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Multiparameters of DWI and DCE-MRI in differentiation between parotid Warthin tumor and pleomorphic adenoma
HU Tao  FANG Xuewen  LIU Qiong  ZOU Yujian  YAO Zhaoyou  GAO Yun  ZHANG Kunlin 

Cite this article as: Hu T, Fang XW, Liu Q, et al. Multiparameters of DWI and DCE-MRI in differentiation between parotid Warthin tumor and pleomorphic adenoma[J]. Chin J Magn Reson Imaging, 2021, 12(7): 55-59. DOI:10.12015/issn.1674-8034.2021.07.011.


[Abstract] Objective To investigate the value of multiparametric features including diffusion weighted imaging and dynamic contrast-enhanced MRI in differentiation between parotid Warthin tumor and pleomorphic adenoma (PA). Materials andMethods Forty-eight patients were included in this study including 32 parotid Warthin tumors and 24 pleomorphic adenomas. Conventional and multiparametric MRI features were analyzed. Differences in conventional MRI features, ADCs, previous signal intensity (SIpre)、maximum signal intensity of enhancement (SImax) and signal intensity of the end of enhancement (SIend), wash-out ratio (WR), time to peak (TTP), and time-intensity curves (TICs) types between the two entities were determined by χ2 test and independent samples t-test. Receiver operating characteristic (ROC) curves of parameters being statistically different between groups were drawn for differential diagnosis of Warthin tumor and PA of parotid gland, and the corresponding diagnostic efficacy were analyzed.Results The ages of Warthin tumors were significantly older than those of pleomorphic adenomas (t=9.33, P＜0.05). The male to female ratios were significantly different between the two entities (P＜0.05). The ADCs of Warthin tumors [(0.634±0.201)×10-3 mm2/s] were significantly lower than those of pleomorphic adenomas [(1.084±0.453)×10-3 mm2/s](t=-5.00, P＜0.05). There were significant differences in SIpre (t=4.01, P=0.0002)、WR (t=15.10, P＜0.0001)、TTP (P＜0.05) and TIC types (P＜0.05) between the two entities. Taking ADC=0.811×10-3 mm2/s as threshold drawing ROC for differential diagnosis of Warthin tumor and PA of parotid gland, the area under the curve (AUC), sensitivity, specificity, were 0.845 (P＜0.05), 83.3%, 90.63%. Taking TIC types drawing ROC, the AUC, sensitivity, specificity, were 0.961 (P＜0.05), 95.45%, 100%. Taking ADCs combined with TIC types drawing ROC, the AUC, sensitivity, specificity, were 0.984 (P＜0.05), 100%, 96.88%.Conclusions Multiparameters and combined parameters of DWI and DCE-MRI were helpful to differential diagnosis of Warthin tumor and pleomorphic adenoma of parotid.
[Keywords] parotid gland；adenolymphoma；adenoma, pleomorphic；diagnosis, differential；magnetic resonance imaging

HU Tao1   FANG Xuewen1*   LIU Qiong2   ZOU Yujian1   YAO Zhaoyou3   GAO Yun1   ZHANG Kunlin1  

1 Department of Radiology, Dongguan People's Hospital of Guangdong Province, Dongguan 523000, China

2 Department of Sub-health, Dongguan People's Hospital of Guangdong Province, Dongguan 523000, China

3 Department of Oral and Maxillofacial Surgery, Dongguan People's Hospital of Guangdong Province, Dongguan 523000, China

Fang XW, E-mail: 1264968430@qq.com

Conflicts of interest   None.

Received  2021-01-29
Accepted  2021-03-25
DOI: 10.12015/issn.1674-8034.2021.07.011
Cite this article as: Hu T, Fang XW, Liu Q, et al. Multiparameters of DWI and DCE-MRI in differentiation between parotid Warthin tumor and pleomorphic adenoma[J]. Chin J Magn Reson Imaging, 2021, 12(7): 55-59. DOI:10.12015/issn.1674-8034.2021.07.011.

1
Comoglu S, Ozturk E, Celik M, et al. Comprehensive analysis of parotid mass: a retrospectective study of 369 cases[J]. Auris Nasus arynx, 2018, 45(2): 320-327. DOI: 10.1016/j.anl.2017.04.003.
2
Hellquist H, Paiva-Correia A, Vander PV, et al. Analysis of the clinical relevance of histological classification of benign epithelial salivary gland tumours[J]. Adv Ther, 2019, 36(8): 1950-1974. DOI: 10.1007/s12325-019-01007-3.
3
Coudert H, Mirafzal S, Dissard A, et al. Multiparametric magnetic resonance imaging of parotid tumors: a systematic review[J]. Diagn Interv Imaging, 2020, 102(3): 121-130. DOI: 10.1016/j.diii.2020.08.002.
4
Elmokadem AH, Abdel Khalek AM, Abdel Wahab RM, et al. Diagnostic accuracy of multiparametric magnetic resonance imaging for differentiation between parotid neoplasms[J]. Can Assoc Radiol J, 2019, 70(3): 264-272. DOI: 10.1016/j.carj.2018.10.010.
5
Pietragalla M, Nardi C, Bonasera L, et al. The role of diffusion-weighted and dynamic contrast enhancement perfusion-weighted imaging in the evaluation of salivary glands neoplasms[J]. Radiol Med, 2020, 125(9): 851-863. DOI: 10.1007/s11547-020-01182-2.
6
Wang CW, Chu YH, Chiu DY, et al. Journal Club: The warthin tumor score: a simple and reliable method to distinguish warthin tumors from pleomorphic adenomas and carcinomas[J]. AJR Am J Roentgenol, 2018, 210(6): 1330-1337. DOI: 10.2214/AJR.17.18492.
7
Jiang H, Chen QH, Wang YZ, et al. Value of muItiparametric MRI in differentiation between solitary parotid Warthin tumor and pIeomorphic adenoma[J]. Chin J Arch Otolaryngol Head Neck Surg, 2020, 27(3): 115-118.
8
Chu XL, Wang Y, Wang ZF, et al. Enhanced CT combined with histogram analysis for differential diagnosis of Warthin tumor and polymorphic adenoma of parotid gland[J]. Chin J Med Imaging Technol, 2020, 36(8): 1177-1182.
9
Zeng XT, Zheng SY, Shen JH, et al. Differential diagnosis of parotid masses by dynamic contrast-enhanced MR[J]. Diagn Imaging Interv Radiol, 2015, 24(4): 277-282.
10
Lee DH, Yoon TM, Lee JK, et al. Surgical treatment strategy in Warthin tumor of the parotid gland[J]. Braz J Otorhinolaryngol, 2019, 85(5): 546-550. DOI: 10.1016/j.bjorl.2018.04.004.
11
Tong J, Hu CH, Wang XL, et al. Diffusion-weighted imaging combined with dynamic contrast-enhanced MRI in parotid gland tumors[J]. Chin J Med Imaging Technol, 2017, 33(8): 1197-1201.
12
Aaka R. Multi-parametric MR imaging using pseudo-continuous arterial-spin labeling and diffusion-weighted MR imaging in differentiating subtypes of parotid tumors[J]. Magn Reson Imaging, 2019, 63: 55-59. DOI: 10.1016/j.mri.2019.08.005.
13
Yamamoto T, Kimura H, Hayashi K, et al. Pseudo-continuous arterial spin labeling MR images in Warthin tumors and pleomorphic adenomas of the parotid gland: qualitative and quantitative analyses and their correlation with histopathologic and DWI and dynamic contrast enhanced MRI findings[J]. Neuroradiology, 2018, 60(8): 803-812. DOI: 10.1007/s00234-018-2046-9.
14
Matsusue E, Fujihara Y, Matsuda E, et al. Differentiating parotid tumors by quantitative signal intensity evaluation on MR imaging[J]. Clin Imaging, 2017, 46: 37-43. DOI: 10.1016/j.clinimag.2017.06.009.
15
Khalifa F,Soliman A,El-Baz A,et a1. Models and methods for analyzing DCE-MRI:a review[J]. Med Phys, 2014, 41(12): 124301. DOI: 10.1118/1.4898202.
16
Kato H, Kanematsu M, Watanabe H, et al. Salivary gland tumors of the parotid gland: CT and MR imaging findings with emphasis on intratumoral cystic components[J]. Neuroradiology, 2014, 56(9): 789-795. DOI: 10.1007/s00234-014-1386-3.
17
Jia CH, Cao R, Kuai XP, et al. Conventional and functional MRI features of parotid Warthin tumor: correlation with clinicopathological findings[J]. Chin J Stomatol, 2019, 54(2): 94-100.
18
Tartaglione T, Botto A, Sciandra M, et al. Differential diagnosis of parotid gland tumours: which magnetic resonance findings should be taken in account[J]. Acta Otorhinolaryngol Ital, 2015, 35(5): 314-20. DOI: 10.14639/0392-100X-693.
19
Ogawa T, Kojima I, Ishii R, et al. Clinical utility of dynamic-enhanced MRI in salivary gland tumors: retrospective study and literature review[J]. Eur Arch Otorhinolaryngol, 2018, 275(6): 1613-1621. DOI: 10.1007/s00405-018-4965-9.
20
Man YP, Ma LB, Lin H, et al. Value of multimodal MRI in diagnosis of parotid pleomorphic adenoma and adenolymphoma[J]. Radiologic Practice, 2018, 33(12): 1241-1245.
21
Zheng N, Li R, Liu W, et al. The diagnostic value of combining conventional, diffusion-weighted imaging and dynamic contrast-enhanced MRI for salivary gland tumors[J]. Br J Radiol, 2018, 91(1089): 20170707. DOI: 10.1259/bjr.20170707.
22
Yabuuchi H, Kamitani T, Sagiyama K, et al. Characterization of parotid gland tumors: added value of permeability MR imaging to DWI and DCE-MRI[J]. Eur Radiol, 2020, 30(12): 6402-6412. DOI: 10.1007/s00330-020-07004-3.
23
Pietragalla M, Nardi C, Bonasera L, et al. The role of diffusion-weighted and dynamic contrast enhancement perfusion-weighted imaging in the evaluation of salivary glands neoplasms[J]. Radiol Med, 2020, 125(9): 851-863. DOI: 10.1007/s11547-020-01182-2.

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