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• CLINICAL ARTICLE •
Correlation between pancreatic fat deposition and abdominal fat distribution and essential hypertension based on MRI
ZHANG Qinhe  LIU Ailian  YANG Jie  YOU Yaru  CHEN Lihua  SONG Qingwei  SHEN Zhiwei  XIE Lizhi 

Cite this article as: Zhang QH, Liu AL, Yang J, et al. Correlation between pancreatic fat deposition and abdominal fat distribution and essential hypertension based on MRI[J]. Chin J Magn Reson Imaging, 2021, 12(1): 43-47, 52. DOI:10.12015/issn.1674-8034.2021.01.009.


[Abstract] Objective To investigate the association of pancreatic fat with visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), and hypertension.Materials and Methods A total of 54 patients with hypertension and 108 control subjects who underwent an upper abdomen MRI scan with IDEAL-IQ sequence were included. Pancreatic tissue was segmented and whole pancreatic fat fraction (FF) were measured. VAT and SAT area were measured. VAT and SAT FF were recorded. Visceral/subcutaneous adipose tissue area ratio (V/S) was also calculated.Results Patients with hypertension had higher whole pancreatic FF, VAT area, SAT area, V/S, VAT FF and SAT FF. Whole pancreatic FF has the highest diagnostic value in detecting hypertension (area under the curve, 0.816). The threshold of whole pancreatic FF of 10.15% showed a sensitivity of 75.9% and specificity of 81.5% for hypertension. Whole pancreatic FF showed a moderate correlation with VAT area (r＝0.541) and VAT FF (r＝0.561) and a weak correlation with SAT area (r＝0.280), SAT FF (r＝0.324) and V/S (r＝0.266).Conclusions Hypertension is associated with higher whole pancreatic FF, VAT and SAT. Both increased area and FF of VAT and SAT are positively correlated with whole pancreatic FF.
[Keywords] hypertension；pancreas fat；visceral adipose tissue；subcutaneous adipose tissue；magnetic resonance imaging

ZHANG Qinhe1   LIU Ailian1*   YANG Jie1   YOU Yaru1   CHEN Lihua1   SONG Qingwei1   SHEN Zhiwei2   XIE Lizhi3  

1 Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

2 Philips Healthcare, Beijing 100000, China

3 General Electric Medical Magnetic Resonance Products Department, Beijing 10000, China

*Corresponding author: Liu AL, E-mail: liuailian@dmu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS  Capital Science and Technology Leading Talent Training Project No. Z181100006318003
Received  2020-09-14
Accepted  2020-11-30
DOI: 10.12015/issn.1674-8034.2021.01.009
Cite this article as: Zhang QH, Liu AL, Yang J, et al. Correlation between pancreatic fat deposition and abdominal fat distribution and essential hypertension based on MRI[J]. Chin J Magn Reson Imaging, 2021, 12(1): 43-47, 52. DOI:10.12015/issn.1674-8034.2021.01.009.

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