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• Health for all, Prosperity for all •
The value of conventional MRI combined with apparent diffusion coefficient in differential diagnosis of orbital tumors
LI Feng  LIU Ke  SUN Guolong 

Cite this article as: Li F, Liu K, Sun GL. The value of conventional MRI combined with apparent diffusion coefficient in differential diagnosis of orbital tumors. Chin J Magn Reson Imaging, 2020, 11(12): 1163-1166. DOI:10.12015/issn.1674-8034.2020.12.018.


[Abstract] Objective: To investigate the value of conventional MRI measurement combined with apparent diffusion coefficient (ADC) in the differential diagnosis of orbital tumor.Materials and Methods: A total of 25 patients with orbital mass confirmed by pathological examination received diffusion weighted imaging (DWI) and MRI scanning in our hospital from August 2016 to October 2019. The structural MRI imaging characteristics (tumor location, boundary, involved range, signal intensity, and upper space effect of T2WI) were retrospectively analyzed. ADC value and signal ratio (CER) between the tumor itself and the peripheral temporal muscle after enhancement were measured. T-test and chi-square test were used to compare qualitative and quantitative results of benign and malignant orbital masses. ROC curve was used to analyze the diagnostic efficacy of each diagnostic index for orbital benign and malignant tumors.Results: In this group of 25 patients with orbital tumors, 18 were malignant and 7 were benign. The efflux effect was observed in 7 patients with malignant tumors and 6 patients with benign tumors, there was a statistical difference between the two groups (P<0.05). There were no statistically significant differences in the location, boundary, involved range and signal intensity of benign and malignant tumors (P>0.05). The ADC and CER values of the benign and malignant tumor groups were (1.31±0.33)×10-3 mm2/s, 1.75±0.29, (0.81±0.11)×10-3 mm2/s, 1.42±0.15, respectively, with statistically significant differences between the two groups (P<0.05).The optimal diagnostic threshold of orbital malignant tumor was ADC value 0.75×10-3 mm2/s, AREA under ROC was 0.820, sensitivity and specificity were 87.1% and 94.3%, respectively. The area under ROC was 0.965, and the sensitivity and specificity were 83.6% and 100.0%, respectively.Conclusions: Conventional MRI combined with ADC value has a good value for the differential diagnosis of orbital tumor.
[Keywords] orbital tumor；magnetic resonance imaging；diffusion-weighted imaging；apparent diffusion coefficient

LI Feng* Department of Imaging, Zhuhai Integrated Traditional Chinese and Western Medicine Hospital, Zhuhai 519000, China

LIU Ke Department of Radiology, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China

SUN Guolong Department of Imaging, Zhuhai Integrated Traditional Chinese and Western Medicine Hospital, Zhuhai 519000, China

*Correspondence to: Li F, E-mail: qhlme9382172651@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Guangdong Medical Science and Technology Research Fund No.WSTJJ2013122937091197401226419
Received  2020-08-25
Accepted  2020-12-03
DOI: 10.12015/issn.1674-8034.2020.12.018
Cite this article as: Li F, Liu K, Sun GL. The value of conventional MRI combined with apparent diffusion coefficient in differential diagnosis of orbital tumors. Chin J Magn Reson Imaging, 2020, 11(12): 1163-1166. DOI:10.12015/issn.1674-8034.2020.12.018.

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