 3 months after surgery. The differences in apparent diffusion coefficient (ADC), fractional anisotropy (FA), ODI score and VAS score were compared. The correlation of DTI parameters with ODI score and with VAS score was analyzed.Results: There was no significant difference in ADC values between the affected nerve roots and the healthy side before surgery (P>0.05). The FA values of the affected nerve roots before surgery were significantly lower than that of the healthy side (P<0.05). The FA values of the affected nerve roots were increased after operation, yet there was no significant difference when it was compared with the healthy side (P>0.05). The preoperative FA value of the affected nerve root was negatively correlated with the preoperative ODI score (r=-0.494, P<0.05) and VAS score (r=-0.560, P<0.05). The FA value of the affected nerve root before surgery was positively correlated with the improvement of ODI score (r=0.492, P<0.05) and VAS score (r=0.435,P<0.05).Conclusions: DTI could be quantitatively used to evaluate the microstructural changes of the compressed nerve roots, and it also provides reference values for the selection of patients' treatments and accurate assessment of postoperative curative effect.
[Keywords] magnetic resonance imaging；diffusion tensor imaging；lumbar disc herniation；nerve root

HAN Menglong# Department of Radiology, the Second Affiliated Hospital, University of South China, Hengyang 421001, China

HE Zhongyun# Department of Radiology, the Affiliated No.331 Hospital of Zhuzhou, Changsha Medical University, Zhuzhou 412002, China

FANG Xiangjun* Department of Radiology, the Second Affiliated Hospital, University of South China, Hengyang 421001, China

TIAN Qiang Department of Radiology, the Affiliated No.331 Hospital of Zhuzhou, Changsha Medical University, Zhuzhou 412002, China

HE Weihong Department of Radiology, the Second Affiliated Hospital, University of South China, Hengyang 421001, China

CHEN Xueming Department of Spinal Surgery, the Affiliated No.331 Hospital of Zhuzhou, Changsha Medical University, Zhuzhou 412002, China

#:Co-first author

*Correspondence to: Fang XJ, E-mail: fangxiangjun118@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Natural Science Foundation of Hunan Province of China No. 2017JJ2235 Guiding Project of Clinical Medical Technology Innovation of Hunan Province No. 2018SK52702 Funding Plan for Key Scientific Research Projects of the Health Talents Project 135 of Zhuzhou No. 2018-26
Received  2020-01-03
Accepted  2020-04-15
DOI: 10.12015/issn.1674-8034.2020.06.005
Cite this article as: Han ML, He ZY, Fang XJ, et al. Study on diffusion tensor imaging before and after minimally invasive surgery for lumbar disc herniation. Chin J Magn Reson Imaging, 2020, 11(6): 422-426. DOI:10.12015/issn.1674-8034.2020.06.005.

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