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Research progress on the specificity and brain network of acupuncture at Zhigou acupoint based on brain fMRI technology
LI Xiaoling  LIU Shiping  CAO Danna  LIU Xiaohui  CAI Lina  JIANG Xiaoxu  CUI Xuan  LIU Xiao  WANG Feng 

Cite this article as: Li XL, Liu SP, Cao DN, et al. Research progress on the specificity and brain network of acupuncture at Zhigou acupoint based on brain fMRI technology[J]. Chin J Magn Reson Imaging, 2021, 12(5): 110-113. DOI:10.12015/issn.1674-8034.2021.05.027.


[Abstract] The clinical effect of Zhigou point is remarkable and widely used, but the mechanism of acupuncture action is not completely clear, and functional magnetic resonance imaging (fMRI) technology has become an important means to study the mechanism of acupuncture action of brain nerve. After searching and sorting out the literatures related to acupuncture at Zhigou point by using brain fMRI technology, it is known that the specific activation of the brain area by acupuncture at Zhigou point is highly consistent with the structural changes of the brain area related to the diseases of the gastrointestinal tract, and its function is closely related to the regulation of the brain and intestine axis. There was no significant difference between acupuncture point and sham point in the brain activation area, but there was also a relative tendency to some dominant brain areas. Compared with the pure resting state before acupuncture, multiple brain regions have time-varying effects after acupuncture at Zhigou. After acupuncture, the temporary dynamic equilibrium network in the brain of the subjects was broken, and a functional connection network changing with time series was formed between the inferior frontal gyrus and part of the gyri. The purpose of this paper is to provide better guidance and service for clinical treatment by elaborating the changes of specific brain activation areas and brain network connections of acupuncture at Zhigou points.
[Keywords] acupuncture；Zhigou point；functional magnetic resonance imaging；specificity；brain network

LI Xiaoling1   LIU Shiping2   CAO Danna1   LIU Xiaohui2   CAI Lina2   JIANG Xiaoxu2   CUI Xuan2   LIU Xiao3*   WANG Feng1*  

1 Department of CT and MRI, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China

2 Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China

3 Department of Pediatrics, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China

Co corresponding author: Liu X, E-mail: liu_xiao@126.com Wang F, E-mail: wfzmy123@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS General Program of National Natural Science Foundation of China (No. 82074537, 81973930). General Program of Heilongjiang Natural Science Foundation (No. LH2020H103, H2016081). Harbin Science and Technology Innovation Talents Excellent Discipline Leader Fund (No. 2016RAXYJ096). Chunhui Plan of Ministry of Education (No. Z2009-1-15030). Harbin Science and Technology Innovation Talents Special Fund Project (No. 2017RAQXJ180).
Received  2021-01-26
Accepted  2021-03-25
DOI: 10.12015/issn.1674-8034.2021.05.027
Cite this article as: Li XL, Liu SP, Cao DN, et al. Research progress on the specificity and brain network of acupuncture at Zhigou acupoint based on brain fMRI technology[J]. Chin J Magn Reson Imaging, 2021, 12(5): 110-113. DOI:10.12015/issn.1674-8034.2021.05.027.

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