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• MRI of Uterine Diseases •
The value of DTI and DTT in the depth of myometrial invasion of endometrial cancer stage Ⅰ
CHENG Qichao  WANG Yanming  LI Fei  XIN Jianying  SHEN Zhen  WANG Xizhen  WANG Bin 

Cite this article as: Cheng QC, Wang YM, Li F, et al. The value of DTI and DTT in the depth of myometrial invasion of endometrial cancer stage Ⅰ. Chin J Magn Reson Imaging, 2020, 11(7): 497-500. DOI:10.12015/issn.1674-8034.2020.07.004.


[Abstract] Objective: The study aimed to evaluate endometrial cancer (EC) stage Ⅰ diagnostic value by comparing the diffusion tensor imaging (DTI) parameters and diffusion tensor tractography (DTT) of endometrial cancer stage Ⅰa and Ⅰb, normal myometrium.Materials and Methods: Analyzed the conventional magnetic resonance imaging (MRI) and DTI examination of 40 cases pathologically confirmed endometrial cancer patients and 23 cases normal women. ADW 4.5 station to record the region of interest (ROI) average apparent diffusion coefficient (ADC) value, fractional anisotropy (FA) value, volume ratio anisotropy (VRA) value, and T2-weighted trace (T2-WT) value, and rebuilt DTT. Compared the differences DTI parameters among endometrial cancer stage Ⅰa and Ⅰb, normal myometrium.Results: Endometrial cancer Ⅰa and Ⅰb were 27 and 13 respectively. The ADC value of endometrial cancer stage Ⅰb was lower than stage Ⅰa (t=-3.141, P=0.003), FA valve and VRA valve were higher than stage Ⅰa (t=2.767, 2.947; P=0.009, 0.006), there was no statistically significant of VRA value (P>0.05). Compared with the myometrium, the ADC value was lower (t=-12.141, P=0.000), VRA value and T2-WT value were higher (t=2.523, 8.582; P=0.014, 0.000), there was no statistical difference of FA value between stage Ⅰ endometrial cancer and myometrium (P>0.05). DTT showed that the myometrium fibers of the endometrial cancer were decreased, the arrangement was disordered and irregular and interrupted.Conclusions: DTI parameters and DTT can reflect the microscopic changes to endometrial cancer stage diagnosis, and can be used as an auxiliary diagnosis method in the depth of myometrial invasion.
[Keywords] endometrial neoplasms；magnetic resonance imaging

CHENG Qichao School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

WANG Yanming School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

LI Fei School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

XIN Jianying School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

SHEN Zhen* School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

WANG Xizhen School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

WANG Bin Binzhou Medical University, Institute of Medical Imaging, Yantai 264033, China

*Correspondence to: Shen Z, E-mail: 277132940@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by the Shandong Provincial Natural Science Foundation of China No. ZR2017MH037 Shandong Medical and Health Science and Technology Development Plan No. 2017WS408, 2017WS579 Weifang City Science and Technology Development Plan Project No. 2017YX054
Received  2020-03-21
Accepted  2020-05-20
DOI: 10.12015/issn.1674-8034.2020.07.004
Cite this article as: Cheng QC, Wang YM, Li F, et al. The value of DTI and DTT in the depth of myometrial invasion of endometrial cancer stage Ⅰ. Chin J Magn Reson Imaging, 2020, 11(7): 497-500. DOI:10.12015/issn.1674-8034.2020.07.004.

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