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• MRI of Uterine Diseases •
The value of ESWAN in diagnosis and differential diagnosis of endometrial carcinoma and endometrial polyp
MENG Xing  LIU Ailian  TIAN Shifeng  JU Ye  SONG Qingwei 

Cite this article as: Meng X, Liu AL, Tian SF, et al. The value of ESWAN in diagnosis and differential diagnosis of endometrial carcinoma and endometrial polyp. Chin J Magn Reson Imaging, 2020, 11(7): 501-505. DOI:10.12015/issn.1674-8034.2020.07.005.


[Abstract] Objective: The quantitative parameters of endometrial carcinoma (EC) and endometrial polyp (EP) under enhanced T2* weighted angiography (ESWAN) sequence were analyzed to explore the value of ESWAN in the differential diagnosis of endometrial carcinoma (EC) and endometrial polyp (EP).Materials and Methods: Routine MRI and ESWAN were performed on twenty-five pathologically-diagnosed EC patients and twenty EP patients. ESWAN adopted 5 echoes, with TR of 16.5 ms and TE of 2.1, 5.1, 8.0, 10.9 and 13.8 ms, respectively. Intratumoral susceptibility signal intensity (ITSS) display in the two groups of lesion phase diagrams was scored by two observers, and the Mann-Whitney rank sum test was used to compare the differences in the ITSS display in the two groups of lesion phase. The ESWAN parameters (magnitude value, R2* value and T2* value) were measured by the same two observers in both groups. Intra-class correlation coefficients (ICC) was used to test the consistency of the measurement results of the two observers, independent sample t-test was used to compare the ESWAN parameter values of the two groups of patients, and ROC curve was used to evaluate the diagnostic efficacy of the parameters with statistical difference.Results: The two observers measured data in each group with good consistency (ICC> 0.75). The ITSS scores of EC group and EP group were (1.60±1.29) were higher than that of EP group (0.85±0.99), respectively, and the difference between EC group and EP group was statistically significant (Z=-2.011, P=0.044). The magnitude value, R2* value and T2* value of EC were 817.77±269.65, (16.37±3.65) Hz, (70.56±20.99) ms, respectively. The magnitude value, R2* value and T2* value of EP were 885.43±254.36, (11.62±3.94) Hz, (121.91±54.13) ms, respectively. The R2* value of EC was higher than that of EP, and the T2* value was lower than that of EP, with statistically significant differences (P<0.05). There was no significant difference in magnitude value between the two groups (P>0.05). The AUC of R2* value and T2* value for EC diagnosis were 0.810 and 0.850, respectively, and the threshold were 14.969 and 71.233, respectively.Conclusions: R2* and T2* values are valuable for identifying EC and EP, and EC has more ITSS than EP on the phase map.
[Keywords] endometrial neoplasms；magnetic resonance imaging；quantitative diagnosis；differential diagnosis

MENG Xing Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China; Dalian Municipal Women and Children’s Medical Center, Dalian 116033, China

LIU Ailian* Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

TIAN Shifeng Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

JU Ye Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

SONG Qingwei Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

*Correspondence to: Liu AL, E-mail: liuailian@dmu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS  Program for Training Capital Science and Technology Leading Talents No. Z181100006318003
Received  2020-01-15
Accepted  2020-05-21
DOI: 10.12015/issn.1674-8034.2020.07.005
Cite this article as: Meng X, Liu AL, Tian SF, et al. The value of ESWAN in diagnosis and differential diagnosis of endometrial carcinoma and endometrial polyp. Chin J Magn Reson Imaging, 2020, 11(7): 501-505. DOI:10.12015/issn.1674-8034.2020.07.005.

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