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• Clinical Article •
Characteristics of endometrial fibrosis on MRI
FENG Yongjing  JIANG Peipei  ZHOU Nan  HU Qing  SUN Shuangshuang  HU Yali  ZHOU Zhengyang 

Cite this article as: Feng YJ, Jiang PP, Zhou N, et al. Characteristics of endometrial fibrosis on MRI[J]. Chin J Magn Reson Imaging, 2021, 12(4): 35-38, 44. DOI:10.12015/issn.1674-8034.2021.04.007.


[Abstract] Objective To explore the structural changes of uterus caused by endometrial fibrosis on magnetic resonance imaging (MRI). Materials andMethods This study prospectively enrolled fifty-three infertility patients with endometrial fibrosis confirmed by hysteroscopic and thirty-four healthy women with childbearing age. All participants received conventional MRI during periovulation phase. Uterine anatomical parameters including endometrial thickness (EMT), length of uterine cavity (LUC) and junctional zone thickness (JZT) were measured and statistically analyzed. A multivariable model using the binary logistic regression analysis was built to predict endometrial fibrosis with indicators that were statistically significant for univariate analysis. AUCs of parameters were compared using Z‐test.Results EMT of patients (7.46±1.14 mm) was significantly thinner than that of healthy women (11.09±2.26 mm) (P＜0.01). LUC of patients (30.79±4.15 mm) was significantly shorter than that of healthy women (36.50±3.25 mm) (P＜0.01). JZT of patients (6.39±1.80 mm) was significantly thicker than that of healthy women (3.98±1.16 mm) (P＜0.01). EMT, LUC, JZT and the multivariable model revealed good performance in diagnosing endometrial fibrosis with AUCs of 0.917, 0.853, 0.883 and 0.974. The AUC of the multivariate model was significantly higher than that of EMT, LUC and JZT, respectively (all P＜0.05).Conclusions MRI can show the structural changes of uterus for patients with endometrial fibrosis visually and dynamically, which makes it a suitable method for clinical follow-up and helping clinicians to grasp the changes of endometrial fibrosis.
[Keywords] fibrosis；endometrium；junctional zone；uterine cavity；infertility；magnetic resonance imaging

FENG Yongjing1   JIANG Peipei2   ZHOU Nan1   HU Qing1   SUN Shuangshuang1   HU Yali2   ZHOU Zhengyang1*  

1 Department of Radiology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China

2 Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China

Zhou ZY, E-mail: zyzhou@nju.edu.cn

Conflicts of interest   None.

This work was part of National Natural Science Foundation of China (No. 81871410); Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDA16040302).
Received  2020-12-16
Accepted  2021-01-29
DOI: 10.12015/issn.1674-8034.2021.04.007
Cite this article as: Feng YJ, Jiang PP, Zhou N, et al. Characteristics of endometrial fibrosis on MRI[J]. Chin J Magn Reson Imaging, 2021, 12(4): 35-38, 44. DOI:10.12015/issn.1674-8034.2021.04.007.

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