Share:
Share this content in WeChat
X
Health for all, Prosperity for all
MR pulmonary angiography in patients with pulmonary embolism and its correlation with right heart function and prognosis
WANG Mingfu  XU Wei 

Cite this article as: Wang MF, Xu W. MR pulmonary angiography in patients with pulmonary embolism and its correlation with right heart function and prognosis. Chin J Magn Reson Imaging, 2020, 11(12): 1178-1181. DOI:10.12015/issn.1674-8034.2020.12.022.


[Abstract] Objective: To investigate the characteristics of MR pulmonary angiography in patients with pulmonary embolism (PE) and its correlation with right heart function and prognosis assessment.Materials and Methods: A retrospective analysis was performed on 90 PE patients, who were divided into mild PE group, severe PE group, group with good prognosis and the group with poor prognosis according to their condition and prognosis. All patients underwent MR pulmonary angiography to calculate embolization score, perfusion defect score, right and left ventricular short axis maximum diameter ratio (RV/LV), and pulmonary artery diameter. To compare the features of MR pulmonary angiography in patients with different degrees of severity, as well as the differences in embolization score, perfusion defect score, RV/LV, and pulmonary artery diameter among different groups, and analyze their correlation, and analyze their prognostic value through ROC curve.Results: In mild PE patients, 254 segments (69.0%) of pulmonary artery branches showed blotchy and patchy filling defects by MR pulmonary angiography, which was significantly higher than that in severe PE group (P<0.05). MR angiography showed 306 pulmonary artery branches (95.6%) as subsegmental or segmental filling defects in the severe group, with a significantly higher incidence than that in the mild group (P<0.05). The embolization score, defect score, RV/LV and pulmonary artery diameter of severe PE group were significantly higher than those of mild PE group (P<0.05). The embolization score and defect score of the group with poor prognosis were significantly higher than that of the group with good prognosis (P<0.05). There was a significant positive correlation between embolization score and defect score, RV/LV, and pulmonary artery diameter (P<0.05). ROC curve analysis showed that the area under the curve of defect score and embolization score for PE prognosis were 0.911 (95% CI: 0.625—0.966) and 0.796 (95% CI: 0.800—1.000), respectively.Conclusions: MR pulmonary angiography can be used to evaluate the severity of PE, and it has a certain diagnostic value for the function and prognosis of right heart.
[Keywords] pulmonary embolism;magnetic resonance imaging;right ventricular function;pulmonary arteriography

WANG Mingfu* Departmengt of Radiology, the Third People’s Hospital of Hubei Province, Wuhan 430033, China

XU Wei Departmengt of Radiology, the Third People’s Hospital of Hubei Province, Wuhan 430033, China

*Correspondence to: Wang MF, E-mail: wangmingfu825@sina.com

Conflicts of interest   None.

Received  2020-08-25
Accepted  2020-11-15
DOI: 10.12015/issn.1674-8034.2020.12.022
Cite this article as: Wang MF, Xu W. MR pulmonary angiography in patients with pulmonary embolism and its correlation with right heart function and prognosis. Chin J Magn Reson Imaging, 2020, 11(12): 1178-1181. DOI:10.12015/issn.1674-8034.2020.12.022.

[1]
Meyer G, Vicaut E, Danays T, et al. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med, 2014, 370(15): 1402-1411. DOI: 10.1056/NEJMoa1302097.
[2]
Zhao LB, Jia ZY, Lu GD, et al. Establishment of a canine model of acute pulmonary embolism with definite right ventricular dysfunction through introduced autologous blood clots. Thromb Res, 2015, 135(4): 568-572. DOI: 10.1016/j.thromres.2015.01.016.
[3]
Voswinckel R, Hoeper MM, Kramm T, et al. Right heart failure in chronic pulmonary hypertension and acute pulmonary embolism. Internist, 2012, 53(5): 545-556. DOI: 10.1007/s00108-012-3017-6.
[4]
Thomas DM, McLaughlin PD, Nugent JP, et al. Evaluation of the proximal coronary arteries in suspected pulmonary embolism: diagnostic images in 51% of patients using non-gated, dual-source CT pulmonary angiography. Emerg Radiol, 2019, 26(2): 189-194. DOI: 10.1007/s10140-018-01661-0.
[5]
Hou DJ, Tso DK, Davison C, et al. Clinical utility of ultra high pitch dual source thoracic CT imaging of acute pulmonary embolism in the emergency department: are we one step closer towards a non-gated triple rule out?. Eur J Radiol, 2013, 82(10): 1793-1798. DOI: 10.1016/j.ejrad.2013.05.003.
[6]
Moore AJE, Wachsmann J, Chamarthy MR, et al. Imaging of acute pulmonary embolism: an update. Cardiovasc Diagn Ther, 2018, 8(3): 225-243. DOI: 10.21037/cdt.2017.12.01.
[7]
Chien CH, Shih FC, Chen CY, et al. Unenhanced multidetector computed tomography findings in acute central pulmonary embolism. BMC Med Imaging, 2019, 19(1): 65. DOI: 10.1186/s12880-019-0364-y.
[8]
Chae EJ, Seo JB, Jang YM, et al. Dual-energy CT for assessment of the severity of acute pulmonary embolism: pulmonary perfusion defect score compared with CT angiographic obstruction score and right ventricular/left ventricular diameter ratio. AJR Am J Roentgenol, 2010, 194(3): 604-610. DOI: 10.2214/AJR.09.2681.
[9]
Barrios D, Rosa-Salazar V, Jiménez D, et al. Right heart thrombi in pulmonary embolism. Eur Respir J, 2016, 48(5): 1377-1378. DOI: 10.1183/13993003.01044-2016.
[10]
Pontana F, Henry S, Duhamel A, et al. Impact of iterative reconstruction on the diagnosis of acute pulmonary embolism (PE) on reduced-dose chest CT angiograms. Eur Radiol, 2015, 25(4): 1182-1189. DOI: 10.1007/s00330-014-3393-5.
[11]
蒲艳军,何芬,李文玲,等.双源CT灌注缺损评分评价急性肺栓塞严重程度的临床应用.中国医学影像技术, 2015, 31(10): 1540-1544. DOI: 10.13929/j.1003-3289.2015.10.023.
[12]
Mao X, Wang S, Jiang X, et al. Diagnostic value of dual-source computerized tomography combined with perfusion imaging for peripheral pulmonary embolism. Iranian J Radiol, 2016, 13(2): e29402. DOI: 10.5812/iranjradiol.29402.
[13]
Qanadli SD, El HM, Vieillard-Baron A, et al. New CT index to quantify arterial obstruction in pulmonary embolism: comparison with angiographic index and echocardiography. AJR Am J Roentgenol, 2001, 176(6): 1415-1420.
[14]
Cascio V, Hon M, Haramati LB, et al. Imaging of suspected pulmonary embolism and deep venous thrombosis in obese patients. Br J Radiol, 2018, 91(1089): 20170956. DOI: 10.1259/bjr.20170956
[15]
Zhang LJ, Zhao YE, Wu SY, et al. Pulmonary embolism detection with dual-energy CT: experimental study of dual-source CT in rabbits. Radiology, 2009, 252(1): 61-70. DOI: 10.1038/s41598-018-20254-y.
[16]
宋晶,陈友三,孔祥闯,等.肺动脉高压患者左室心肌应变的MRI研究.临床放射学杂志, 2020, 39(5): 913-918. DOI: 10.13437/j.cnki.jcr.2020.05.015.
[17]
Petritsch B, Kosmala A, Gassenmaier T, et al. Diagnosis of pulmonary artery embolism: Comparison of single-source CT and 3rd generation dual-source CT using a dual-energy protocol regarding image quality and radiation dose. Rofo, 2017, 189(6): 527-536. DOI: 10.1055/s-0043-103089.
[18]
Zhou Y, Shi H, Wang Y, et al. Assessment of correlation between CT angiographic clot load score, pulmonary perfusion defect score and global right ventricular function with dual-source CT for acute pulmonary embolism. Br J Radiol, 2012, 85(1015): 972-979. DOI: 10.1259/bjr/40850443.
[19]
Abdellatif W, Esslinger E, Kobes K, et al. Acquisition time, radiation dose, subjective and objective image quality of dual-source CT scanners in acute pulmonary embolism: a comparative study. Eur Radiol, 2020, 30(5): 2712-2721. DOI: 10.1007/s00330-019-06650-6.
[20]
Zhang LJ, Zhao YE, Wu SY, et al. Pulmonary embolism detection with dual-energy CT: experimental study of dual-source CT in rabbits. Radiology, 2009, 252(1): 61-70. DOI: 10.1148/radiol.2521081682.

PREV The differential diagnosis of benign and malignant breast tumors with MRI quantitative and semi-quantitative parameters and the correlation analysis with biological indicators of breast cancer
NEXT Analysis of the diagnostic efficacy of T2WI combined with DWI and DCE-MRI in peripheral chronic prostatitis and prostatic cancer
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn