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Magnetic resonance imaging findings of jaw in 9 patients with SAPHO syndrome
YU Meiyan  ZHANG Ya’nan  REN Mengmeng  HONG Yueying  LI Junqiu  LI Chen  LU Xinyu  ZHANG Wen  HUO Jianwei 

Cite this article as: Yu MY, Zhang YN, Ren MM, et al. Magnetic resonance imaging findings of jaw in 9 patients with SAPHO syndrome. Chin J Magn Reson Imaging, 2020, 11(12): 1148-1151. DOI:10.12015/issn.1674-8034.2020.12.014.


[Abstract] Objective: To investigate magnetic resonance imaging findings of jaw in patients with SAPHO syndrome and to improve our understanding of the disease.Materials and Methods: The MRI data of 9 patients with SAPHO in our department were reviewed. Two experienced radiologists read the films together, to assess the extent and degree of the bone marrow edema, hyperostosis, hypertrophy and fat infiltration of the mandible, the involvement of mandibular joints and surrounding tissues, and the diffusion limitation of lesions revealed by diffusion weighted imaging. The discrepancies were reached in consensus after discussion.Results: All the 9 patients of mandible with SAPHO exhibited varying degrees of abnormalities on magnetic resonance imaging. All of the patients show the marrow edema, mainly involving the body of the mandible, of which 8 cases are asymmetrical. Seven patients showed asymmetrical hyperostosis, of which 6 cases involved medulla. There was no fat infiltration. There were 5 cases showed peripheral soft tissue edema, of which 1 case involving adjacent muscles. All of the 9 cases were accompanied by multiple peripheral lymph nodes. One case underwent diffusion weighted imaging examination, and there was no obvious diffusion limitation in the lesion area.Conclusions: Magnetic resonance imaging can clearly show the range and degree of mandible involvement in SAPHO syndrome, which has certain characteristics, and providing help for clinical diagnosis and follow-up.
[Keywords] SAPHO syndrome；magnetic resonance imaging；mandible；case report

YU Meiyan Department of Radiology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China

ZHANG Ya’nan Department of Radiology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China

REN Mengmeng Department of Radiology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China

HONG Yueying Department of Radiology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China

LI Junqiu Department of Radiology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China

LI Chen Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Beijing 100005, China

LU Xinyu Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China

ZHANG Wen Department of Rheumatology and Immunology, Peking Union Medical College Hospital, Beijing 100005, China

HUO Jianwei* Department of Radiology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China

*Correspondence to: Huo JW, E-mail: huojw1234@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Key R & D Program Rare Disease Clinical Cohort Study Project No. 2016FYC0901500 CAMS Innovation Fund for Medical Sciences (CIFMS) No.2017-I2M-3-001
Received  2020-08-02
Accepted  2020-11-26
DOI: 10.12015/issn.1674-8034.2020.12.014
Cite this article as: Yu MY, Zhang YN, Ren MM, et al. Magnetic resonance imaging findings of jaw in 9 patients with SAPHO syndrome. Chin J Magn Reson Imaging, 2020, 11(12): 1148-1151. DOI:10.12015/issn.1674-8034.2020.12.014.

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