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• Clinical Guidelines & Expert Consensus •
The basis and application of parameters derived from MR as endpoints of myocardial infarction—the interpretation of a consensus statement for cardiac MR endpoints selection in myocardial infarction trials
YANG Shujuan  ZHAO Shihua 

Cite this article as: Yang SJ, Zhao SH. The basis and application of parameters derived from MR as endpoints of myocardial infarction—The interpretation of a consensus statement for cardiac MR endpoints selection in myocardial infarction trials. Chin J Magn Reson Imaging, 2020, 11(8): 607-609. DOI:10.12015/issn.1674-8034.2020.08.002.


[Abstract] With the update of the research evidence related to myocardial infarction (MI), the parameters of cardiovascular magnetic resonance (CMR) has become surrogate endpoints with proven links to hard outcomes. An expert consensus statement for CMR endpoints selection in MI experimental and clinical trials was released by the American College of Cardiology Foundation (ACCF) in 2019. The consensus, based on a large amount of evidence and cutting-edge research, summarizes the pathophysiology of myocardial ischemia/reperfusion injury and CMR tissue characterization of MI, as well as the CMR endpoints selection for studies related to MI is recommended. The author interprets the update viewpoints in this consensus in order to provide a reference for the direction of experimental and clinical research about MI and CMR in the future.
[Keywords] cardiac magnetic resonance；myocardial infarction；endpoint；clinical trial；experimental trial

YANG Shujuan MR Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases of China, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China

ZHAO Shihua* MR Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases of China, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China

*Corresponding to: Zhao SH, E-mail: cjrzhaoshihua2009@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of the Key Projects of National Natural Science Foundation of China No. 81930044, 81620108015
Received  2020-05-11
Accepted  2020-06-23
DOI: 10.12015/issn.1674-8034.2020.08.002
Cite this article as: Yang SJ, Zhao SH. The basis and application of parameters derived from MR as endpoints of myocardial infarction—The interpretation of a consensus statement for cardiac MR endpoints selection in myocardial infarction trials. Chin J Magn Reson Imaging, 2020, 11(8): 607-609. DOI:10.12015/issn.1674-8034.2020.08.002.

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