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Value of MRI and cerebrospinal fluid examination in evaluating the curative effect of intracranial tuberculosis
JI Junyu  SHEN Jing  GENG Guang  HAO Meng  HUANG Na 

Cite this article as: Ji JY, Shen J, Geng G, et al. Value of MRI and cerebrospinal fluid examination in evaluating the curative effect of intracranial tuberculosis[J]. Chin J Magn Reson Imaging, 2021, 12(8): 71-74. DOI:10.12015/issn.1674-8034.2021.08.014.


[Abstract] Objective To analyze the value of magnetic resonance imaging (MRI) and cerebrospinal fluid examination in evaluating the curative effect of intracranial tuberculosis. Materials andMethods The study retrospectively reviewed 400 patients with intracranial tuberculosis who received MRI examination in the hospital between January 2012 and December 2017, who were treated with antituberculous therapy. The size and number of lesions, CSF biochemical indicators (CSF protein, glucose, CSF adenosine deaminase) and CSF cytological indicators (WBC count, monocyte count, granulocyte count, intracranial pressure, lymphocyte count) were compared before treatment and 6 months after treatment.Results MRI images showed that after 6 months of treatment, the number and size of the lesions were reduced (P＜0.05), and the disappearance rate of lesions was 71.59% (5767/8056). Cerebrospinal fluid protein, glucose, and adenosine deaminase levels were lower than those before treatment, while chloride levels were higher than those before treatment (P＜0.05). The white blood cell count, monocytes, neutrophil count, intracranial pressure and lymphocyte count were significantly lower than those before treatment (P＜0.05). Meanwhile, MRI examination showed that 316 cases were cured, accounting for 79.00%, while cerebrospinal fluid examination showed that 298 cases were cured, accounting for 74.50%, without statistically significant difference (P＞0.05), Kappa value=0.595.Conclusions After anti-tuberculosis treatment, the number and size of the lesions are reduced, and the cerebrospinal fluid examination indicators are improved. MRI examination and cerebrospinal fluid examination of intracranial tuberculosis have a higher consistency in evaluating the prognosis of patients. The combined use of the two can help doctors evaluate treatment effects and prognosis.
[Keywords] intracranial tuberculosis；magnetic resonance imaging；cerebrospinal fluid examination；diagnosis；clinical outcome

JI Junyu*   SHEN Jing   GENG Guang   HAO Meng   HUANG Na  

Department of Radiology, Chest Hospital of Hebei Province, Shijiazhuang 050041, China

Ji JY, E-mail: jijunyu2008@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS This work was part of Hebei Province Medical Science Research Key Project Plan (No. 20170430).
Received  2021-03-11
Accepted  2021-05-13
DOI: 10.12015/issn.1674-8034.2021.08.014
Cite this article as: Ji JY, Shen J, Geng G, et al. Value of MRI and cerebrospinal fluid examination in evaluating the curative effect of intracranial tuberculosis[J]. Chin J Magn Reson Imaging, 2021, 12(8): 71-74. DOI:10.12015/issn.1674-8034.2021.08.014.

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