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• Clinical Article •
Study on the application of DTI technology in the subtle structural changes of the brain in hypertensive patients with and without obstructive sleep apnea
SUN Zhe  WANG Yunling  JIA Lin  HAN Bingyan  JIA Wenxiao 

Cite this article as: Sun Z, Wang YL, Jia L, et al. Study on the application of DTI technology in the subtle structural changes of the brain in hypertensive patients with and without obstructive sleep apnea. Chin J Magn Reson Imaging, 2020, 11(7): 518-521. DOI:10.12015/issn.1674-8034.2020.07.008.


[Abstract] Objective: Using diffusion tensor imaging (DTI) to investigate the subtle structural changes in the hypothalamus of patients with and without hypertension and sleep disorders.Materials and Methods: Twenty patients with hypertension and sleep disorder from the Second Affiliated Hospital of Xinjiang Medical University were selected as the case group. Twenty patients with hypertension without sleep disturbance were taken as the control group, using DTI technology score of two groups of patients with hypothalamic fractional anisotropy (FA) and apparent diffusion coefficient (ADC) value. Statistical methods were used to retrospectively compare the differences of FA and ADC values between the two groups, and evaluate the correlation between the two groups of FA value, ADC values.Results: FA=0.31±0.11 in the case group, FA=0.50±0.12 in the control group, P=0.00. The FA value in the case group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). ADC in the case group was 1.84±0.73, ADC in the control group was 1.45±0.41, P=0.045. ADC value in the case group was higher than that in the control group, with statistically significant difference (P<0.05). At the same time, it was found that the analysis results of the correlation between the duration of hypertension and the score of sleep disorders showed that r=0.836, P<0.001, indicating that there was a significant positive correlation between the duration of hypertension and the score of sleep disorders (P <0.05).Conclusions: DTI technology can be found that there are subtle structural changes in the hypothalamus in patients with and without hypertension and sleep disorders.
[Keywords] hypertension；sleep disorders；magnetic resonance imaging

SUN Zhe Imaging Center of the Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

WANG Yunling Imaging Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi 83000, China

JIA Lin Imaging Center of the First Affiliated Hospital of Xinjiang Medical University, Urumqi 83000, China

HAN Bingyan Imaging Center of the Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

JIA Wenxiao* Xinjiang Medical University, Urumqi 8830000, China

*Correspondence to: Jia WX, E-mail: JWXXJ@sina.com

Conflicts of interest   None.

Received  2020-02-07
Accepted  2020-05-21
DOI: 10.12015/issn.1674-8034.2020.07.008
Cite this article as: Sun Z, Wang YL, Jia L, et al. Study on the application of DTI technology in the subtle structural changes of the brain in hypertensive patients with and without obstructive sleep apnea. Chin J Magn Reson Imaging, 2020, 11(7): 518-521. DOI:10.12015/issn.1674-8034.2020.07.008.

[1]
Palagini L, Bruno RM, Cheng P, et al. Relationship between insomnia symptoms, perceived stress and coping strategies in subjects with arterial hypertension: psychological factors may play a modulating role. Sleep Medicine, 2016, 19(5): 108-115.
[2]
刘冰，李华，毕鸿雁．高血压与睡眠障碍相关研究进展．中国老年保健医学, 2017, (3): 55-57.
[3]
朱令圆，龙荪瀚，吴玉攀，等．我国中老年人睡眠时间与高血压的关联性研究．中国慢性病防治与控制, 2019, (6): 421-424.
[4]
Pagonabarraga J, Kulisevsky J. Cognitive impairment and dementia in Parkinson’s disease. Neurobiol Dis, 2012, 46, (3): 590-596.
[5]
Sorg SF, Delano-Wood L, Luc N, et al. White matter integrity in veterans with mild traumatic brain injury: associations with executive function and loss of consciousness. J Head Trauma Rehabil, 2014, 29(2): 446-452.
[6]
古丽妮嗄尔·菲达，贾琳，贾文霄. DTI定量参数对前列腺癌病理分级的诊断价值．新疆医科大学学报, 2018, 41(5): 552-556.
[7]
贝天霞，程敬亮，白洁，等. ADC值鉴别诊断脑实质室管膜瘤与胶质母细胞瘤．中国医学影像技术, 2019, 35(1): 421-424.
[8]
刘力生．中国高血压防治指南2010.中华高血压杂志, 2011, 19(8): 701-743.
[9]
Buysse DJ, Rcynolds CF 3rd, Monk TH, et al. The Pittsburgh Sleep Quality Index:a new instrument for psychiatric practice and research. Psychiatry Res, 1989, 28(2): 103-107.
[10]
Knutson KL, Van Cauter E, Rathouz PJ, et al. Association between sleep and blood pressure in midlife: the CARDIA sleep study. Archiv Inter Med, 2009, 169(11): 1055-1061.
[11]
Gottlieb DJ, Redline S, Nieto FJ, et al. Association of usual sleep duration with hypertension: the sleep heart health study. Sleep, 2006, 29(7): 1009-1014.
[12]
Mccubbin JA, Pilcher JJ, Moore DD. Blood pressure increases during a simulated night shift in persons at risk for hypertension. Inter J Behav Med, 2010, 17(12): 314-320.
[13]
Liu RQ, Qian Z, Trevathan E, et al. Poor sleep quality associated with high risk of hypertension and elevated blood pressure in China: results from a large population-based study. Hypertens Res, 2016, 39(1): 54-59.
[14]
董双君，王云玲，王红，等．扩散张量成像评价颈总动脉交感神经网剥脱术治疗儿童脑瘫的价值．磁共振成像, 2018, 9(1): 43-47.
[15]
黄文胜，周红．磁共振张量成像技术在脑白质病变与认知功能障碍关系研究中的作用．东南大学学报, 2013, 32(4): 522-525.
[16]
王博，王忠，张瑞剑，等．磁共振弥散张量成像技术在神经外科疾病的应用进展．临床外科神经杂志, 2020, 21(1): 116-120.
[17]
陈珊红，张杨贵，谭学渊，等．扩散张量成像(DTI)技术在脑部恶性肿瘤中的应用价值．中国CT和MRI杂志, 2018, 16(11): 11-14.
[18]
陈慧恩，孙井松，菜厚洪，等. DTI成像技术在脊髓震荡损伤中的应用价值．中国CT和MRI杂志, 2016, 14(10): 30-32, 54.
[19]
王勇，张晖，耿左军，等．高场强磁共振扩散张量成像对单纯脑白质疏松症及多发性硬化的鉴别诊断价值．医学综述, 2015, 9(21): 3203-3206.

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