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• CLINICAL ARTICLE •
Cerebral microstructural changes of the motor aphasia after stroke using diffusion tensor imaging
LUO Qiaoya  HAN Bingyan  XI Yanling  WANG Yunling 

Cite this article as: Luo QY, Han BY, Xi YL, et al. Cerebral microstructural changes of the motor aphasia after stroke using diffusion tensor imaging[J]. Chin J Magn Reson Imaging, 2021, 12(2): 10-14. DOI:10.12015/issn.1674-8034.2021.02.003.


[Abstract] Objective To evaluate the changes of brain microstructure in language functional areas of Broca aphasia after stroke using diffusion tensor imaging (DTI). Materials andMethods Collect 15 cases for the first time in our hospital after ischemic stroke with Broca aphasia included in the case group, and collect the normal healthy volunteers 15 cases included in the healthy controls. Two groups proceed head scan and DTI scan, then fractional anisotropy (FA), mean diffusivity (MD), and bundle path graph are obtained after processing the obtained images and compare FA values, MD values and fiber bundle line analysis between the two groups.Results The FA value of Broca area on the left of the case group was 0.357±0.020, and that of the normal control group was 0.396±0.010. The FA values of Broca area on the left of the case group were significantly lower than those of the normal control group (t=-7.22, P=0.00). The FA value of the affected side of the case group was 0.361±0.020, and that of the contralateral mirror area was 0.406±0.010. The FA value of the case group was lower than that of the contralateral mirror area (t=-9.40, P=0.00), and the difference was statistically significant (P＜0.05). And the MD value of Broca area on the left of the case group was 1.091±0.084, the MD value of the affected side of the case group was 1.098±0.100, the MD value of the left Broca healthy controls was 0.797±0.048, and that of the contralateral mirror area was 0.808±0.030. The MD values of Broca area on the left of the case group and the affected side of the case group were higher than the normal control group (t=11.61, P=0.00) and the contralateral side mirror area (t=9.84, P=0.00).The difference is statistically significant (P＜0.05). The fiber bundles in the infarcted area were sparse and deficient in different degrees compared with the contralateral area.Conclusions DTI technology can provide imaging diagnosis basis for patients with Broca aphasia after stroke, and provide certain basis for clinical treatment and rehabilitation prognosis.
[Keywords] stroke；broca aphasia；diffusion tensor imaging；cerebral structural；magnetic resonance imaging

LUO Qiaoya1   HAN Bingyan1   XI Yanling2   WANG Yunling2*  

1 Department of Imaging, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

2 The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

Wang YL, E-mail: 1079806994@qq.com

Conflicts of interest   None.

ACKNOWLEDGENTS This work was part of National Natural Science Foundation of China (No.81660379).
Received  2020-08-23
Accepted  2020-11-18
DOI: 10.12015/issn.1674-8034.2021.02.003
Cite this article as: Luo QY, Han BY, Xi YL, et al. Cerebral microstructural changes of the motor aphasia after stroke using diffusion tensor imaging[J]. Chin J Magn Reson Imaging, 2021, 12(2): 10-14. DOI:10.12015/issn.1674-8034.2021.02.003.

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