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• MRI of Uterine Diseases •
The value of DTI and DTT in the depth of myometrial invasion of endometrial cancer stage Ⅰ
CHENG Qichao  WANG Yanming  LI Fei  XIN Jianying  SHEN Zhen  WANG Xizhen  WANG Bin 

Cite this article as: Cheng QC, Wang YM, Li F, et al. The value of DTI and DTT in the depth of myometrial invasion of endometrial cancer stage Ⅰ. Chin J Magn Reson Imaging, 2020, 11(7): 497-500. DOI:10.12015/issn.1674-8034.2020.07.004.


[Abstract] Objective: The study aimed to evaluate endometrial cancer (EC) stage Ⅰ diagnostic value by comparing the diffusion tensor imaging (DTI) parameters and diffusion tensor tractography (DTT) of endometrial cancer stage Ⅰa and Ⅰb, normal myometrium.Materials and Methods: Analyzed the conventional magnetic resonance imaging (MRI) and DTI examination of 40 cases pathologically confirmed endometrial cancer patients and 23 cases normal women. ADW 4.5 station to record the region of interest (ROI) average apparent diffusion coefficient (ADC) value, fractional anisotropy (FA) value, volume ratio anisotropy (VRA) value, and T2-weighted trace (T2-WT) value, and rebuilt DTT. Compared the differences DTI parameters among endometrial cancer stage Ⅰa and Ⅰb, normal myometrium.Results: Endometrial cancer Ⅰa and Ⅰb were 27 and 13 respectively. The ADC value of endometrial cancer stage Ⅰb was lower than stage Ⅰa (t=-3.141, P=0.003), FA valve and VRA valve were higher than stage Ⅰa (t=2.767, 2.947; P=0.009, 0.006), there was no statistically significant of VRA value (P>0.05). Compared with the myometrium, the ADC value was lower (t=-12.141, P=0.000), VRA value and T2-WT value were higher (t=2.523, 8.582; P=0.014, 0.000), there was no statistical difference of FA value between stage Ⅰ endometrial cancer and myometrium (P>0.05). DTT showed that the myometrium fibers of the endometrial cancer were decreased, the arrangement was disordered and irregular and interrupted.Conclusions: DTI parameters and DTT can reflect the microscopic changes to endometrial cancer stage diagnosis, and can be used as an auxiliary diagnosis method in the depth of myometrial invasion.
[Keywords] endometrial neoplasms；magnetic resonance imaging

CHENG Qichao School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

WANG Yanming School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

LI Fei School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

XIN Jianying School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

SHEN Zhen* School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

WANG Xizhen School of Medical Imaging, Imaging Center of Affiliated Hospital, Weifang Medical University, Weifang 261053, China

WANG Bin Binzhou Medical University, Institute of Medical Imaging, Yantai 264033, China

*Correspondence to: Shen Z, E-mail: 277132940@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by the Shandong Provincial Natural Science Foundation of China No. ZR2017MH037 Shandong Medical and Health Science and Technology Development Plan No. 2017WS408, 2017WS579 Weifang City Science and Technology Development Plan Project No. 2017YX054
Received  2020-03-21
Accepted  2020-05-20
DOI: 10.12015/issn.1674-8034.2020.07.004
Cite this article as: Cheng QC, Wang YM, Li F, et al. The value of DTI and DTT in the depth of myometrial invasion of endometrial cancer stage Ⅰ. Chin J Magn Reson Imaging, 2020, 11(7): 497-500. DOI:10.12015/issn.1674-8034.2020.07.004.

[1]
高志远，何悦明，柳丽，等．磁共振多序列成像在子宫内膜癌肌层浸润中的诊断价值．放射学实践, 2018, 33(9): 935-939.
[2]
卢婉婷，严思悠，胡志坚，等．子宫内膜癌深肌层浸润相关因素分析及预测．实用妇产科杂志, 2019, 35(6): 459-462.
[3]
尹希，吴慧，高阳，等．不同扩散模型在子宫内膜癌诊断中的应用．磁共振成像, 2018, 9(7): 556-560.
[4]
尹希，吴慧，高阳，等．不同扩散模型对Ⅰ期子宫内膜癌肌层浸润深度的诊断价值．磁共振成像, 2019, 10(4): 258-262.
[5]
Heemskerk AM, Sinha TK, Wilson KJ, et al. Quantitative assessment of DTI-based muscle fiber tracking and optimal tracking parameters. Magn Reson Med, 2009, 61(2): 467-472.
[6]
王锡臻，沈蓁，王滨，等．磁共振扩散张量成像在前列腺疾病诊断中的应用.临床放射学杂志, 2010, 29(7): 926-928.
[7]
韩雨，孙成凤，王习，等．扩散张量成像评价子宫肌瘤高强度聚集超声刀治疗前后的临床价值．实用医学杂志, 2017, 33(15): 2486-2488.
[8]
刘梓菀，吕富荣，肖智博. DTI在子宫及子宫疾病的研究进展．磁共振成像, 2017, 8(11): 876-880.
[9]
吴准，李凤致，王宗英，等. MR扩散张量成像评估子宫腺肌病高强度聚焦超声治疗前后的应用．实用医学杂志, 2019, 35(10): 1652-1654, 1658.
[10]
李翠宁，刘怀军，耿左军，等．右利手年轻人脑结构DTI的T2-weighted trace图定量研究．脑与神经疾病杂志, 2012, 20(4): 268-271.
[11]
Rechichi G, Galimberti S, Signorelli M, et al. Endometrial cancer: correlation of apparent diffusion coefficient with tumor grade, depth of myometrial invasion, and presence of lymph node metastases. AJR Am J Roentgenol, 2011197(1): 256-262.
[12]
孟楠,闫瑞芳，岳巍，等．子宫内膜癌IVIM多模型参数与Ki-67表达水平的相关性分析．临床放射学杂志, 2018, 37(10): 1680-1683.
[13]
刘林枝，范欣，冯宗昊，等. Ki67与子宫内膜癌临床病理特点及预后的关系．中国医刊, 2019, 54(2): 177-183.
[14]
田士峰，刘爱连，刘静红，等．初探基于肿瘤全域ADC图的灰度共生矩阵纹理分析与子宫内膜癌Ki-67表达的相关性．磁共振成像, 2019, 10(11): 826-829.
[15]
Bhosale S, Ingale P, Srivastava S, et al. Diffusion tensor imaging as an additional postoperative prognostic predictor factor in cervical myelopathy patients: an observational study. J Craniovertebr Junction Spine, 2019, 10(1): 10-13.
[16]
门永超，孙成凤，韩雨，等. DTI和DTT评估孕产史对女性盆底肌的影响．实用医学杂志, 2016, 32(20): 3391-3393.
[17]
Holly KS, Fitz-Gerald JS, Barker BJ, et al. Differentiation of high-grade glioma and intracranial metastasis using volumetric. World Neurosurg, 2018, 120: e131-e141.

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