Share：
Share this content in WeChat
X
[Chinese][PDF]134185
• CLINICAL ARTICLE •
The reasearch of basilar artery based on high-resolution magnetic resonance imaging in patients with posterior circulation ischemic attack
ZHOU Yingxue  CUI Yingzhe  NAN Dong  CHEN Yanfei  LIU Pengfei 

Cite this article as: Zhou YX, Cui YZ, Nan D, et al. The reasearch of basilar artery based on high-resolution magnetic resonance imaging in patients with posterior circulation ischemic attack[J]. Chin J Magn Reson Imaging, 2021, 12(2): 15-18, 23. DOI:10.12015/issn.1674-8034.2021.02.004.


[Abstract] Objective The differences of basilar artery vessel wall between frequent patients and non-frequent patients with transient ischemic attack (TIA) were analyzed using high-resolution magnetic resonance imaging (HR-MRI). Materials andMethods The patients were scanned by three-dimension time of flight magnetic resonance angiography (3D-TOF-MRA) of the head and HR-MRI of basilar artery, and the patients with plaques were enrolled in the study. According to the frequency of TIA within 24 hours, the patients were divided into the frequent group (≥2) and the non-frequent group (＜2). The plaque morphological indexes, degree of stenosis, remodeling index, plaque distribution and clinical characteristics between the two groups were analyzed.Results Sixty-eight patients with TIA (38 cases in the frequent group and 30 cases in the non-frequent group) had a total of 184 plaques (108 in the frequent group and 76 in the non-frequent group). At the maximal-lumen-narrowing site, the plaque morphological indexes in the frequent group were significantly different from those in the non-frequent group (P＜0.05). The degree of stenosis and remodeling index in the frequent group were higher than those in the non-frequent group, and the differences were statistically significant (P＜0.05). The plaques located at ventral wall of the frequent group (38.0%) accounted for a higher proportion as compared with the non-frequent group (22.4%)(P=0.025), and the plaques located at dorsal wall of the frequent group (17.6%) accounted for a lower proportion as compared with the non-frequent group (35.5%)(P=0.006). The proportion of lateral wall plaques in the frequent group (44.4%) was similar to that in the non-frequent group (42.1%), with no statistically significant difference (P=0.753). The clinical characteristics had no statistically significant differences between the two groups (P＞0.05).Conclusions Most of the plaques are distributed on the ventral side in the frequent group and on the dorsal side in the non-frequent group, and the proportion of lateral plaques are similar between the two groups. In the frequent group, plaque burden is higher, artery stenosis is more severe, and the remodeling index is higher. Plaques in the non-frequent group are relatively more stable.
[Keywords] high-resolution；magnetic resonance imaging；plaque；atherosclerotic；transient ischemic attack

ZHOU Yingxue   CUI Yingzhe   NAN Dong   CHEN Yanfei   LIU Pengfei*  

Department of Magnetic Resonance, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

Liu PF, E-mail: liup.fei@163.com

Conflicts of interest   None.

Received  2020-07-02
Accepted  2020-08-04
DOI: 10.12015/issn.1674-8034.2021.02.004
Cite this article as: Zhou YX, Cui YZ, Nan D, et al. The reasearch of basilar artery based on high-resolution magnetic resonance imaging in patients with posterior circulation ischemic attack[J]. Chin J Magn Reson Imaging, 2021, 12(2): 15-18, 23. DOI:10.12015/issn.1674-8034.2021.02.004.

1
Feng XY, Chan KL, Lan LF, et al. Stroke mechanisms in symptomatic intracranial atherosclerotic disease: Classification and clinical implications[J]. Stroke, 2019, 50(10): 2692-2699. DOI: 10.1161/STROKEAHA.119.025732.
2
Aurélien Quenault, Martinez de Lizarrondo Sara, Olivier Etard, et al. Molecular magnetic resonance imaging discloses endothelial activation after transient ischaemic attack[J]. Brain, 2017, 140(1): 146-157. DOI: 10.1093/brain/aww260.
3
Jing J, Meng X, Zhao XQ, et al. Dual antiplatelet therapy in transient ischemic attack and minor stroke with different infarction patterns: Subgroup analysis of the CHANCE randomized clinical trial[J]. JAMA Neurol, 2018, 75(6): 711-719. DOI: 10.1001/jamaneurol.2018.0247.
4
Guo RC, Zhang XB, Zhu XJ, et al. Morphologic characteristics of severe basilar artery atherosclerotic stenosis on 3D high-resolution MRI[J]. BMC Neurol, 2018, 18(1): 206. DOI: 10.1186/s12883-018-1214-1.
5
Kim DK, Verdoorn Jared T, Gunderson Tina M, et al. Comparison of non-contrast vessel wall imaging and 3-D time-of-flight MRA for atherosclerotic stenosis and plaque characterization within intracranial arteries[J]. J Neuroradiol, 2020, 47(4): 266-271. DOI: 10.1016/j.neurad.2019.05.003.
6
Adhithyan R, Kesav P, Thomas B, et al. High-resolution magnetic resonance vessel wall imaging in cerebrovascular diseases[J]. Neurol India, 2018, 66(4): 1124-1132. DOI: 10.4103/0028-3886.236964.
7
Mandell DM, Mossa-Basha M, Qiao Y, et al. Intracranial vessel wall MRI: Principles and expert consensus recommendations of the American society of neuroradiology[J]. AJNR Am J Neuroradiol, 2017, 38(2): 218-229. DOI: 10.3174/ajnr.A4893.
8
Qiao Y, Anwar Zeeshan, Intrapiromkul J, et al. Patterns and implications of intracranial arterial remodeling in stroke patients[J]. Stroke, 2016, 47(2): 434-440. DOI: 10.1161/STROKEAHA.115.009955.
9
Schoenhagen P, Ziada KM, Kapadia SR, et al. Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intravascular ultrasound study[J]. Circulation, 2000, 101(6): 598-603. DOI: 10.1161/01.cir.101.6.598.
10
Liao SY, Deng ZZ, Wang YG, et al. Different mechanisms of two subtypes of perforating artery infarct in the middle cerebral artery territory: A high-resolution magnetic resonance imaging study[J]. Front Neurol, 2018, 9: 657. DOI: 10.3389/fneur.2018.00657.
11
Rodriguez-Granillo GA, Serruys PW, Garcia-Garcia HM, et al. Coronary artery remodelling is related to plaque composition[J]. Heart, 2006, 92(3): 388-391. DOI: 10.1136/hrt.2004.057810.
12
Ma N, Jiang WJ, Lou X, et al. Arterial remodeling of advanced basilar atherosclerosis: a 3-tesla MRI study[J]. Neurology, 2010, 75(3): 253-258. DOI: 10.1212/WNL.0b013e3181e8e714.
13
Wexberg P, Gyöngyösi M, Sperker W, et al. Pre-existing arterial remodeling is associated with in-hospital and late adverse cardiac events after coronary interventions in patients with stable angina pectoris[J]. J Am Coll Cardiol, 2000, 36(6): 1860-1869. DOI: 10.1016/s0735-1097(00)00949-9.
14
Li F, Chen QX, Chen ZB, et al. Magnetic resonance imaging of plaque burden in vascular walls of the middle cerebral artery correlates with cerebral infarction[J]. Curr Neurovasc Res, 2016, 13(4): 263-270. DOI: 10.2174/1567202613666160829095324.
15
Wannarong Thapat, Parraga Grace, Buchanan Daniel, et al. Progression of carotid plaque volume predicts cardiovascular events[J]. Stroke, 2013, 44(7): 1859-1865. DOI: 10.1161/STROKEAHA.113.001461.
16
Yu J, Li ML, Xu YY, et al. Plaque distribution of low-grade basilar artery atherosclerosis and its clinical relevance[J]. BMC Neurol, 2017, 17(1): 8. DOI: 10.1186/s12883-016-0785-y.
17
Huang B, Yang WQ, Liu XT, et al. Basilar artery atherosclerotic plaques distribution in symptomatic patients: a 3.0 T high-resolution MRI study[J]. Eur J Radiol, 2013, 82(4): 199-203. DOI: 10.1016/j.ejrad.2012.10.031.

PREV Cerebral microstructural changes of the motor aphasia after stroke using diffusion tensor imaging
NEXT The diagnostic value of IVIM in glioma grading and its correlation with Ki-67 labeling index
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn