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Clinical characteristics and imaging features of primary hepatic neuroendocrine neoplasm
SHI Dongli  MA Liang  LI Hongjun 

Cite this article as: Shi DL, Ma L, Li HJ. Clinical characteristics and imaging features of primary hepatic neuroendocrine neoplasm. Chin J Magn Reson Imaging, 2020, 11(8): 655-658. DOI:10.12015/issn.1674-8034.2020.08.012.


[Abstract] Objective: To investigate the clinical characteristics and imaging features of primary hepatic neuroendocrine neoplasms (PHNENs).Materials and Methods: Clinical pathological information and imaging features of 11 histopathologically confirmed PHNEN patients were retrospectively reviewed.Results: All the patients were negative for liver hepatitis cirrhosis except one. The positive rate for neuron-specific enolase (NSE) was 75%. The histopathologic classifications of the 11 cases were NET (n=6; G1=1, G2=5) and NEC (n=5). The PHNENs can be single lesion (NET=4; NEC=1) or multiple lesions (NET=2; NEC=4). Seven cases (NET=3; NEC=4) were heterogeneous for the cystic change (n=4), hemorrhage (n=2) and calcification (n=1). Two patients had fluid-fluid levels. The lesions were restricted on MR diffusion weighted image (DWI) (n=6). Nine cases showed strong global enhancement and 8 cases exhibited wash out including 4 patients with hepatobiliary phase images showing hypointensity. Tumors on digital subtraction angiography (DSA) were manifested as hypervascular mass.Conclusions: PHNENs has specific features on clinics and imaging findings and they are valuable in the diagnosis and differential diagnosis.
[Keywords] neuroendocrine neoplasms；liver neoplasms；computed tomography；magnetic resonance imaging

SHI Dongli Department of Diagnostic Radiology, Affiliated Youan Hospital of Capital Medical University, Beijing 100069, China

MA Liang Centre of Interventional Oncology and Liver Disease, Affiliated Youan Hospital of Capital Medical University, Beijing 100069, China

LI Hongjun* Department of Diagnostic Radiology, Affiliated Youan Hospital of Capital Medical University, Beijing 100069, China

*Corresponding to: Li HJ, E-mail: lihongjun00113@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Key Projects of National Natural Science Foundation of China No.61936013
Received  2020-05-06
Accepted  2020-06-18
DOI: 10.12015/issn.1674-8034.2020.08.012
Cite this article as: Shi DL, Ma L, Li HJ. Clinical characteristics and imaging features of primary hepatic neuroendocrine neoplasm. Chin J Magn Reson Imaging, 2020, 11(8): 655-658. DOI:10.12015/issn.1674-8034.2020.08.012.

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