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• Technical Article •
Resting state functional magnetic resonance imaging of somatic symptom disorder based on fALFF and DC
CUI Yangyang  LIANG Huaibin  ZHU Qian  TANG Wei  GAO Tingting  LIU Jianren  DU Xiaoxia 

Cite this article as: Cui YY, Liang HB, Zhu Q, et al. Resting state functional magnetic resonance imaging of somatic symptom disorder based on fALFF and DC[J]. Chin J Magn Reson Imaging, 2021, 12(7): 51-54. DOI:10.12015/issn.1674-8034.2021.07.010.


[Abstract] Objective Using resting-state functional magnetic resonance image (rs-fMRI) combined with fractional amplitude of low-frequency fluctation (fALFF) and degree centrality (DC) to explore the change of brain function in patients with somatic symptom disorder (SSD), so that it will provide reference information for clinical treatment. Materials andMethods Forty five right-handed patients with somatic symptoms disorder and 43 right-handed healthy controls participated in rs-fMRI scanning. ALFF and DC analysis were used to detect the characteristics of spontaneous brain activity in SSD patients at resting-state. SPM 12 software was used to analyze fMRI data. The statistical threshold of fALFF and DC was voxel level (P＜0.001) by two sample t-test. The cluster level was corrected by family wise error (FWE), P＜0.05. When the cluster more than 10 voxels was reported.Results Patients with SSD showed increased fALFF values in limbic lobe, and thalamus compared with HCs. Besides, atients wit SSD showed decreased DC values in frontal lobe, cingulate gyrus.Conclusions These dysfunction areas seem to have a particular importance for the occurrence of SSD, which may result in dysfunction in emotional processing, interoception, and body perception.
[Keywords] somatic symptom disorder；fractional amplitude of low-frequency fluctation；degree centrality；functional magnetic resonance image

CUI Yangyang1   LIANG Huaibin2   ZHU Qian1   TANG Wei1   GAO Tingting1   LIU Jianren2*   DU Xiaoxia1*  

1 Shanghai Key Laboratory of Magnetic Resonance & Department of Physics,, School of physics and electronics, East China Normal University, Shanghai 200062, China

2 Department of Neurology, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China

Du XX, E-mail: xxdu@phy.ecnu.edu.cn Liu JR E-mail: liujr021@sjtu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS This article research work obtained the National Natural Science Foundation of China (No. 81571658).
Received  2021-01-06
Accepted  2021-03-18
DOI: 10.12015/issn.1674-8034.2021.07.010
Cite this article as: Cui YY, Liang HB, Zhu Q, et al. Resting state functional magnetic resonance imaging of somatic symptom disorder based on fALFF and DC[J]. Chin J Magn Reson Imaging, 2021, 12(7): 51-54. DOI:10.12015/issn.1674-8034.2021.07.010.

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