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• Clinical Guidelines & Expert Consensus •
Imaging diagnosis criteria of acquired immunodeficiency syndrome associated PCNSL
Imaging Committee on Infections, Chinese Society of Radiology
Committee on Infectious Disease, Radiology Committee, Chinese Medical Doctor Association;
Radiology of Infection and Inflammation Chinese Research Hospital Association;
Imaging Committee on InfectionsChinese Association of STD&AIDS Prevention;
Imaging Group on Infections, Avocation of Infections Disease Hospital
Beijing Medical Imaging Technology Innovation Alliance

Cite this article as: Imaging Committee on Infections, Chinese Society of Radiology; Committee on Infectious Disease, Radiology Committee, Chinese Medical Doctor Association; Radiology of Infection and Inflammation, Chinese Research Hospital Association; et al. Imaging diagnosis criteria of acquired immunodeficiency syndrome associated PCNSL. Chin J Magn Reson Imaging, 2020, 11(8): 601-606. DOI:10.12015/issn.1674-8034.2020.08.001.


[Abstract] Acquired immune deficiency syndrome (AIDS) related primary central nervous system lymphoma (PCNSL) has unique imaging manifestations. Based on the summary of literature case statistics and the latest research evidence, we formed the updated imaging diagnostic recommendation: MRI without and with contrast scanning is the strongly recommended examination methods for AIDS-related PCNSL. Imaging signs or findings summarized as follows: THREE HIGH, increased diffusion weighted imaging (DWI) signal in solid parts of the tumor, high density of CT without contrast, and basically uniform enhancement. TWO LOW, hypo-intensity of ADC maps, iso-or hypo-intensity of T1WI without contrast and T2WI. THREE COMMON, mostly located in the midline structural area of the brain, often manifested as multiple, cystic changes. The special MRI enhancement was characterized by "Notch sign" "Sharp Angle sign" "Snow-holding sign" and "Jagged or Spinous shape". For clinical suspected cases, such as imaging examination in accordance with the above findings, can be used as the imaging diagnostic criteria of AIDS related PCNSL, so as to provide a rich, accurate diagnostic information for clinical with a definite diagnosis, effectively to improve the ability of AIDS related PCNSL early diagnosis, in order to easily form the optimal decision scheme, and to achieve truly early and precise treatment.
[Keywords] AIDS-related；brain lymphoma；primary central nervous system lymphom；magnetic resonance imaging

Imaging Committee on Infections, Chinese Society of Radiology   Committee on Infectious Disease, Radiology Committee, Chinese Medical Doctor Association;   Radiology of Infection and Inflammation Chinese Research Hospital Association;   Imaging Committee on InfectionsChinese Association of STD&AIDS Prevention;   Imaging Group on Infections, Avocation of Infections Disease Hospital   Beijing Medical Imaging Technology Innovation Alliance  

*Corresponding to: Li HJ, E-mail: lihongjun00113@126.com Liu HQ, E-mail: drhancher@163.com

Conflicts of interest   None.

Received  2020-04-10
Accepted  2020-06-12
DOI: 10.12015/issn.1674-8034.2020.08.001
Cite this article as: Imaging Committee on Infections, Chinese Society of Radiology; Committee on Infectious Disease, Radiology Committee, Chinese Medical Doctor Association; Radiology of Infection and Inflammation, Chinese Research Hospital Association; et al. Imaging diagnosis criteria of acquired immunodeficiency syndrome associated PCNSL. Chin J Magn Reson Imaging, 2020, 11(8): 601-606. DOI:10.12015/issn.1674-8034.2020.08.001.

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