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Clinical Article
The value of ADC value in T staging and histologic differentiation grade of esophageal cancer
SUN Jing  WANG Zhu 

Cite this article as: Sun J, Wang Z. The value of ADC value in T staging and histologic differentiation grade of esophageal cancer. Chin J Magn Reson Imaging, 2020, 11(7): 531-534. DOI:10.12015/issn.1674-8034.2020.07.011.


[Abstract] Objective: To analyze the correlation with T stage, histologic differentiation grade of esophageal cancer.Materials and Methods: A total of 45 pathologically confirmed patients with esophageal cancer were included. Mean tumor apparent diffusion coefficient (ADC) for different histologic differentiation grades, T-stages were measured and compared.Results: The average ADC value of esophageal cancer was negatively correlated with the T staging, and the ADC value decreased with the increase of T staging. The results of Spearson correlation analysis showed that average ADC value was negatively correlated with T stage (r=-0.645, P<0.01). The average ADC value of the low-differentiation group was lower than that of the medium-high differentiation group (1.8514±0.40295)×10-3 mm2/s, 1.7125±0.37767)×10-3 mm2/s). There were no significant differences in ADC value no matter what kind of histological grade.Conclusions: DWI was useful for evaluating T stage of esophageal cancer, and can reflect the clinical T stage of esophageal cancer, providing help for clinical treatment.
[Keywords] esophageal neoplasms;magnetic resonance imaging;diffusion magnetic resonance imaging

SUN Jing Department of Diagnostic, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

WANG Zhu* Department of Diagnostic, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

*Correspondence to: Wang Z, E-mail: wangzhu@cicams.ac.cn

Conflicts of interest   None.

Received  2019-12-15
Accepted  2020-05-21
DOI: 10.12015/issn.1674-8034.2020.07.011
Cite this article as: Sun J, Wang Z. The value of ADC value in T staging and histologic differentiation grade of esophageal cancer. Chin J Magn Reson Imaging, 2020, 11(7): 531-534. DOI:10.12015/issn.1674-8034.2020.07.011.

[1]
Zhang X, Wang Y, Jiang Y, et al. The prognostic impact of tumor length in esophageal cancer: protocol for a systematic review and meta-analysis. Medicine, 2018, 97(43): e12902.
[2]
Hou X, Wei JC, Fu JH, et al. Proposed modification of the seventh American joint committee on cancer staging system for esophageal squamous cell carcinoma in chinese patients. Ann Surg Oncol, 2014, 21(1): 337-342.
[3]
Ruol A, Castoro C, Portale G, et al. Trends in management and prognosis for esophageal cancer surgery: twenty-five years of experience at a single institution. Arch Surg, 2009, 144(3): 247-254.
[4]
Xie T, Xiang R, Yang X, et al. Analysis of characteristics and factors affecting the recurrence of esophageal cancer within the first year after surgery. Zhonghua Zhongliu Zazhi, 2016, 38(2): 146-149.
[5]
Algebally AM, Mohey N, Szmigielski W, et al. The value of high-resolution mri technique in patients with rectal carcinoma: pre-operative assessment of mesorectal fascia involvement, circumferential resection margin and local staging. Pol J Radiol, 2015, 80: 115-121.
[6]
Giovagnoni A, Valeri G, Ferrara C. MRI of esophageal cancer. Abdom Radiol, 2002, 27(4): 361.
[7]
Curvo-Semedo, Lambregts DM, Maas M, et al. Diffusion-weighted MRI in rectal cancer: apparent diffusion coefficient as a potential noninvasive marker of tumor aggressiveness. J Magn Reson Imaging, 2012, 35(6): 1365-1371.
[8]
Desouza N, Riches S, Vanas N, et al. Diffusion-weighted magnetic resonance imaging: a potential non-invasive marker of tumour aggressiveness in localized prostate cancer. Clin Radiol, 2008, 63(7): 774-782.
[9]
Nakashima A, Nakashima K, Seto H, et al. Thoracic esophageal carcinoma: Evaluation in the sagittal section with magnetic resonance imaging. Abdom Imaging, 1997, 22(1): 20-23.
[10]
Van Rossum P, Van Lier A, Lips I, et al. Imaging of oesophageal cancer with fdg-pet/CT and MRI. Clin Radiol, 2015, 70(1): 81-95.
[11]
Baliyan V, Das CJ, Sharma R, et al. Diffusion weighted imaging: Technique and applications. World J Radiol, 2016, 8(9): 785.
[12]
White NS, McDonald CR, Farid N, et al. Diffusion-weighted imaging in cancer: Physical foundations and applications of restriction spectrum imaging. Cancer Res, 2014, 74(17): 4638-4652.
[13]
Steiger P, Barbieri S, Kruse A, et al. Selection for biopsy of kidney transplant patients by diffusion-weighted mri. Eur Radiol, 2017, 27(10): 4336-4344.
[14]
Yoshida S, Kobayashi S, Koga F, et al. 240 the ADC value is a prognostic biomarker of upper urinary tract cancer: potential application to preoperative risk stratification. Eur Urol Supplements, 2013, 12(1): e240-e241.
[15]
Chinese guidelines for diagnosis and treatment of esophageal carcinoma 2018 (English version). Chin J Cancer Res, 2019, 31(2): 223.
[16]
Iima M, Le Bihan D. Clinical intravoxel incoherent motion and diffusion MR imaging: Past, present, and future. Radiology, 2016, 278(1): 13-32.
[17]
Huang YC, Chen TW, Zhang XM, et al. Intravoxel incoherent motion diffusion-weighted imaging of resectable oesophageal squamous cell carcinoma: association with tumour stage. Br J Radiol, 2018, 91(1084): 20170421.
[18]
Zhu S, Wei Y, Gao F, et al. Esophageal carcinoma: Intravoxel incoherent motion diffusion-weighted MRI parameters and histopathological correlations. J Magn Reson Imaging, 2019, 49(1): 253-261.
[19]
Cong Q, Li G, Wang Y, et al. DW-MRI for esophageal squamous cell carcinoma, correlations between ADC values with histologic differentiation and vegf expression: a retrospective study. Oncol letter, 2019, 17(3): 2770-2776.
[20]
Togao O, Hiwatashi A, Yamashita K, et al. Differentiation of high-grade and low-grade diffuse gliomas by intravoxel incoherent motion MR imaging. Neuro Oncol, 2015, 18(1): 132-141.
[21]
Bhamidipati CM, Stukenborg GJ, Thomas CJ, et al. Pathologic lymph node ratio is a predictor of survival in esophageal cancer. Ann Thorac Surgery, 2012, 94(5): 1643-1651.

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