Share：
Share this content in WeChat
X
[Chinese][PDF]823115
• Health for all, Prosperity for all •
Imaging evaluation of lumbar spine in middle-aged and elderly patients using MR fat quantification technique combined with quantitative computed tomography
MA Peiqi  YUAN Yushan  PENG Bin  ZHANG Zongxi  ZHANG Lei  ZHANG Yang  ZHANG Xiaoyan  WANG Zhongqiu 

Cite this article as: Ma PQ, Yuan YS, Peng B, et al. Imaging evaluation of lumbar spine in middle-aged and elderly patients using MR fat quantification technique combined with quantitative computed tomography. Chin J Magn Reson Imaging, 2020, 11(12): 1186-1189. DOI:10.12015/issn.1674-8034.2020.12.024.


[Abstract] Objective: To investigate the correlation between fat fraction (FF), R2* and bone mineral density (BMD) of lumbar vertebrae in middle-aged and elderly people of different genders.Materials and Methods: The FF and R2* values of each lumbar vertebra were measured by MRI fat quantitative technique (mDIXON-Quant), and quantitative computed tomography (QCT) was used to measure the BMD of each lumbar vertebra in 40 middle-aged and elderly patients (20 males and 20 females). The BMD, FF and R2* values of various lumbar vertebrae of different genders were compared by SNK test. The BMD, FF and R2* values of lumbar vertebrae of different genders were compared by t test. Pearson correlation analysis was conducted to analyze the correlation between FF and R2* values with BMD of each lumbar vertebrae of different genders.Results: The BMD and R2* value of each vertebral body between the middle-aged and elderly people in different genders showed no statistically significant difference (P>0.05). There were statistically significant differences in FF value of each vertebral body between the middle-aged and elderly people in different genders (P<0.05). The values of L4FF and L5FF were greater than L1FF in both male and female groups, and the value of L4FF in male group was greater than L2FF. There was no statistically significant difference in BMD and FF between male and female groups (P>0.05). There was statistically significant difference in R2* between male and female groups (P<0.05), and R2* in male group was greater than that in female group. The BMD and FF values of the lumbar spine in the middle-aged and elderly people of different genders were negatively correlated (rmale=-0.76, rfemale=-0.77, P<0.05), and were positively correlated with R2* value (rmale=0.56, rfemale=0.45, P<0.05).Conclusions: There was a certain correlation between lumbar body BMD with FF and R2* values in middle-aged and elderly people, and R2* values in middle-aged and elderly women were lower than those in men. Besides, the FF values in lower lumbar spine were higher than those in upper lumbar spine.
[Keywords] magnetic resonance imaging；quantitative computed tomography；bone mineral density；fat fraction；R2*

MA Peiqi Department of Medical Imaging, Fuyang People’s Hospital, Fuyang 236000, China

YUAN Yushan* Department of Medical Imaging, Fuyang People’s Hospital, Fuyang 236000, China

PENG Bin Department of Medical Imaging, Fuyang People’s Hospital, Fuyang 236000, China

ZHANG Zongxi Department of Medical Imaging, Fuyang People’s Hospital, Fuyang 236000, China

ZHANG Lei Department of Medical Imaging, Fuyang People’s Hospital, Fuyang 236000, China

ZHANG Yang Department of Medical Imaging, Fuyang People’s Hospital, Fuyang 236000, China

ZHANG Xiaoyan Department of Medical Imaging, Fuyang People’s Hospital, Fuyang 236000, China

WANG Zhongqiu Department of Medical Imaging, Fuyang People’s Hospital, Fuyang 236000, China

*Correspondence to: Yuan YS, E-mail: fysyyyys@163.com

Conflicts of interest   None.

Received  2020-08-26
Accepted  2020-11-14
DOI: 10.12015/issn.1674-8034.2020.12.024
Cite this article as: Ma PQ, Yuan YS, Peng B, et al. Imaging evaluation of lumbar spine in middle-aged and elderly patients using MR fat quantification technique combined with quantitative computed tomography. Chin J Magn Reson Imaging, 2020, 11(12): 1186-1189. DOI:10.12015/issn.1674-8034.2020.12.024.

[1]
Cheng XG, Li K, Ou SX, et al. Heterogeneity in spinal bone mineral density among young adults from three astern provincial capital cities in mainland china. J Clin Densitom, 2017, 20(2): 198-204. DOI: 10.1016/j.jocd.2016.03.009.
[2]
程晓光，王亮，曾强,等.中国定量CT骨质疏松症诊断指南(2018).中国骨质疏松杂志, 2019, 25(6): 733-773. DOI: 10.3969/j.issn.1006-7108.2019.06.001.
[3]
翟建，吴雅琳，胡琴,等.基于定量CT对不同性别、年龄人群血尿酸与腰椎骨密度的相关性分析.放射学实践, 2020, 35(3): 385-388. DOI: 10.13609/j.cnki.1000-0313.2020.03.024.
[4]
王翔，屈瑾，雷新玮.慢性冈上肌腱损伤肌肉萎缩及脂肪浸润的定量研究.国际医学放射学杂志, 2017, 40(4): 391-394. DOI: 10.19300/j.2017.L5163zt.
[5]
Baum T, Cordes C, Dieckmeyer M, et al. MR-based assessment of body fat distribution and characteristics. Eur J Radiol, 2016, 85(8): 1512-1518. DOI: 10.1016/j.ejrad.2016.02.013.
[6]
Li G, Xu Z, Yuan W, et al. Short-and midterm reproducibility of marrow fat measurements using mDixon imaging in healthy postmenopausal women. Skeletal Radiol, 2016, 45(10): 1385-1390. DOI: 10.1007/s00256-016-2448-x.
[7]
Paccou J, Hardouin P, Cotten A, et al. The role of bone marrow fat in skeletal health: usefulness and perspectives for clinicians. J Clin Endocrinol Metab, 2015, 100(10): 3613-3621. DOI: 10.1210/jc.2015-2338.
[8]
Bertheau RC, Lorbeer R, Nattenmüller J, et al. Bone marrow fat fraction assessment in regard to physical activity: KORA FF4-3-T MR imaging in a population-based cohort. Eur Radiol, 2020, 30(6): 3417-3428. DOI: 10.1007/s00330-019-06612-y.
[9]
张勇，程晓光，于爱红,等.腰椎椎体骨髓脂肪含量与骨密度、年龄关系的定量影像评估.中华放射学杂志, 2017, 51(10): 771-776. DOI: 10.3760/cma.j.issn.1005-1201.2017.10.010.
[10]
Karampinos DC, Ruschke S, Gordijenko O, et al. Association of MRS-based vertebral bone marrow fat fraction with bone strength in a human in vitro model. J Osteoporos, 2015, 2015: 1-8. DOI: 10.1155/2015/152349.
[11]
李轶雯，袁慧书.磁共振脂肪定量技术在骨质疏松症中的应用.中国医学影像学杂志, 2017, 51(1): 52-55. DOI: 10.3969/j.issn.1005-5185.2017.01.015.
[12]
Kühn JP, Hernando D, Meffert PJ, et al. Proton-density fat fraction and simultaneous R2* stimation as an MRI tool for assessment of osteoporosis. Eur Radiol, 2013, 23(12): 3432-3439. DOI: 10.1007/s00330-013-2950-7.
[13]
代岳，王姗，徐慧婷,等. IDEAL-IQ技术对不同年龄椎体骨髓脂肪含量的定量评价.中国医学计算机成像杂志, 2017, 23(2): 161-165. DOI: 10.19627/j.cnki.cn31-1700/th.2017.02.012.
[14]
Ojanen X, Borra RJ, Havu M, et al. Comparison of vertebral bone marrow fat assessed by 1H MRS and inphase and out-of-phase MRI among family members. Osteoporos Int, 2014, 25(2): 653-662. DOI: 10.1007/s00198-013-2472-9.
[15]
张振，李青华，王娟,等. 3.0 T MR IDEAL-IQ序列对成年女性腰椎脂肪含量测量及临床价值.中国医学计算机成像杂志, 2020, 26(1): 51-54. DOI: 10.19627/j.cnki.cn31-1700/th.2020.01.011.
[16]
张晓东，李勉文，卢雄光,等.骨髓脂肪含量沉积及微循环变化与椎间盘退变相关性初步研究.中华放射学杂志, 2017, 51(10): 766-770. DOI: 10.3760/cma.j.issn.1005-1201.2017.10.009.
[17]
邓小丽，杨莉，陈思浩,等.常规MRI在骨质疏松诊断中的价值.磁共振成像, 2020, 11(8): 663-665. DOI: 10.12015/issn.1674-8034.2020.08.014.
[18]
冯红梅，洪居陆，陈婉雯,等.腰椎脂肪含量、R2*与骨密度及年龄的相关性.中国医学影像学杂志, 2019, 27(4): 302-304. DOI: 10.3969/j.issn.1005-5185.2019.04.015.
[19]
常飞霞，黄刚，樊敦徽,等.磁共振水-脂分离成像技术对椎体脂肪含量的测量.磁共振成像, 2016, 7(12): 902-908. DOI: 10.12015/issn.1674-8034.2016.12.003.
[20]
张伟，王兵，张林林,等.绝经后股骨颈骨折股骨头骨铁含量、血清铁蛋白与骨密度相关性研究.中华骨科杂志, 2014, 34(1): 39-47. DOI: 10.3760/cma.j.issn.0253-2352.2014.01.008.
[21]
刘栋，孙永明，华俊,等.胸、腰椎骨质疏松性骨折患者椎体骨铁含量、血清铁蛋白与骨密度的相关性.中华骨质疏松和骨矿盐疾病杂志, 2017, 10(2): 104-109. DOI: 10.3969/j.issn.1674-2591.2017.02.002.
[22]
Griffith JF, Yeung DK, Ma HT, et al. Bone marrow fat content in the elderly: a reversal of sex difference seen in younger subjects. J Magn Reson Imaging, 2012, 36(1): 225-230. DOI: 10.1002/jmri.23619.

PREV Analysis of the diagnostic efficacy of T2WI combined with DWI and DCE-MRI in peripheral chronic prostatitis and prostatic cancer
NEXT MRI diagnosis of early Sturge—Weber syndrome with glaucoma as the first symptom: A case report
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn