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Compared study of the cerebral artery stenosis assessed by ZTE-MRA and TOF-MRA
QI Xin  SHA Lin  LÜ Jianbo  PAN Yuanyi 

Cite this article as: Qi X, Sha L, Lü JB, et al. Compared study of the cerebral artery stenosis assessed by ZTE-MRA and TOF-MRA[J]. Chin J Magn Reson Imaging, 2021, 12(2): 70-73. DOI:10.12015/issn.1674-8034.2021.02.016.


[Abstract] Objective To compare the image quality and the diagnostic value of zero-echo-time MR angiography (ZTE-MRA) and time-of-flight MR angiography (TOF-MRA) in the evaluation of cerebral artery stenosis. Materials andMethods Nineteen cases of cerebral artery stenosis were examined by ZTE-MRA and TOF-MRA at the same time. DSA examination was conducted within one week of MRA examination, to evaluate the accuracy, reliability and specificity of ZTE MRA and TOF-MRA.Results Among the images obtained by ZTE-MRA and TOF-MRA, the proportion of the images with good score was 84% and 74%. There was no significant difference in the image quality score between the two methods (P>0.05). The average SNR of ZTE-MRA and TOF-MRA were 14.2 and 19.4, respectively. The rank sum test of the two groups of independent samples showed no statistical difference (P>0.05). Based on the diagnosis of cerebral artery stenosis, the sensitivity and specificity of ZTE-MRA were 100% and 98%. The sensitivity and specificity of TOF-MRA in the diagnosis of cerebral arterial stenosis were 85% and 96%, respectively. Compared the consistency of TOF-MRA and DSA, the Kappa value was 0.776, indicating a good consistency between the two. The accuracy rate of grade 1—2 and grade 3—4 arterial stenosis diagnosed by ZTE-MRA was 57% and 81%. Among the TOF-MRA, the accuracy rate of grade 1—2 and grade 3—4 arterial stenosis was 46% and 31%. There was no statistical difference between the two methods in the diagnosis of grade 1—2 arterial stenosis (P>0.05), and there was statistical difference between the two methods in the diagnosis of grade 3—4 arterial stenosis (P<0.05).Conclusions ZTE-MRA had comparative image quality with TOF-MRA. There was no significant difference between the two methods in the diagnosis of grade 1—2 cerebral arterial stenosis. ZTE-MRA had high value in the diagnosis of grade 3—4 cerebral artery stenosis, accuracy is higher than TOF-MRA.
[Keywords] magnetic resonance angiography;cerebral artery stenosis;zero echo time MR angiography;time of fight MR angiography;digital subtraction angiography

QI Xin1   SHA Lin1   LÜ Jianbo1   PAN Yuanyi2*  

1 Department of Radiology, the Second Hospital of Dalian Medical University, Dalian 116027, China

2 Department of Radiology, Guizhou Provincial People's Hospital, Guiyang 550000, China

Pan YY, E-mail: 872524179@qq.com

Conflicts of interest   None.

Received  2020-11-07
Accepted  2021-01-11
DOI: 10.12015/issn.1674-8034.2021.02.016
Cite this article as: Qi X, Sha L, Lü JB, et al. Compared study of the cerebral artery stenosis assessed by ZTE-MRA and TOF-MRA[J]. Chin J Magn Reson Imaging, 2021, 12(2): 70-73. DOI:10.12015/issn.1674-8034.2021.02.016.

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