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Voxel-based gray matter volume study in patients with vestibular migraine
WANG Jinhui  LIU Bo  YU Dahua  YUAN Kai 

Cite this article as: Wang JH, Liu B, Yu DH, et al. Voxel-based gray matter volume study in patients with vestibular migraine[J]. Chin J Magnc Reson Imaging, 2021, 12(3): 67-70, 88. DOI:10.12015/issn.1674-8034.2021.03.015.


[Abstract] Objective Voxel-based morphological analysis (VBM) was used to analyze the areas of gray matter changes in patients with vestibular migraine (VM), in order to provide new ideas in clinical pathophysiology. Materials andMethods In strict accordance with the inclusion and exclusion criteria, 17 VM patients and 20 healthy controls were recruited. All subjects underwent three-dimensional T1-weighted image magnetic resonance (MRI) scans of the head. VBM was used to compare the brain gray matter volume of the two groups to explore local gray matter changes related to the pathophysiology of the disease.Results Compared with the healthy control group, the gray matter volume of cerebellum, cerebellar vermis, anterior cingulate gyrus, middle orbital frontal gyrus, right temporal transverse gyrus, fusiform gyrus, right angular gyrus of VM patients decreased in VM group (P＜0.001, FEW correction).Conclusion VM patients have multiple pain nociceptive and multisensory integrated brain regions with GM abnormalities. The central brain regions with volume changes may be involved in the pathophysiological mechanism of the disease.
[Keywords] vestibular migraine；gray matter volume；magnetic resonance imaging；voxel based morphometry

WANG Jinhui1   LIU Bo1*   YU Dahua2   YUAN Kai3  

1 Department of Neurology, the First Affiliated Hospital of Baotou Medical College, Baotou 014010, China

2 Inner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, Inner Mongolia University of Science and Technology, Baotou 014010, China

3 School of Life Science and Technology, Xidian University, Xi'an 710071, China

Liu B, E-mail: Liu_Bo2006@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation No. 81871430 Science and Technology Program of Baotou Science and Technology Bureau No. 2018C2007-1-12
Received  2020-11-23
Accepted  2021-01-21
DOI: 10.12015/issn.1674-8034.2021.03.015
Cite this article as: Wang JH, Liu B, Yu DH, et al. Voxel-based gray matter volume study in patients with vestibular migraine[J]. Chin J Magnc Reson Imaging, 2021, 12(3): 67-70, 88. DOI:10.12015/issn.1674-8034.2021.03.015.

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