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MRI features and pathological mechanism of solitary plasmacytoma in the spine
SHANG Liutong  YANG Shuhui  HU Mingyan  WANG Hongwei  LI Tianran 

Cite this article as: Shang LT, Yang SH, Hu MY, et al. MRI features and pathological mechanism of solitary plasmacytoma in the spine[J]. Chin J Magn Reson Imaging, 2021, 12(7): 77-79, 101. DOI:10.12015/issn.1674-8034.2021.07.016.


[Abstract] Objective To explore the MRI features and pathological mechanism of solitary plasmacytoma of the spine (SPS), so as to improve the understanding and diagnosis of SPS and provide the basis for treatment. Materials andMethods MRI data of 17 patients with SPS confirmed by surgery and pathology were retrospectively analyzed. The MRI features and pathological mechanism were analyzed.Results The tumors were located in cervical vertebrae in 1 case, thoracic vertebrae in 8 cases and lumbar vertebrae in 8 cases. Seventeen cases of SPS showed varying degrees of osteolytic bone destruction, mild swelling changes. Fourteen cases involving accessories, 13 cases of vertebral compression wedge. Thirteen cases of vertebral edge formation of asymmetric soft tissue masses, 12 cases of soft tissue masses protruding into the spinal canal, 7 cases surrounding the spinal canal to form a "encircling sign". Tumor mostly showed isointensity or slightly hypointensity on T1WI, and isointensity or slightly hyperintensity on T2WI. Enhanced scans were clearly and uniformly enhanced, 14 cases showed "mini brain like" sign. Histopathological features: the tumor cells are composed of small round cells with diffuse and dense arrangement, almost no intercellular matrix. Immunophenotype: 17 cases expressed CD138 and CD38, 12 cases expressed KAP, 7 cases expressed Lambda, 11 cases expressed CD79a, only 2 cases expressed CD20.Conclusions The MRI features of SPS have certain characteristics. Understanding its MRI features and related pathological mechanism can be helpful to differentiate SPS from other single spinal tumors and improve the accuracy of preoperative diagnosis.
[Keywords] spine；solitary plasmacytoma；magnetic resonance imaging；imaging features；pathology

SHANG Liutong1   YANG Shuhui1   HU Mingyan1   WANG Hongwei2   LI Tianran1*  

1 Diagnostic Radiology Departmen of the Fourth Medical Center of Chinese PLA General Hospital, Beijing 100048, China

2 Pathology Department of the Fourth Medical Center of Chinese PLA General Hospital, Beijing 100048, China

Li TR, E-mail: ltranmd@yeah.net

Conflicts of interest   None.

Received  2021-01-29
Accepted  2021-05-18
DOI: 10.12015/issn.1674-8034.2021.07.016
Cite this article as: Shang LT, Yang SH, Hu MY, et al. MRI features and pathological mechanism of solitary plasmacytoma in the spine[J]. Chin J Magn Reson Imaging, 2021, 12(7): 77-79, 101. DOI:10.12015/issn.1674-8034.2021.07.016.

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