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Research progress of multi-modal imaging techniques in Parkinson's disease with freezing of gait
WANG Xinhui  BAI Yan  WEI Wei  SHEN Yu  WANG Meiyun 

Cite this article as: Wang XH, Bai Y, Wei W, et al. Research progress of multi-modal imaging techniques in Parkinson's disease with freezing of gait[J]. Chin J Magn Reson Imaging, 2021, 12(8): 81-84. DOI:10.12015/issn.1674-8034.2021.08.017.


[Abstract] Freezing of gait (FOG) is a common paroxysmal gait disorder in Parkinson's disease (PD). FOG manifests as sudden interruption in walking and severe movement difficulties, which increases the risk of falling and declines the quality of life. However, the neuropathophysiological mechanism of PD-FOG is still unclear. The previous study uses multi-modal imaging techniques to the changes in the brain function and structure of PD patients with or without FOG, and links these findings with the severity of FOG. This article reviews the research progress of multimodal imaging technology in the diagnosis and treatment of PD patients with FOG.
[Keywords] Parkinson's disease；freezing gait；medical imaging；magnetic resonance imaging；nuclear medicine

WANG Xinhui1, 2   BAI Yan1, 2   WEI Wei1, 2   SHEN Yu1, 2   WANG Meiyun1, 2*  

1 Department of Medical Imaging, the People's Hospital of Zhengzhou University, Zhengzhou 450003

2 Department of Medical Imaging, Henan Provincial People's Hospital, Zhengzhou;450003, China

Wang MY, E-mail: mywang@ha.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS This work was part of National Key R&D Program Project (No. 2017YFE0103600); National Natural Science Foundation of China (No. 81720108021); Henan Province Medical Science and Technology Research Project (No. SBGJ202003002).
Received  2021-04-19
Accepted  2021-05-24
DOI: 10.12015/issn.1674-8034.2021.08.017
Cite this article as: Wang XH, Bai Y, Wei W, et al. Research progress of multi-modal imaging techniques in Parkinson's disease with freezing of gait[J]. Chin J Magn Reson Imaging, 2021, 12(8): 81-84. DOI:10.12015/issn.1674-8034.2021.08.017.

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