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The quantification methods of the confounding effects in chemical exchange saturation transfer
DOU Han  ZHENG Yang  WANG Xiaoming 

Cite this article as: Dou H, Zheng Y, Wang XM. The quantification methods of the confounding effects in chemical exchange saturation transfer[J]. Chin J Magn Reson Imaging, 2021, 12(5): 118-120, 124. DOI:10.12015/issn.1674-8034.2021.05.029.


[Abstract] Chemical exchange saturation transfer (CEST) is a new molecular imaging technique, which can be used to obtain metabolite concentration information indirectly for clinical diagnosis and prognosis evaluation. However, the CEST signal obtained is not simply from chemical exchange, but contains mixed effects such as direct water saturation (DS), traditional magnetization transfer (MT), nuclear overhauser enhancement (NOE) and so on. How to remove or utilize these effects to improve the quantization accuracy and imaging quality is crucial to clinical transformation.
[Keywords] chemical exchange saturation transfer；magnetic resonance imaging；magnetization transfer；nuclear overhauser enhancement；direct water saturation

DOU Han   ZHENG Yang   WANG Xiaoming*  

Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110000, China

Wang XM, E-mail: wangxm024@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS This article is supported by the National Natural Science Foundation of China (No. 81871408, 81271631). National Science Foundation for Young Scientists of China (No. 81801658). Outstanding Scientific Fund of Shengjing Hospital (No. 201402).
Received  2021-01-26
Accepted  2021-03-22
DOI: 10.12015/issn.1674-8034.2021.05.029
Cite this article as: Dou H, Zheng Y, Wang XM. The quantification methods of the confounding effects in chemical exchange saturation transfer[J]. Chin J Magn Reson Imaging, 2021, 12(5): 118-120, 124. DOI:10.12015/issn.1674-8034.2021.05.029.

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