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• Clinical Article •
A research of the resting state network in patients with chronic neck and shoulder pain of cervical spondylosis
WENG Chunjiao  LI Wenjuan  YAO Ziyun  XIE Daohai 

Cite this article as: Wen CJ, Li WJ, Yao ZY, et al. A research of the resting state network in patients with chronic neck and shoulder pain of cervical spondylosis. Chin J Magn Reson Imaging, 2020, 11(7): 511-517. DOI:10.12015/issn.1674-8034.2020.07.007.


[Abstract] Objective: Based on resting-state functional magnetic resonance imaging, independent component analysis (ICA) was used to investigate the functional connectivity changes in the brain network of chronic neck and shoulder pain in cervical spondylosis.Materials and Methods: In our hospital 20 cases of patients with cervical myelopathy (CSM), 30 patients with cervical disc herniation patients (without spinal cord compression) (CDH) and 30 healthy controls (HC) with social recruitment were gathered. Then collected resting-state functional magnetic resonance data and used ICA to extract resting-state brain networks. In addition, analysis of comparison of intra-group network differences among the three groups, and correlation analysis of the different areas and clinical scales.Results: CSM group compared with HC group, the bilateral superior occipital gyrus functional connectivity was enhanced, and the left middle cingulate cortex, left postcentral gyrus, right precentral gyrus and left cerebellum 2 area functional connectivity were reduced. CDH group compared with HC group, the functional connectivity of the right superior frontal gyrus was enhanced, and the functional connectivity of the left middle cingulate cortex, right precentral gyrus, left postcentral gyrus was reduced. Correlation analysis results show, the functional connectivity values of the left postcentral gyrus in CDH was negatively correlated with the visual analogue scale scores (r=-0.535, P=0.002), the functional connectivity values of the left superior occipital gyrus in CSM was negatively correlated with the beck anxiety inventory scores (r=-0.448, P=0.048).Conclusions: There are abnormal functional connectivity in multiple resting-state brain networks in patients with chronic neck and shoulder pain, which are closely related to pain perception, emotional perception, and movement disorders.
[Keywords] chronic neck and shoulder pain；cervical spondylosis；brain network function；resting-state functional magnetic resonance imaging

WENG Chunjiao Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou 215000, China

LI Wenjuan Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou 215000, China

YAO Ziyun Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou 215000, China

XIE Daohai* Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou 215000, China

*Correspondence to: Xie DH, E-mail: sdfyyxhxh@163.com

Conflicts of interest   None.

Received  2020-02-24
Accepted  2020-05-21
DOI: 10.12015/issn.1674-8034.2020.07.007
Cite this article as: Wen CJ, Li WJ, Yao ZY, et al. A research of the resting state network in patients with chronic neck and shoulder pain of cervical spondylosis. Chin J Magn Reson Imaging, 2020, 11(7): 511-517. DOI:10.12015/issn.1674-8034.2020.07.007.

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