Share:
Share this content in WeChat
X
Experience Exchanges
Application value of conventional MRI examination and diffusion weighted imaging in preoperative evaluation of rectal cancer
YANG Hongyu  GAO Xu  SHEN Xiuzhi  ZHONG Jiali  PENG Ruchen 

Cite this article as: Citation:Yang HY, Gao X, Shen XZ, et al. Application value of conventional MRI examination and diffusion weighted imaging in preoperative evaluation of rectal cancer[J]. Chin J Magn Reson Imaging, 2021, 12(9): 65-68, 87. DOI:10.12015/issn.1674-8034.2021.09.015.


[Abstract] Objective To analyze the value of conventional MRI and diffusion weighted imaging (DWI) in preoperative evaluation of rectal cancer. Materials andMethods The data of 42 rectal cancer patients in our hospital were collected retrospectively,all patients underwent pelvic MRI+DWI+enhancement scan before surgery,the T, N stages and circumferential resection margin (CRM) of rectal cancer were evaluated by MRI imaging performance, and the results were compared with the postoperative pathology to evaluate the accuracy of conventional MRI+DWI in the diagnosis of rectal cancer. The application value of DWI in the diagnosis and preoperative evaluation of rectal cancer was explored by measuring the ADC value of the tumor.Results The results showed good agreement between the preoperative T ,N stages and CRM assessed by conventional MRI+DWI and the postoperative pathological results (Kappa values of 0.745, 0.691 and 0.642, respectively). Comparison of ADC value of rectal cancer with different T stages showed that the higher the T stage with the lower the ADC value, and the difference of ADC value between groups was statistically significant (T1—2 group compared with T3 group: P=0.015;T3 group compared with T4 group: P=0.01). The ADC value of CRM-positive was lower than that of CRM-negative, and the difference was statistically significant (P=0.015).Conclusions Conventional MRI and DWI imaging have high application value in preoperative staging and CRM evaluation of rectal cancer. The value of ADC has a certain reference value for the diagnosis and preoperative evaluation of rectal cancer.
[Keywords] rectal cancer;magnetic resonance imaging;apparent diffusion coefficient value;tumor stage;pathology

YANG Hongyu1   GAO Xu2   SHEN Xiuzhi1   ZHONG Jiali1   PENG Ruchen1*  

1 Department of Medical Imaging, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

2 Department of General Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

Peng RC, E-mail: pengruchen@ccmu.edu.cn

Conflicts of interest   None.

Received  2021-03-03
Accepted  2021-04-01
DOI: 10.12015/issn.1674-8034.2021.09.015
Cite this article as: Citation:Yang HY, Gao X, Shen XZ, et al. Application value of conventional MRI examination and diffusion weighted imaging in preoperative evaluation of rectal cancer[J]. Chin J Magn Reson Imaging, 2021, 12(9): 65-68, 87. DOI:10.12015/issn.1674-8034.2021.09.015.

[1]
Barreto SG. Young-onset rectal cancer patients: in need of answers[J]. Future Oncol, 2019, 15(10): 1053-1055. DOI: 10.2217/fon-2019-0002.
[2]
Sun W, Al-Rajabi R, Perez RO, et al. Controversies in rectal cancer treatment and management[J]. Am Soc Clin Oncol Educ Book, 2020, 40: 1-11. DOI: 10.1200/EDBK_279871.
[3]
Gurses B, Boge M, Altinmakas E, et al. Multiparametric MRI in rectal cancer[J]. Diagn Interv Radiol, 2019, 25(3): 175-182. DOI: 10.5152/dir.2019.18189.
[4]
Amin MB. AJCC cancer staging manual[M]. 8th ed, Berlin: Springer, 2017.
[5]
Lu CW, Zhang B. Application value of CT and MR in preoperative TN staging of pelvic colorectal cancer[J]. J Med Imaging, 2015, 25(7): 1204-1208, 1220.
[6]
Liu DD, Hou WH, Qi S, et al. Application of 3.0 T MRI in preoperative evaluation of rectal cancer[J]. J Pract Radiol, 2017, 33(4): 537-541. DOI: 10.3969/ji.ssn.1002-1671.2017.04.013.
[7]
Liu Q, Luo D, Cai S, et al. Circumferential resection margin as a prognostic factor after rectal cancer surgery: a large population-based retrospective study[J]. Cancer Med, 2018, 7(8): 3673-3681. DOI: 10.1002/cam4.1662.
[8]
Zhang G, Cai YZ, Xu GH. Diagnostic accuracy of MRI for assessment of T category and circumferential resection margin involvement in patients with rectal cancer: a Meta-analysis[J]. Dis Colon Rectum, 2016, 59(8): 789-799. DOI: 10.1097/DCR.0000000000000611.
[9]
Horvat N, Carlos TRC, Clemente OB, et al. MRI of rectal cancer: tumor staging, imaging techniques, and management[J]. Radiographics, 2019, 39(2): 367-387. DOI: 10.1148/rg.2019180114.
[10]
Cai Z, Xie X, Chen Y, et al. Risk factor analysis for inaccurate pre-operative MRI staging in rectal cancer[J]. BMC Cancer, 2020, 20(1): 253. DOI: 10.1186/s12885-020-06761-0.
[11]
Danihel LJ, Danihel LS, Rajcok M, et al. Significance of MRI in rectal carcinoma therapy optimization: correlation of preoperative T-and N-staging with definitive histopathological findings[J]. Neoplasma, 2019, 66(3): 494-498. DOI: 10.4149/neo_2018_180522N334.
[12]
Liu Y, Wen Z, Yang X, et al. Lymph node metastasis in rectal cancer: comparison of MDCT and MR imaging for diagnostic accuracy[J]. Abdom Radiol (NY), 2019, 44(11): 3625-3631. DOI: 10.1007/s00261-019-02240-8.
[13]
Stijns RC, Scheenen TW, de Wilt JH, et al. The influence of endorectal filling on rectal cancer staging with MRI[J]. Br J Radiol, 2018, 91(1089): 20180205. DOI: 10.1259/bjr.20180205.
[14]
Glynne-Jones R, Wyrwicz L, Tiret E, et al. Rectal cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up[J]. Ann Oncol, 2017, 28(suppl 4): v22-v40. DOI: 10.1093/annonc/mdx224.
[15]
Beets-Tan R, Lambregts D, Maas M, et al. Magnetic resonance imaging for clinical management of rectal cancer: updated recommendations from the 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting[J]. Eur Radiol, 2018, 28(4): 1465-1475. DOI: 10.1007/s00330-017-5026-2.
[16]
Zheng N, Li YY, Cao YC, et al. Evaluation of magnetic resonance imaging in staging of rectal cancer and its relationship with P16 expression[J]. Eur Rev Med Pharmacol Sci, 2018, 22(12): 3755-3762. DOI: 10.26355/eurrev_201806_15257.
[17]
Otero DPJ, Mayol J. Controversies in the management of lateral pelvic lymph nodes in patients with advanced rectal cancer: east or west?[J]. Front Surg, 2019, 6: 79. DOI: 10.3389/fsurg.2019.00079.
[18]
Steup WH, Moriya Y, van de Velde CJ. Patterns of lymphatic spread in rectal cancer. A topographical analysis on lymph node metastases[J]. Eur J Cancer, 2002, 38(7): 911-918. DOI: 10.1016/s0959-8049(02)00046-1.
[19]
Faletti R, Gatti M, Arezzo A, et al. Preoperative staging of rectal cancer using magnetic resonance imaging: comparison with pathological staging[J]. Minerva Chir, 2018, 73(1): 13-19. DOI: 10.23736/S0026-4733.17.07392-8.
[20]
Van Cutsem E, Cervantes A, Adam R, et al. ESMO consensus guidelines for the management of patients with metastatic colorectal cancer[J]. Ann Oncol, 2016, 27(8): 1386-1422. DOI: 10.1093/annonc/mdw235.
[21]
Taylor FG, Quirke P, Heald RJ, et al. Preoperative high-resolution magnetic resonance imaging can identify good prognosis stage I, II, and III rectal cancer best managed by surgery alone: a prospective, multicenter, European study[J]. Ann Surg, 2011, 253(4): 711-719. DOI: 10.1097/SLA.0b013e31820b8d52.
[22]
Hoeffel C, Mule S, Laurent V, et al. Current imaging of rectal cancer[J]. Clin Res Hepatol Gastroenterol, 2015, 39(2): 168-173. DOI: 10.1016/j.clinre.2014.07.014.
[23]
Gurses B, Altinmakas E, Boge M, et al. Multiparametric MRI of rectal cancer-repeatability of quantitative data: a feasibility study[J]. Diagn Interv Radiol, 2020, 26(2): 87-94. DOI: 10.5152/dir.2019.19127.
[24]
Curvo-Semedo L, Lambregts DM, Maas M, et al. Diffusion-weighted MRI in rectal cancer: apparent diffusion coefficient as a potential noninvasive marker of tumor aggressiveness[J]. J Magn Reson Imaging, 2012, 35(6): 1365-1371. DOI: 10.1002/jmri.23589.
[25]
Lu ZH, Qian WX, Cao WH, et al. Diagnostic value of magnetic resonance diffusion weighted imaging in T staging of rectal cancer[J]. Chin J Gastrointest Surgery, 2015, 18(3): 257-261. DOI: 10.3760/cma.j.issn.1671-0274.2015.03.013.

PREV Diagnostic value of DCE-MRI combined with DWI for central gland prostate cancer
NEXT Preliminary study of APT combined with T2 mapping sequence in preoperative risk assessment of endometrial carcinoma
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn