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Current status of spinal cord MRI study of amyotrophic lateral sclerosis
WANG Juan  ZHENG Senyuan  HUANG Pan 

Cite this article as: Wang J, Zheng SY, Huang P. Current status of spinal cord MRI study of amyotrophic lateral sclerosis. Chin J Magn Reson Imaging, 2020, 11(11): 1048-1050. DOI:10.12015/issn.1674-8034.2020.11.021.


[Abstract] Amyotrophic lateral sclerosis (ALS) is the most common type of motor neuron disease (MND), showing continuous worsen. There is currently no effective treatment. Nursing and respiratory support have significantly improved the patient's quality of life and survival rate. However, due to the heterogeneity of clinical manifestations, the average time from symptom onset to diagnosis is long. In view of this, finding new biomarkers to assist diagnosis and prognosis assessment becomes particularly important. Magnetic resonance imaging is safe, noninvasive, and easy to collect, and is a reasonable choice as a biomarker. The vast majority of current ALS imaging studies focus on cerebral changes, which are limited to upper motor neurons. Spinal cord MRI can study both upper motor neurons and lower motor neurons at the same time, so it may be a sensitive marker for early disease.
[Keywords] amyotrophic lateral sclerosis；spinal cord；magnetic resonance imaging

WANG Juan Department of Neurology, Deyang People's Hospital of Sichuan Province, Deyang 618000, China

ZHENG Senyuan Department of Neurology, Deyang People's Hospital of Sichuan Province, Deyang 618000, China

HUANG Pan* Department of Neurology, Deyang People's Hospital of Sichuan Province, Deyang 618000, China

*Correspondence to: Huang P, E-mail: 1032857970@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  The Science and Technology Project of Health Planning Committee of Sichuan No. 20PJ239
Received  2020-06-02
Accepted  2020-09-28
DOI: 10.12015/issn.1674-8034.2020.11.021
Cite this article as: Wang J, Zheng SY, Huang P. Current status of spinal cord MRI study of amyotrophic lateral sclerosis. Chin J Magn Reson Imaging, 2020, 11(11): 1048-1050. DOI:10.12015/issn.1674-8034.2020.11.021.

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