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• EXPERIENCE EXCHANGES •
Application of apparent diffusion coefficient histogram analysis in the grading of gastrointestinal stromaltumors
CHEN Tingting  WEI Mingxiang  ZHU Yan  BAI Genji 

Cite this article as: Chen TT, Wei MX, Zhu Y, et al. Application of apparent diffusion coefficient histogram analysis in the grading of gastrointestinal stromaltumors[J]. Chin J Magn Reson Imaging, 2021, 12(2): 79-82. DOI:10.12015/issn.1674-8034.2021.02.018.


[Abstract] Objective To study the application value of tumors volume based apparent diffusion coefficient (ADC) histogram analysis in grading diagnosis of gastrointestinal stromal tumor. Materials andMethods Forty-four patients with gastrointestinal stromal tumors were retrospectively analyzed, including 12 cases of very low-risk and low-risk group, 9 cases of middle-risk group, and 23 cases of high-risk group. Regions of interest (ROI) in the apparent diffusion coefficient maps of three groups on each layer of tumor level were drawn by using 3D Slicer software and were analyzed using the whole tumors gray histogram. ROC curve analysis was used to assess the diagnostic performance of ADC histogram in distinguishing the three groups.Results Through histogram analysis of 11 parameters, two parameters were statistically significant (P＜0.05), including minimum and perc.10%. The remaining 9 parameters had no significant difference between the three groups (P＞0.05). Between the very low-risk and low-risk group and the middle-risk, the sensitivity of minimun was 88.89%, the specificity was 58.33%, the area under the curve was 0.750, and the best cut-off value was 0. Between the middle-risk and high-risk, the sensitivity of perc.10% was 91.3%, the specificity was 44.44%, the area under the curve was 0.638, and the best cut-off value was 1021. Between the very low-risk and low-risk group and the high-risk, the sensitivity of minimun was 91.3%, the specificity was 66.67%, the area under the curve was 0.786, and the best cut-off value was 1021.Conclusions Histograms analysis of ADC maps could provide ancillary diagnosis value in grading diagnosis of gastrointestinal stromal tumors. Minimun and perc.10% had a identification diagnostic efficiency.
[Keywords] apparent diffusion coefficient；magnetic resonance imaging；histogram analysis；ROC curve；gastrointestinal stromal tumor；risk rating

CHEN Tingting1, 2   WEI Mingxiang3   ZHU Yan3   BAI Genji1*  

1 The First People's Hospital of Huaian, the Huaian Clinical College of Xuzhou Medical University, Huaian 223300, China

2 Huaian Huaiyin Hospital, Huaian 223300, China

3 The First People's Hospital of Huaian, the First Huaian Hospital Affiliated to Nanjing Medical University, Huaian 223300, China

Bai GJ, E-mail: hybgj0451@163.com

Conflicts of interest   None.

Received  2020-08-24
Accepted  2021-01-12
DOI: 10.12015/issn.1674-8034.2021.02.018
Cite this article as: Chen TT, Wei MX, Zhu Y, et al. Application of apparent diffusion coefficient histogram analysis in the grading of gastrointestinal stromaltumors[J]. Chin J Magn Reson Imaging, 2021, 12(2): 79-82. DOI:10.12015/issn.1674-8034.2021.02.018.

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