The feasibility study of diffusion weighted magnetic resonance imaging in predicting peritoneal cancer index in patients with advanced ovarian cancer

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WAN Zaixin LU Yubo LI Dan

Cite this article as: Wan ZX, Lu YB, Li D. The feasibility study of diffusion weighted magnetic resonance imaging in predicting peritoneal cancer index in patients with advanced ovarian cancer[J]. Chin J Magn Reson Imaging, 2021, 12(2): 83-85. DOI:10.12015/issn.1674-8034.2021.02.019.

Abstract

[Abstract] Objective To evaluate the potential of diffusion weighted MRI in predicting peritoneal cancer index (PCI) in patients with advanced ovarian cancer and whether patients can perform complete tumor cell extinction. Materials andMethods We retrospectively included 25 patients with advanced ovarian cancer (FIGO stage IIb and above) who received cytoreductive surgery at Dandong Traditional Chinese Medicine Hospital from June 2016 to May 2018. Included patients underwent a 1.5 T magnetic resonance diffusion-weighted imaging scan before surgery [the scan sequence in DW-MRI examination includes T1 and T2-weighted imaging sequence, contrast-enhanced T1-weighted and diffusion-weighted imaging (b=0, 1000 s/mm²)] sequence. Two associate chief radiologists performed independent reading without knowing the pathology of the operation.Results The study found that the results of the readers were consistent with the intraoperative peritoneal cancer index, and the intra-group correlation coefficient reached 0.90 (95% confidence interval: 0.64—0.96). Reader 1 (area under the curve=0.96) and reader 2 (area under the curve=0.98) magnetic resonance imaging peritoneal cancer index and intraoperative peritoneal cancer index (area under the curve=0.92) display and complete cytoreductive surgery similar predictions.Conclusions In patients with advanced ovarian cancer, DW-MRI can be regarded as a powerful non-invasive selection tool in the PCI score, which is of great significance for determining whether to perform complete cytoreductive surgery.

[Keywords] cytoreductive surgery；diffusion weighted imaging；magnetic resonance imaging；ovarian cancer；peritoneal cancer

Contributor Information

WAN Zaixin^1* LU Yubo¹ LI Dan²

¹ Department of Radiology, Dandong Hospital of Traditional Chinese Medicine, Dandong 118000, China

² Department of Radiology, Panjin Central Hospital, Panjin 124000, China

Wan ZX, E-mail: wanwanzai@126.com

Conflicts of interest None.

Publication Information

Received 2020-03-27

Accepted 2020-11-25

DOI: 10.12015/issn.1674-8034.2021.02.019

Text

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