A preliminary study on the central analgesic mechanism of acupuncturing the stomach meridian foot-Yangming by fMRI

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• Clinical Article •

BIAN Wenjin ZHEN Junping JIN Bo ZHOU Yukun YANG Jie FAN Zhichang

Cite this article as: Bian WJ, Zhen JP, Jin B, et al. A preliminary study on the central analgesic mechanism of acupuncturing the stomach meridian foot-Yangming by fMRI. Chin J Magn Reson Imaging, 2020, 11(11): 979-984. DOI:10.12015/issn.1674-8034.2020.11.005.

Abstract

[Abstract] Objective: To explore the central analgesic mechanism of acupuncture of the stomach meridian of foot-Yangming by comparing and analysing the changes of brain functional imaging after pain stimulation and acupuncture point analgesia.Materials and Methods: Twenty healthy volunteers were given pain stimulation and acupuncture at Zusanli and Shangjuxu points in stomach meridian of foot-Yangming respectively. The actived and inhibited area in the brain was recorded by fMRI and analyzed.Results: After pain stimulation and compatibility of acupuncture at two points, the frontal and temporal cortex, the limbic system, the thalamus,the cerebellum and so on are activated and inhibited in varying degrees and ranges in brain functional imaging, and the difference is statistically significant (k>30, t>3.09, P<0.001).Conclusions: These brain areas reflected by brain functional imaging may participate in pain and the central analgesic mechanism of stomach meridian of foot-Yangming through different regulation ways. And there are both similarities and differences between the central analgesic mechanism of stomach meridian of foot-Yangming and single acupuncture point.

[Keywords] acupuncture；pain；analgesic mechanism；functional magnetic resonance imaging of brain；stomach meridian of foot-Yangming

Contributor Information

BIAN Wenjin Shanxi Medical University, Taiyuan 030001, China

ZHEN Junping^* Department of Imaging, the Second Hospital of Shanxi Medical University, Taiyuan 030001, China

JIN Bo Shanxi Medical University, Taiyuan 030001, China

ZHOU Yukun Shanxi Medical University, Taiyuan 030001, China

YANG Jie Shanxi Medical University, Taiyuan 030001, China

FAN Zhichang Shanxi Medical University, Taiyuan 030001, China

*Correspondence to: Zhen JP, E-mail: harrygin@163.com

Conflicts of interest None.

Publication Information

ACKNOWLEDGMENTS This article is supported by the Shanxi Returned Overseas Students Research Funding Project No. 2014-077

Received 2020-03-13

Accepted 2020-09-18

DOI: 10.12015/issn.1674-8034.2020.11.005

Text

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