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Value of magnetic resonance imaging combined with peripheral blood human leukocyte antigen B27 detection in evaluating hip joint lesions in ankylosing spondylitis patients
ZENG Ling  CHEN Xi  LIANG Chuan  FANG Jinzhi 

Cite this article as: Zeng L, Chen X, Liang C, et al. Value of magnetic resonance imaging combined with peripheral blood human leukocyte antigen B27 detection in evaluating hip joint lesions in ankylosing spondylitis patients. Chin J Magn Reson Imaging, 2020, 11(8): 666-668. DOI:10.12015/issn.1674-8034.2020.08.015.


[Abstract] Objective: To investigate the value of magnetic resonance imaging combined with peripheral blood human leukocyte antigen B27 (HLA-B27) detection in evaluating hip joint lesions in ankylosing spondylitis (AS) patients.Materials and Methods: One hundred and eighty-six AS patients with hip joint lesions treated in our hospital from February 2017 to February 2019 were enrolled, all patients received the magnetic resonance imaging and HLA-B27 detection. The accuracy of different examinations was compared, and the diagnostic value of the two methods for AS patients with hip joint disease was also analyzed.Results: The examination showed that 152 cases of HLA-B27 were positive in peripheral blood and 34 cases were negative, with a positive rate of 81.72%; The results of MRI showed that 280 hips (83.33%) were involved in 186 AS patients, 210 hips (75.00%) had hydrocele and 181 hips (64.64%) had bone marrow edema.Other types of AS hip joint lesions accounted for less than 60%.The detection rate of MRI + HLA-B27 examination was significantly higher than that of MRI examination (96.43% vs 83.33%, P<0.05).Conclusions: MRI combined with peripheral blood HLA-B27 detection can effectively improve the diagnostic accuracy of AS patients with hip joint disease.
[Keywords] ankylosing spondylitis；hip joint disease；magnetic resonance imaging；human leukocyte antigen B27 in peripheral blood

ZENG Ling Department of Medical Imaging, Longhua District People's Hospital, Shenzhen 518109, China

CHEN Xi Department of Medical Imaging, Longhua District People's Hospital, Shenzhen 518109, China

LIANG Chuan Department of Medical Imaging, Longhua District People's Hospital, Shenzhen 518109, China

FANG Jinzhi* Department of Medical Imaging, Longhua District People's Hospital, Shenzhen 518109, China

*Corresponding to: Fang JZ, E-mail:czzxfjz@163.com

Conflicts of interest   None.

Received  2019-10-09
Accepted  2020-04-13
DOI: 10.12015/issn.1674-8034.2020.08.015
Cite this article as: Zeng L, Chen X, Liang C, et al. Value of magnetic resonance imaging combined with peripheral blood human leukocyte antigen B27 detection in evaluating hip joint lesions in ankylosing spondylitis patients. Chin J Magn Reson Imaging, 2020, 11(8): 666-668. DOI:10.12015/issn.1674-8034.2020.08.015.

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