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• Clinical Article •
MRI features of the submandibular gland in Sjögren syndrome
JI Quanshu  DING Changwei  WANG Yue 

Cite this article as: Ji QS, Ding CW, Wang Y. MRI features of the submandibular gland in Sjögren syndrome. Chin J Magn Reson Imaging, 2020, 11(12): 1129-1132. DOI:10.12015/issn.1674-8034.2020.12.010.


[Abstract] Objective: To investigate the MRI imaging features and diagnostic efficacy of submandibular glands in patients with Sjögren's syndrome (SS).Materials and Methods: MRI images of the submandibular glands of 31 patients diagnosed with SS and 15 healthy volunteers were collected. Observed T1WI, T2WI and lipid-suppressing T2WI images, and classified the fat signal of the submandibular glands of the patients. Measured the volume of the bilateral submandibular glands of the subject and observed the volume changes of the two groups.Results: All patients showed uneven changes in bilateral submandibular gland signals. Both T1WI and T2WI images showed multiple diffuse fat signals, and lipid-suppressed T2WI showed low signals. Of the 62 glands, 50 lesions were detected by conventional MRI, with no false positive results. There are 12 at grade 0, 14 at grade 1, 10 at grade 2, 13 at grade 3, and 13 at grade 4. There were no fat signals in 30 submandibular glands in 15 cases in the control group, and the fat signal grade was 0. The sensitivity of the submandibular gland was 80.7%, and the positive predictive value was 100%, specificity is 100%. The AUC of submandibular gland fat signal classification is 0.903. The volume of the submandibular gland in the case group was less than that of the control group (P<0.05), and the volume of the non-grade submandibular gland in the case group was less than that of grade 0 (P<0.05). The correlation between the volume of submandibular glands and the classification of fat signals in the case group was poor (r=-0.102, P>0.05), and the results were not statistically significant.Conclusions: Routine submandibular gland MRI examination can be used as one of the imaging examinations to diagnose SS.
[Keywords] Sjögren’s syndrome；submandibular gland；magnetic resonance imaging

JI Quanshu Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China

DING Changwei* Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China

WANG Yue Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China

*Correspondence to: Ding CW, E-mail: 18940254003@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Natural Science Foundation Project of Liaoning Province No.20170541045
Received  2020-06-22
Accepted  2020-08-04
DOI: 10.12015/issn.1674-8034.2020.12.010
Cite this article as: Ji QS, Ding CW, Wang Y. MRI features of the submandibular gland in Sjögren syndrome. Chin J Magn Reson Imaging, 2020, 11(12): 1129-1132. DOI:10.12015/issn.1674-8034.2020.12.010.

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