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The principle of amide proton transfer imaging and advances in arterial occlusive cerebral infarction
JIANG Yuhan  MIAO Yanwei  CHANG Peipei  CHE Yiwei 

Cite this article as: Jiang YH, Miao YW, Chang PP, et al. The principle of amide proton transfer imaging and advances in arterial occlusive cerebral infarction. Chin J Magn Reson Imaging, 2020, 11(10): 928-930, 946. DOI:10.12015/issn.1674-8034.2020.10.023.


[Abstract] Cerebral infarction is the most common cerebrovascular disease, and arterial occlusive infarction is the common type. Decreased blood perfusion in the cerebral arterial blood supply area causes a series of pathophysiological changes, including changes in metabolism and chemical environment. Currently, computed tomography (CT) or MRI structural images, and even some conventional functional imaging, are difficult to show acid-base metabolic changes in cerebral infarction. Amide proton transfer (APT) imaging technique can detect the changes of brain metabolites, evaluate the metabolic changes of brain tissue after infarction, and clarify the chemical environment evolution of ischemic tissue. In this paper, we reviewed the progress in arterial occlusive cerebral infarction with amide proton transfer imaging.
[Keywords] cerebral infarction；amide proton transfer imaging；magnetic resonance imaging；metabolism

JIANG Yuhan Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

MIAO Yanwei* Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

CHANG Peipei Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

CHE Yiwei Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

*Correspondence to: Miao YW, E-mail: ywmiao716@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 81671646
Received  2020-04-24
Accepted  2020-06-12
DOI: 10.12015/issn.1674-8034.2020.10.023
Cite this article as: Jiang YH, Miao YW, Chang PP, et al. The principle of amide proton transfer imaging and advances in arterial occlusive cerebral infarction. Chin J Magn Reson Imaging, 2020, 11(10): 928-930, 946. DOI:10.12015/issn.1674-8034.2020.10.023.

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